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BIOMARKER:
ER positive + PGR positive
i
Other names:
PGR, Progesterone receptor, Nuclear receptor subfamily 3 group C member 3, NR3C3, ESR1, Era, ESR, NR3A1, ER, ER beta
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Entrez ID:
2099
;
5241
Related biomarkers:
Expression
Mutation
CNA
Fusion
Others
‹
PIK3CA mutation + HR positive (16)
PIK3CA mutation + ER positive (10)
ESR1 mutation + HR positive (6)
ESR1 wild-type + HR positive (4)
BRCA1 mutation + HR positive (3)
BRCA2 mutation + HR positive (3)
ER positive + PIK3CA H1047R (3)
FGFR1 amplification + HR positive (3)
HR positive + BRCA2 mutation (3)
HR-positive + PIK3CA wild-type (3)
PIK3CA exon 20 mutation + HR positive (3)
AKT1 E17K + HR positive (2)
AKT1 mutation + HR positive (2)
ER Y537S + ER positive (2)
ER positive + TP53 mutation (2)
ER-L (2)
HR negative + BRCA1 mutation (2)
HR negative + BRCA2 mutation (2)
HR positive + BRCA1 mutation (2)
HR positive + MYC amplification (2)
HR positive + TP53 mutation (2)
PIK3CA mutation + ER negative (2)
AKT1 mutation + ER negative (1)
AKT1 mutation + ER positive (1)
BRCA1 mutation + HER-2 negative + ER positive + PGR positive (1)
BRCA2 mutation + ER positive (1)
BRCA2 mutation + ER positive + PGR positive (1)
CCND1 mutation + HR positive (1)
CCND2 mutation + HR positive (1)
CCNE1 overexpression + PIK3CA muattion + ER positive (1)
CCNE2 overexpression + PIK3CA mutation + ER positive (1)
CDK4 mutation + HR positive (1)
CDKN1B mutation + HR positive (1)
EGFR mutation + ER positive (1)
ER D538G + ER positive (1)
ER E380Q + ER positive (1)
ER L536H + ER D538G + CCND1 amplification (1)
ER Y537N + ER positive (1)
ER negative + HER-2 positive + PGR positive + PIK3CA mutation (1)
ER positive + ESR1 mutation + CCND1 amplification (1)
ER positive + ESR1 mutation + FGFR1 amplification (1)
ER positive + ESR1 mutation + PIK3CA mutation (1)
ER positive + ESR1 mutation + TP53 mutation (1)
ER positive + FGFR1 amplification (1)
ER positive + FGFR3 amplification (1)
ER positive + HER-2 D769H + HER-2 V777L (1)
ER positive + MLH1 1835del3 + MSI-H/dMMR + TMB-H (1)
ER positive + ZNF217 overexpression (1)
ER underexpression + ER Y537S (1)
ERBB4 H809G + ER positive (1)
ESR1 mutation + PIK3CA mutation + HR positive (1)
FGF19 amplification + ER positive (1)
FGF3 amplification + ER positive (1)
FGF4 amplification + ER positive (1)
FOXA1 expression + ER positive (1)
HER-2 amplification + ER positive + PGR negative (1)
HR negative + EGFR amplification (1)
HR positive + APOBEC signature (1)
HR positive + AURKA amplification (1)
HR positive + AURKA mutation (1)
HR positive + BRAF V600E (1)
HR positive + BRCA1 mutation + PALB2 mutation (1)
HR positive + BRCA2 mutation + PALB2 mutation (1)
HR positive + BRIP1 amplification (1)
HR positive + CCND1 amplification (1)
HR positive + HER-2 amplification (1)
HR positive + HER-2 mutation (1)
HR positive + MYC mutation (1)
HR positive + PIK3CA exon 10 mutation (1)
HR positive + PTEN deletion (1)
HR positive + RAD51C amplification (1)
HR positive + RB1 mutation (1)
HR positive + TMB-H (1)
HR positive + TMB-L (1)
High HDAC6 score + HR positive (1)
KRAS mutation + CDK9 overexpression + HR positive (1)
KRAS mutation + ER expression (1)
KRAS mutation + HR positive (1)
