Login
Evidence Feed
About
Diagnostics
New
Top genes
FAQ
Contact us
^
Login
Contact us
to learn more about
our Premium Content: News alerts, weekly reports and conference planners
BIOMARKER:
EML4-ALK fusion
i
Other names:
EML4, EMAP Like 4, Restrictedly Overexpressed Proliferation-Associated Protein, Echinoderm Microtubule-Associated Protein-Like 4, Echinoderm Microtubule Associated Protein Like 4, Ropp 120, C2orf2, EMAP-4, EMAPL4, ROPP120, ELP120, NBLST3, CD246, Anaplastic Lymphoma Kinase, Anaplastic Lymphoma Kinase (Ki-1), CD246 Antigen, Mutant Anaplastic Lymphoma Kinase, ALK, ALK Receptor Tyrosine Kinase, Anaplastic Lymphoma Receptor Tyrosine Kinase, ALK Tyrosine Kinase Receptor
Contact us
to learn more about our Premium Content:
News alerts, weekly reports and conference planners
Entrez ID:
238
;
27436
Related biomarkers:
Expression
Mutation
CNA
Fusion
Others
‹
›
Associations
(27)
News
Trials
Search handles
@StephenVLiu
@SyedMAhmedMDPhD
@drjasonstarr
Search handles
@StephenVLiu
@SyedMAhmedMDPhD
@drjasonstarr
Filter by
Latest
9ms
Analysis of CROWN data (1L lorlatinib vs crizotinib) in #ALK NSCLC by EML4-ALK fusion variant and TP53 status @JTOonline. Given the clear biologic differences between variants (v3 vs others), I think it's time to stratify by variant and tailor strategies. https://t.co/iqJzIc5KEe (@StephenVLiu)
9 months ago
TP53 (Tumor protein P53) • EML4 (EMAP Like 4)
|
EML4-ALK fusion • ALK fusion
|
Xalkori (crizotinib) • Lorbrena (lorlatinib)
over1year
50s, EML4-ALK fusion, pdl1 30%, brain Mets on present. Started alectinib, favorable response. Cns only progression 1 y later tx SBRT, 3 m later wider brain progression and systemic progression. After WBRT? @JackWestMD @mjfidler @PatelOncology @LeciaSequist @ChristineBestv1 (@SyedMAhmedMDPhD)
over 1 year ago
PD-L1 (Programmed death ligand 1) • EML4 (EMAP Like 4)
|
EML4-ALK fusion • ALK fusion
|
Alecensa (alectinib)
2years
Atypical Lung Carcinoid With EML4/ALK Fusion Detected With Circulating Tumor DNA https://t.co/ozJcFGTCvC Should we be✅for genomic drivers in atypical lung carcinoid? Our case📖suggests maybe we should. @denisegococo @NANETS1 @CarcinoidNETs @netcanceraware @HealingNET1 @CureNETs (@drjasonstarr)
2 years ago
Circulating tumor DNA
|
EML4 (EMAP Like 4)
|
EML4-ALK fusion • ALK fusion
2years
Atypical Lung #Carcinoid With EML4/ALK Fusion Detected With Circulating Tumor DNA https://t.co/KrQovp1yB7 @drjasonstarr @NANETS1 @MayoClinic #NeuroendocrineTumors #LetsTalkAboutNETs (@CarcinoidNETs)
2 years ago
Circulating tumor DNA
|
EML4 (EMAP Like 4)
|
EML4-ALK fusion • ALK fusion
2years
Report in @ESMO_Open on liquid biopsy results post TKI therapy for 116 pts with #ALK fusion+ NSCLC. G1202R resistance mutation more common in EML4-ALK fusion variant 3, L1196M more in v1. More compound and complex mutations seen with use of multiple TKIs. https://t.co/ID201mkX4C (@StephenVLiu)
2 years ago
Clinical • Liquid biopsy
|
ALK (Anaplastic lymphoma kinase) • EML4 (EMAP Like 4)
|
EML4-ALK fusion • ALK fusion • ALK G1202R • EML4-ALK L1196M • ALK L1196M • EML4-ALK G1202R
Share
^
^
Full access to predictive biomarker details and heatmap analytics are available with a VERI Account.
Sign up for FREE
Already have an account?
Login
Full access to predictive biomarker details and heatmap analytics are available with a VERI Account.
Sign up for FREE
Already have an account?
Login