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BIOMARKER:
CRLF2 rearrangement
i
Other names:
CRLF2, Cytokine Receptor Like Factor 2, Thymic Stromal Lymphopoietin Protein Receptor, Cytokine Receptor-Like Factor 2, TSLP Receptor, IL-XR, TSLPR, CRL2, Thymic Stromal-Derived Lymphopoietin Receptor, Cytokine Receptor CRL2 Precusor, Cytokine Receptor-Like 2, CRLF2Y, ILXR
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Entrez ID:
64109
Related biomarkers:
Expression
Mutation
Fusion
Others
‹
›
Associations
(4)
News
Trials
Search handles
@FadiHaddad_MD
@NitinJainMD
@syed_abutalibmd
Search handles
@FadiHaddad_MD
@NitinJainMD
@syed_abutalibmd
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Latest
1year
Just out from our group 📣📣Improved outcomes of relapsed/refractory CRLF2-rearranged ALL with the use of targeted therapies! @DrHKantarjian @NitinJainMD @DesikanSai @jayastuMD @NicholasShortMD @MDAndersonNews #leusm #MedTwitter #leukemia #endcancer (@FadiHaddad_MD)
1 year ago
CRLF2 (Cytokine Receptor Like Factor 2)
|
CRLF2 rearrangement
2years
Great summary! @AaronGoodman33 One addition for JAK2 mutation JAK2 R683G = Ph-like ALL (~50% of CRLF2 rearranged ALL, a subset of Ph-like ALL have JAK2 mutation, most commonly R683G, never V617F) And yes JAK fusions can also occur in Ph-like ALL #leusm (@NitinJainMD)
2 years ago
JAK2 (Janus kinase 2) • CRLF2 (Cytokine Receptor Like Factor 2)
|
CRLF2 rearrangement • JAK2 V617F • JAK2 mutation • JAK2 R683G
over2years
Excited to see our collaborative work on the “Degradation of Janus kinases in CRLF2-rearranged acute lymphoblastic leukemia” appear as a Plenary Paper in @BloodJournal with @CMullighan and #stjuderesearch CBT Chemistry Centers. https://t.co/swBfzXbFAE (@TheFischerLab)
over 2 years ago
CRLF2 (Cytokine Receptor Like Factor 2)
|
CRLF2 rearrangement
over2years
Combination efficacy of ruxolitinib with standard-of-care drugs in CRLF2-rearranged Ph-like acute lymphoblastic leukemia | Leukemia https://t.co/nPCFmqmE5M (@syed_abutalibmd)
over 2 years ago
Clinical
|
CRLF2 (Cytokine Receptor Like Factor 2)
|
CRLF2 rearrangement
|
Jakafi (ruxolitinib)
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