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BIOMARKER:
CD73 overexpression
i
Other names:
CD73, 5'-Nucleotidase Ecto, Ecto-5'-Nucleotidase, 5'-Nucleotidase, 5'-NT, NT5, NTE, 5'-Nucleotidase, Ecto (CD73), Purine 5-Prime-Nucleotidase, 5' Nucleotidase (CD73), CD73 Antigen, E5NT
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Entrez ID:
4907
Related biomarkers:
Expression
Others
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Associations
(6)
News
Trials
Search handles
@StephenVLiu
Search handles
@StephenVLiu
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Latest
over1year
Report of oleclumab (anti-CD73) plus osimertinib in #EGFR NSCLC @JTOonline. CD73 often overexpressed in EGFR mutant NSCLC. Explored post 1G/2G TKI, T790M negative, osi naive. At dose level 2, RR 12% with mPFS 7.4m, mOS 25m. https://t.co/we5zEtPi4r (@StephenVLiu)
over 1 year ago
EGFR (Epidermal growth factor receptor)
|
EGFR mutation • EGFR T790M • EGFR overexpression • CD73 overexpression • EGFR T790M negative • CD73 expression
|
Tagrisso (osimertinib) • oleclumab (MEDI9447)
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