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BIOMARKER:
CDKN2A deletion
i
Other names:
CDKN2A, ARF, CDK4I, CDKN2, CMM2, INK4, INK4a, MLM, MTS1, p14, p14ARF, p16, p16INK4a, p19, p19Arf, Cyclin-dependent kinase inhibitor 2A
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Entrez ID:
1029
Related biomarkers:
Expression
Mutation
CNA
Others
‹
CDKN2A promoter methylation (2)
ALK rearrangement + CDKN2A deletion (1)
BAP1 mutation + IDH2 R172W + CDKN2A deletion + CDKN2B deletion (1)
BRAF V600E + CDKN2A deletion + MYCN amplification (1)
BRAF V600E + CDKN2A deletion + RB1 expression (1)
BRAF V600K + CDKN2A deletion + RB1 expression (1)
CDKN2A Negative + NRAS Mutation (1)
CDKN2A deletion + CDKN2B deletion + MTAP deletion + TERT mutation (1)
CDKN2A mutation + PD-L1 overexpression (1)
CDKN2A mutation + TMB-H (1)
EGFR mutation + CCND1 expression + CDKN2A deletion (1)
NF1 mutation + CDKN2A deletion + CDKN2B deletion + MTAP deletion (1)
TMB-L + ARID1A deletion + CDKN2A deletion + CDKN2B deletion + MTAP deletion + PIK3R1 N564D + NBN P81fs*23 (1)
CDKN2A promoter methylation (2)
ALK rearrangement + CDKN2A deletion (1)
BAP1 mutation + IDH2 R172W + CDKN2A deletion + CDKN2B deletion (1)
BRAF V600E + CDKN2A deletion + MYCN amplification (1)
BRAF V600E + CDKN2A deletion + RB1 expression (1)
BRAF V600K + CDKN2A deletion + RB1 expression (1)
CDKN2A Negative + NRAS Mutation (1)
CDKN2A deletion + CDKN2B deletion + MTAP deletion + TERT mutation (1)
CDKN2A mutation + PD-L1 overexpression (1)
CDKN2A mutation + TMB-H (1)
EGFR mutation + CCND1 expression + CDKN2A deletion (1)
NF1 mutation + CDKN2A deletion + CDKN2B deletion + MTAP deletion (1)
TMB-L + ARID1A deletion + CDKN2A deletion + CDKN2B deletion + MTAP deletion + PIK3R1 N564D + NBN P81fs*23 (1)
›
Associations
(20)
News
Trials
Search handles
@weldeiry
Search handles
@weldeiry
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Latest
almost2years
Pleomorphic xanthoastrocytoma. BRAF mutation and homozygous CDKN2A and/or B deletion. (@GustavoGaravag4)
almost 2 years ago
BRAF (B-raf proto-oncogene) • CDKN2A (Cyclin Dependent Kinase Inhibitor 2A)
|
BRAF mutation • CDKN2A deletion • CDKN2A mutation
almost2years
Sharing research @BrownUCancer with @BrownMedicine med student Taylor Arnoff MDM2/MDM4 amplification and CDKN2A deletion in metastatic melanoma and glioblastoma multiforme may have implications for targeted therapeutics & immunotherapy https://t.co/1NBaURjiyo (@weldeiry)
almost 2 years ago
CDKN2A (Cyclin Dependent Kinase Inhibitor 2A) • MDM2 (E3 ubiquitin protein ligase) • MDM4 (The mouse double minute 4)
|
CDKN2A deletion • MDM4 amplification
almost2years
Happy to share our latest research: MDM2/MDM4 amplification and CDKN2A deletion in metastatic melanoma and glioblastoma multiforme may have implications for targeted therapeutics and immunotherapy https://t.co/l0Q2QWiO6Z #eldeirylab @BrownUCancer @BrownMedicine @BrownUniversity (@weldeiry)
almost 2 years ago
CDKN2A (Cyclin Dependent Kinase Inhibitor 2A) • MDM2 (E3 ubiquitin protein ligase) • MDM4 (The mouse double minute 4)
|
CDKN2A deletion • MDM4 amplification
2years
IDH mutant astrocytoma . need to do NGS and DNA methylation profile to look for CDKN2A homozygos deletion or other specific alterations. (@RawiaMo57385655)
2 years ago
Next-generation sequencing • Epigenetic controller
|
CDKN2A (Cyclin Dependent Kinase Inhibitor 2A)
|
CDKN2A deletion
almost3years
I’m a colon cancer patient with a CDKN2A deep deletion. I’m not sure what deep deletion means. This isn’t a germline mutation, but from the tumor. An Ibrance trial came up on the paper with the results. Have you heard of colon cancer patients with peri mets using ibrance? (@SSpitalny)
almost 3 years ago
Clinical
|
CDKN2A (Cyclin Dependent Kinase Inhibitor 2A)
|
CDKN2A deletion
|
Ibrance (palbociclib)
over3years
What Is the Role of CDKN2A/B Homozygous Deletion in IDH–Mutant Astrocytoma? Dr. Sani H. Kizilbash answers in-depth for #ASCODailyNews https://t.co/9d4MtW0szA #BTSM (@ASCO)
over 3 years ago
CDKN2A (Cyclin Dependent Kinase Inhibitor 2A) • CDKN2B (Cyclin Dependent Kinase Inhibitor 2B)
|
CDKN2A deletion
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