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    BIOMARKER:

    FOLR1 overexpression

    i
    Other names: FOLR1, Folate Receptor Alpha, Ovarian Tumor-Associated Antigen MOv18, Adult Folate-Binding Protein, Folate Receptor 1 (Adult), Folate Receptor, Adult, Folate Receptor 1, KB Cells FBP, FR-Alpha, FOLR, FBP, Folate Binding Protein, FRalpha
    Entrez ID:
    2348
    Related biomarkers:
    Expression
    over1year
    #ASH22 #leusm Meshinchi: CBF/GLIS2 translation -> high risk AML in infants, FOLR1 overexpressed, FOLR1 ADC (Luveltamab, STRO-002) led to MRD neg CR in 41% wo myelosuppr. Fascinating biol & outcomes, unfortunately only relevant to this infant AML; FOLR1 not overexpr in other leuks (@hemedoc)
    FOLR1 ( Folate receptor alpha ) • GLIS2 (GLIS Family Zinc Finger 2)
    |
    FOLR1 overexpression
    |
    luveltamab tazevibulin (STRO-002)