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DRUG CLASS:

cRAF inhibitor

9ms
BRAF (B-raf proto-oncogene)
|
BRAF V600E • BRAF V600
|
Mektovi (binimetinib) • Braftovi (encorafenib)
over1year
KRAS (KRAS proto-oncogene GTPase) • RAF1 (Raf-1 Proto-Oncogene Serine/Threonine Kinase)
|
KRAS wild-type • RAS wild-type • KRAS G12
over2years
PD-L1 (Programmed death ligand 1) • KRAS (KRAS proto-oncogene GTPase) • RAF1 (Raf-1 Proto-Oncogene Serine/Threonine Kinase)
|
KRAS G12V • KRAS G12
|
avutometinib (VS-6766)
almost3years
Clinical
|
KRAS (KRAS proto-oncogene GTPase) • RAF1 (Raf-1 Proto-Oncogene Serine/Threonine Kinase)
|
KRAS G12
|
avutometinib (VS-6766) • defactinib (VS-6063)
over3years
RAF1 (Raf-1 Proto-Oncogene Serine/Threonine Kinase)
|
avutometinib (VS-6766) • SCH772984 • VS-5584