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BIOMARKER:
BRCA2 positive
i
Other names:
BRCA2, BRCC2, FACD, FAD, FAD1, FANCD, FANCD1, Breast cancer 2, early onset
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Entrez ID:
675
Related biomarkers:
Expression
Mutation
CNA
Fusion
Others
‹
HRD + BRCA2 mutation (7)
BRCA2 mutation + HR positive (3)
HR positive + BRCA2 mutation (3)
BRCA2 mutation + HER-2 negative (2)
HR negative + BRCA2 mutation (2)
ALK rearrangement + BRCA2 F2801fs (1)
BRCA1 mutation + BRCA2 mutation + TMB-H (1)
BRCA2 deletion + ATM mutation (1)
BRCA2 mutation + AKR1C3 overexpression (1)
BRCA2 mutation + ER positive (1)
BRCA2 mutation + ER positive + PGR positive (1)
BRCA2 mutation + RB1 deletion (1)
BRCA2 mutation + TMB-H (1)
BRCA2 mutation + TMB-L (1)
HR positive + BRCA2 mutation + PALB2 mutation (1)
ER positive + BRCA2 mutation (0)
HRD + BRCA2 mutation (7)
BRCA2 mutation + HR positive (3)
HR positive + BRCA2 mutation (3)
BRCA2 mutation + HER-2 negative (2)
HR negative + BRCA2 mutation (2)
ALK rearrangement + BRCA2 F2801fs (1)
BRCA1 mutation + BRCA2 mutation + TMB-H (1)
BRCA2 deletion + ATM mutation (1)
BRCA2 mutation + AKR1C3 overexpression (1)
BRCA2 mutation + ER positive (1)
BRCA2 mutation + ER positive + PGR positive (1)
BRCA2 mutation + RB1 deletion (1)
BRCA2 mutation + TMB-H (1)
BRCA2 mutation + TMB-L (1)
HR positive + BRCA2 mutation + PALB2 mutation (1)
ER positive + BRCA2 mutation (0)
›
Associations
(1)
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Latest
11ms
After being diagnosed with breast and pancreatic cancer, Betty Dicker, a BRCA2 positive patient of Dr. Diane M. Simeone (@MadameSimeone) and Dr. Paul Oberstein (@MD_Oberstein), shares her survivorship journey with @ASCOPost. #ASCO23 Read her story: https://t.co/4qFe7Hct65 (@Perlmutter_CC)
11 months ago
Clinical
|
BRCA2 (Breast cancer 2, early onset)
|
BRCA2 positive
over2years
@JenniferLitton discusses the rationale for examining neoadjuvant talazoparib in patients with BRCA1/2-positive, early HER2-negative breast cancer, safety and efficacy results from NEOTALA, and next steps for research. @MDAndersonNews #bcsm https://t.co/6s87V37LgT (@OncLive)
over 2 years ago
Clinical
|
HER-2 (Human epidermal growth factor receptor 2) • BRCA1 (Breast cancer 1, early onset) • BRCA2 (Breast cancer 2, early onset)
|
HER-2 negative • BRCA1 positive • BRCA2 positive
|
Talzenna (talazoparib)
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