MTOR mutation + HR positive (1)
MYC mutation + ER positive (1)
PIK3CA E542K + HR positive (1)
PIK3CA amplification + PIK3CA mutation + HR positive (1)
PIK3CA exon 7 mutation + HR positive (1)
PIK3CA exon 9 mutation + HR positive (1)
PIK3CA mutation + ESR1 wild-type (1)
PIK3CA mutation + HR positive + HER-2 negative (1)
PIK3CA wild-type+ ESR1 wild-type (1)
PTEN deletion + ER positive (1)
PTEN mutation + HR positive (1)
TP53 wild-type + ER positive (1)
AKT1 E17K + CTNNB1 G34R + ER Y537S + MSI-H (0)
ER negative + HER-2 positive + PIK3CA H1047R (0)
ER positive + BRCA1 mutation (0)
ER positive + BRCA2 mutation (0)
ER positive + HER-2 negative + ER mutation (0)
HR positive + HER-2 negative + TMB-L (0)
PIK3CA mutation + ER negative + PGR positive (0)
PIK3CA mutation + HR positive (16)
PIK3CA mutation + ER positive (10)
ESR1 mutation + HR positive (6)
ESR1 wild-type + HR positive (4)
BRCA1 mutation + HR positive (3)
BRCA2 mutation + HR positive (3)
ER positive + PIK3CA H1047R (3)
FGFR1 amplification + HR positive (3)
HR positive + BRCA2 mutation (3)
HR-positive + PIK3CA wild-type (3)
PIK3CA exon 20 mutation + HR positive (3)
AKT1 E17K + HR positive (2)
AKT1 mutation + HR positive (2)
ER Y537S + ER positive (2)
ER positive + TP53 mutation (2)
ER-L (2)
HR negative + BRCA1 mutation (2)
HR negative + BRCA2 mutation (2)
HR positive + BRCA1 mutation (2)
HR positive + MYC amplification (2)
HR positive + TP53 mutation (2)
PIK3CA mutation + ER negative (2)
AKT1 mutation + ER negative (1)
AKT1 mutation + ER positive (1)
BRCA1 mutation + HER-2 negative + ER positive + PGR positive (1)
BRCA2 mutation + ER positive (1)
BRCA2 mutation + ER positive + PGR positive (1)
CCND1 mutation + HR positive (1)
CCND2 mutation + HR positive (1)
CCNE1 overexpression + PIK3CA muattion + ER positive (1)
CCNE2 overexpression + PIK3CA mutation + ER positive (1)
CDK4 mutation + HR positive (1)
CDKN1B mutation + HR positive (1)
EGFR mutation + ER positive (1)
ER D538G + ER positive (1)
ER E380Q + ER positive (1)
ER L536H + ER D538G + CCND1 amplification (1)
ER Y537N + ER positive (1)
ER negative + HER-2 positive + PGR positive + PIK3CA mutation (1)
ER positive + ESR1 mutation + CCND1 amplification (1)
ER positive + ESR1 mutation + FGFR1 amplification (1)
ER positive + ESR1 mutation + PIK3CA mutation (1)
ER positive + ESR1 mutation + TP53 mutation (1)
ER positive + FGFR1 amplification (1)
ER positive + FGFR3 amplification (1)
ER positive + HER-2 D769H + HER-2 V777L (1)
ER positive + MLH1 1835del3 + MSI-H/dMMR + TMB-H (1)
ER positive + ZNF217 overexpression (1)
ER underexpression + ER Y537S (1)
ERBB4 H809G + ER positive (1)
ESR1 mutation + PIK3CA mutation + HR positive (1)
FGF19 amplification + ER positive (1)
FGF3 amplification + ER positive (1)
FGF4 amplification + ER positive (1)
FOXA1 expression + ER positive (1)
HER-2 amplification + ER positive + PGR negative (1)
HR negative + EGFR amplification (1)
HR positive + APOBEC signature (1)
HR positive + AURKA amplification (1)
HR positive + AURKA mutation (1)
HR positive + BRAF V600E (1)
HR positive + BRCA1 mutation + PALB2 mutation (1)
HR positive + BRCA2 mutation + PALB2 mutation (1)
HR positive + BRIP1 amplification (1)
HR positive + CCND1 amplification (1)
HR positive + HER-2 amplification (1)
