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BIOMARKER:
FLT3 N676K
i
Other names:
FLT3, Fms Related Tyrosine Kinase 3, Receptor-Type Tyrosine-Protein Kinase FLT3, Stem Cell Tyrosine Kinase 1, Fms-Like Tyrosine Kinase 3, CD135, FLK-2, STK1, Growth Factor Receptor Tyrosine Kinase Type III, Fetal Liver Kinase 2
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Entrez ID:
2322
Related biomarkers:
Expression
Mutation
CNA
Fusion
Others
‹
NUP98-NSD1 fusion + FLT3-ITD mutation (3)
CD123 positive + FLT3-ITD mutation (1)
CSK overexpression + FLT3-ITD mutation (1)
EPHB2 overexpression + FLT3-ITD mutation (1)
FLT3 A848P + MLL-MLLT3 fusion (1)
FLT3 wild-type + TP53 mutation (1)
FLT3-ITD mutation + MLL fusion + TP53 mutation (1)
FLT3-ITD mutation + PML-RARA fusion + WT1 overexpression (1)
FLT3-ITD mutation + RIPK1 expression (1)
FLT3-ITD mutation + SKI overexpression (1)
HCK overexpression + FLT3-ITD mutation (1)
HLF overexpression + FLT3-ITD mutation (1)
KAT6A-CREBBP fusion + FLT3-TKD mutation (1)
LYN overexpression + FLT3-ITD mutation (1)
miR-155 deletion + FLT3-ITD mutation (1)
NUP98-NSD1 fusion + FLT3-ITD mutation (3)
CD123 positive + FLT3-ITD mutation (1)
CSK overexpression + FLT3-ITD mutation (1)
EPHB2 overexpression + FLT3-ITD mutation (1)
FLT3 A848P + MLL-MLLT3 fusion (1)
FLT3 wild-type + TP53 mutation (1)
FLT3-ITD mutation + MLL fusion + TP53 mutation (1)
FLT3-ITD mutation + PML-RARA fusion + WT1 overexpression (1)
FLT3-ITD mutation + RIPK1 expression (1)
FLT3-ITD mutation + SKI overexpression (1)
HCK overexpression + FLT3-ITD mutation (1)
HLF overexpression + FLT3-ITD mutation (1)
KAT6A-CREBBP fusion + FLT3-TKD mutation (1)
LYN overexpression + FLT3-ITD mutation (1)
miR-155 deletion + FLT3-ITD mutation (1)
›
Associations
(4)
News
Trials
Search handles
@RoloffGreg
Search handles
@RoloffGreg
Filter by
Latest
9ms
Check out the final version of the @UChicagoLeuk article on FLT3 inhibitors in pts with FLT3 N676K mutated AML! The effort was led by @RoloffGreg @michaelwd https://t.co/VLDjMBnnfH (@UChicagoLeuk)
9 months ago
Clinical
|
FLT3 (Fms-related tyrosine kinase 3)
|
FLT3 N676K
over1year
We meet the occasional AML pt with a FLT3 mutation outside the classic ITD/TKD sites. A common one is FLT3 N676K. Check out our new @UChicagoLeuk analysis of this atypical variant's responsiveness to FLT3i @michaelwd @UCCancerCenter @UCHemOncFellows https://t.co/1V2zGyqqSd (@RoloffGreg)
over 1 year ago
FLT3 (Fms-related tyrosine kinase 3)
|
FLT3 mutation • FLT3 N676K
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