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BIOMARKER:
EGFR S768I
i
Other names:
EGFR, ERBB, ERBB1, Epidermal growth factor receptor
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Entrez ID:
1956
Related biomarkers:
Expression
Mutation
CNA
Fusion
Others
‹
EGFR expression (46)
EGFR overexpression (34)
EGFR positive (8)
EGFR negative (6)
EGFR negative + ALK negative (4)
EGFR expression + ALK positive (3)
EGFRVIII expression + PTEN expression (3)
EGFRvIII expression (3)
EGFR expression + MET expression (2)
EGFR overexpression + HER-2 overexpression (2)
MMP17 expression + EGFR expression + RB1 expression (2)
MUC1 expression + EGFR expression (2)
TROP2 expression + EGFR expression (2)
EGFR expression + HER-2 expression (1)
EGFR underexpression (1)
EGFRVIII overexpression (1)
EPHA2 overexpression + EGFR overexpression (1)
GPC3 positive + EGFR expression (1)
DRD2 expression + EGFR overexpression (0)
YAP1 overexpression + EGFR overexpression (0)
EGFR expression (46)
EGFR overexpression (34)
EGFR positive (8)
EGFR negative (6)
EGFR negative + ALK negative (4)
EGFR expression + ALK positive (3)
EGFRVIII expression + PTEN expression (3)
EGFRvIII expression (3)
EGFR expression + MET expression (2)
EGFR overexpression + HER-2 overexpression (2)
MMP17 expression + EGFR expression + RB1 expression (2)
MUC1 expression + EGFR expression (2)
TROP2 expression + EGFR expression (2)
EGFR expression + HER-2 expression (1)
EGFR underexpression (1)
EGFRVIII overexpression (1)
EPHA2 overexpression + EGFR overexpression (1)
GPC3 positive + EGFR expression (1)
DRD2 expression + EGFR overexpression (0)
YAP1 overexpression + EGFR overexpression (0)
›
Related tests:
therascreen® EGFR RGQ PCR Kit (5)
therascreen® EGFR RGQ PCR Kit (5)
Associations
(12)
News
Trials
Search handles
@APassaroMD
@BijoyTelivala
@DevikaDasMD
@esinghimd
Search handles
@APassaroMD
@BijoyTelivala
@DevikaDasMD
@esinghimd
Filter by
Latest
1year
2/ @LeXiuning @MDAndersonNews on EGFR mutations: ▪️EGFR mutations ~10-20% NSCLC pts in Europe/N America, & up to 50% of patients in Asia ▪️Exon 19 del & exon 21 L858R most common (~85-90%) ▪️🔑 Most frequent uncommon mutations to know: G719X, S768I, L861Q, & exon 20 insertions (@esinghimd)
1 year ago
Clinical
|
EGFR (Epidermal growth factor receptor)
|
EGFR mutation • EGFR L858R • EGFR exon 19 deletion • EGFR L861Q • EGFR G719X • EGFR S768I
over1year
Rare mutation question. What would be your front line choice for metastatic NSCLC adeno with EGFR S768I? #Lcsm @EGFRSummit @EGFRResisters @christine_lovly @AparGanti @CharuAggarwalMD @JackWestMD @dipeshuprety4 @HemOncWomenDocs (@DevikaDasMD)
over 1 year ago
EGFR (Epidermal growth factor receptor)
|
EGFR S768I
almost2years
I completely echo @DrSanjayPopat (tweet ⬆️)“Would suggest nil more,on t basis of data-everything else is conjecture. @myESMO EGFR expert consensus states “with…S768I in combo with non-common alterations, the use of osi cannot be recommended based on current efficacy data” #LCSM (@APassaroMD)
almost 2 years ago
Clinical
|
EGFR (Epidermal growth factor receptor)
|
EGFR S768I
over2years
For unresectable stage III NSCLC s/p chemo RT and a NGS revealing EGFR S768I ( or similar) would you? #lcsm @JackWestMD @PatelOncology @CharuAggarwalMD @LeciaSequist @HornLeora @benlevylungdoc @DrSteveMartin @BrunaPellini (@DevikaDasMD)
over 2 years ago
Next-generation sequencing
|
EGFR (Epidermal growth factor receptor)
|
EGFR S768I
almost3years
Need help with a #lungcancer patient 66 y/o F , non smoker Stage4- pleural effusion adenoca 2 EGFR mutations EXON 20 c.2303G>T (p.S768I) Exon 21: c.2573T>G (p.L858R) Tx options? Tagrisso? @PatelOncology @JackWestMD @HosseinBorghaei (@BijoyTelivala)
almost 3 years ago
Clinical • Pleural effusion
|
EGFR (Epidermal growth factor receptor)
|
EGFR mutation • EGFR L858R • EGFR S768I
|
Tagrisso (osimertinib)
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