HR positive + HER-2 mutation (1)
HR positive + MYC mutation (1)
HR positive + PIK3CA exon 10 mutation (1)
HR positive + PTEN deletion (1)
HR positive + RAD51C amplification (1)
HR positive + RB1 mutation (1)
HR positive + TMB-H (1)
HR positive + TMB-L (1)
High HDAC6 score + HR positive (1)
KRAS mutation + CDK9 overexpression + HR positive (1)
KRAS mutation + ER expression (1)
KRAS mutation + HR positive (1)
MTOR mutation + HR positive (1)
MYC mutation + ER positive (1)
PIK3CA E542K + HR positive (1)
PIK3CA amplification + PIK3CA mutation + HR positive (1)
PIK3CA exon 7 mutation + HR positive (1)
PIK3CA exon 9 mutation + HR positive (1)
PIK3CA mutation + ESR1 wild-type (1)
PIK3CA mutation + HR positive + HER-2 negative (1)
PIK3CA wild-type+ ESR1 wild-type (1)
PTEN deletion + ER positive (1)
PTEN mutation + HR positive (1)
TP53 wild-type + ER positive (1)
AKT1 E17K + CTNNB1 G34R + ER Y537S + MSI-H (0)
ER negative + HER-2 positive + PIK3CA H1047R (0)
ER positive + BRCA1 mutation (0)
ER positive + BRCA2 mutation (0)
ER positive + HER-2 negative + ER mutation (0)
HR positive + HER-2 negative + TMB-L (0)
PIK3CA mutation + ER negative + PGR positive (0)
›
Associations
(12)
News
Trials
Search handles
@ErikaHamilton9
@tmprowell
Search handles
@ErikaHamilton9
@tmprowell
Filter by
Latest
1year
Racial disparity in vitamin D status may explain racial disparity in survival from estrogen and progesterone receptor-positive breast cancer. Dr. William B. Grant PhD. @wbgrant2 Here is the link- https://t.co/uUyfPPhBLL (@Shahin75247020)
1 year ago
Grant
|
PGR (Progesterone receptor)
|
ER positive + PGR positive • PGR positive
almost2years
Racial disparity in vitamin D status may explain racial disparity in survival from estrogen and progesterone receptor-positive breast cancer. Dr. William B. Grant PhD. @wbgrant2 Here is the link- https://t.co/aWsk9YcphQ (@Lotus01394019)
almost 2 years ago
PGR (Progesterone receptor)
|
ER positive + PGR positive • PGR positive
over2years
Abema approved (monarchE trial) & PARPi for BRCA+ve pts from OlympiA in adj high risk pts: for ER/PR positive patients, clear sequencing, combo, or choosing one or the other rx remains unclear. What would you offer in your practice? #BCSM @ErikaHamilton9 @hoperugo @DrSGraff (@OncBrothers)
over 2 years ago
Clinical • European regulatory
|
PGR (Progesterone receptor) • BRCA (Breast cancer early onset)
|
ER positive + PGR positive • PGR positive
over2years
Dr. Cescon highlights large number of pts with PD at first scan. So...how do we do a better job figuring out who is endocrine resistant post CDK4/6....and then not keep on with ET? Positive ER/PR is NOT giving us the data. #bcsm #SABCS21 @OncoAlert (@ErikaHamilton9)
over 2 years ago
Clinical
|
CDK4 (Cyclin-dependent kinase 4)
|
ER positive + PGR positive
over2years
#SABCS21 #bcsm Dr. Pamela Goodwin presents MA.32, a RCT of #metformin vs placebo in early ER/PR positive or negative #breastcancer showing NO improvement in IDFS or OS. Metformin used for treatment of diabetes in people with BC remains acceptable. (People w/ DM were excluded.) (@tmprowell)
over 2 years ago
Clinical
|
PGR (Progesterone receptor)
|
ER positive + PGR positive • PGR positive
|
metformin
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