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BIOMARKER:
EGFR L718Q
i
Other names:
EGFR, ERBB, ERBB1, Epidermal growth factor receptor
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News alerts, weekly reports and conference planners
Entrez ID:
1956
Related biomarkers:
Expression
Mutation
CNA
Fusion
Others
‹
EGFR expression (46)
EGFR overexpression (34)
EGFR positive (8)
EGFR negative (6)
EGFR negative + ALK negative (4)
EGFR expression + ALK positive (3)
EGFRVIII expression + PTEN expression (3)
EGFRvIII expression (3)
EGFR expression + MET expression (2)
EGFR overexpression + HER-2 overexpression (2)
MMP17 expression + EGFR expression + RB1 expression (2)
MUC1 expression + EGFR expression (2)
TROP2 expression + EGFR expression (2)
EGFR expression + HER-2 expression (1)
EGFR underexpression (1)
EGFRVIII overexpression (1)
EPHA2 overexpression + EGFR overexpression (1)
GPC3 positive + EGFR expression (1)
DRD2 expression + EGFR overexpression (0)
YAP1 overexpression + EGFR overexpression (0)
EGFR expression (46)
EGFR overexpression (34)
EGFR positive (8)
EGFR negative (6)
EGFR negative + ALK negative (4)
EGFR expression + ALK positive (3)
EGFRVIII expression + PTEN expression (3)
EGFRvIII expression (3)
EGFR expression + MET expression (2)
EGFR overexpression + HER-2 overexpression (2)
MMP17 expression + EGFR expression + RB1 expression (2)
MUC1 expression + EGFR expression (2)
TROP2 expression + EGFR expression (2)
EGFR expression + HER-2 expression (1)
EGFR underexpression (1)
EGFRVIII overexpression (1)
EPHA2 overexpression + EGFR overexpression (1)
GPC3 positive + EGFR expression (1)
DRD2 expression + EGFR overexpression (0)
YAP1 overexpression + EGFR overexpression (0)
›
Associations
(3)
News
Trials
Search handles
@StephenVLiu
Search handles
@StephenVLiu
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Latest
almost4years
#OncoAlert Report on a ph I/II trial of first line osimertinib + gefitinib in #EGFR NSCLC by Dr. Rotow. Will prevention of 2nd site mutations T790M, L718Q, C797S seen in vitro translate to more benefit? Report on 27 patients shows feasibility (though 11% G3 diarrhea). #OncoAlert (@StephenVLiu)
almost 4 years ago
EGFR (Epidermal growth factor receptor)
|
EGFR C797S • EGFR L718Q
|
Tagrisso (osimertinib) • gefitinib
almost4years
#OncoAlert Great correlatives to complement this trial including ctDNA analysis. Persistent detectable EGFR ctDNA at 6 weeks had worse PFS than those who cleared (9.8m vs 16.2m) and worse OS. Authors also characterized resistance (C797S, L718Q, squamous transformation). #LCSM (@StephenVLiu)
almost 4 years ago
EGFR (Epidermal growth factor receptor)
|
EGFR C797S • EGFR L718Q
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