Login
Evidence Feed
About
Diagnostics
New
Top genes
FAQ
Contact us
^
Login
Contact us
to learn more about
our Premium Content: News alerts, weekly reports and conference planners
DRUG:
sirexatamab (DKN-01)
i
Other names:
DKN-01, LY2812176, LY-2812176, DKN 01
Contact us
to learn more about our Premium Content:
News alerts, weekly reports and conference planners
Associations
(12)
News
Trials
Company:
BeiGene, Eli Lilly, Leap Therap
Drug class:
DKK1 protein inhibitor
Related drugs:
‹
BHQ880 (0)
BHQ880 (0)
›
Associations
(12)
News
Trials
Search handles
@MPishvaian
@ryanhuey
Search handles
@MPishvaian
@ryanhuey
Filter by
Latest
11ms
@giconnectInfo expert @KlempnerSam is presenting a poster at #ASCO23! A phase 2 study (DisTinGuish) of DKN-01 with #tislelizumab + chemotherapy as 1L therapy in pts w/ advanced gastric or GEJ adenocarcinoma. https://t.co/I7mVGdWU9Z Abstract 4027, 5/6 11:30 Hall D2 #MedEd (@giconnectInfo)
11 months ago
Clinical • Metastases
|
Tevimbra (tislelizumab) • sirexatamab (DKN-01)
over2years
DisTinGuish Trial: DKN-01 + tislelizumab +/- chemo as 1L/2L GEA. Seems to be a signal in DKK1+ patients (who have an aggressive phenotype). #GI22 abstract 292 @KlempnerSam (@ryanhuey)
over 2 years ago
Clinical
|
DKK1 (dickkopf WNT signaling pathway inhibitor 1)
|
Tevimbra (tislelizumab) • sirexatamab (DKN-01)
over2years
#GI22 4⃣/ ✅G/E/GEJ ➡️@KlempnerSam Abs 292 ⏩DisTinGuish Trial ⏩DKN-01➕tisleliz +/- chemo in advanced GEA 🧑🏫(DKN-01 is an anti-DKK1 mAb) ⏩49 pts 👉100% ORR in the 12 DKK-1 High patients‼️ (@MPishvaian)
over 2 years ago
Clinical
|
DKK1 (dickkopf WNT signaling pathway inhibitor 1)
|
sirexatamab (DKN-01)
Share
^
^
Full access to predictive biomarker details and heatmap analytics are available with a VERI Account.
Sign up for FREE
Already have an account?
Login
Full access to predictive biomarker details and heatmap analytics are available with a VERI Account.
Sign up for FREE
Already have an account?
Login