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BIOMARKER:
BRCA1 positive
i
Other names:
BRCA1, BRCC1, PPP1R53, RNF53, Breast cancer 1, early onset
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Entrez ID:
672
Related biomarkers:
Expression
Mutation
CNA
Fusion
Others
‹
BRCA1 mutation (196)
BRCA wild-type (19)
BRCA1 2110_2111delAA + BRCA1 4071_4096 +14del40 + TP53 R342P + NOTCH2 Q1310H (7)
BRCA1 mutation + BRCA2 mutation (4)
BRCA1 L1780P (2)
BRCA1 R1443* (2)
BRCA1 mutation + TP53 mutation (2)
EGFR mutation + TP53 mutation + BRCA1 mutation (2)
BRCA1 2080delA (1)
BRCA1 307 T> A (L63*) (1)
BRCA1 3363delGAAA (1)
BRCA1 5396insC (1)
BRCA1 E1446* (1)
BRCA1 N1018fs*8 (1)
BRCA1 Q858 (1)
BRCA1 S451Lfs*20 (1)
BRCA1 biallelic inactivation (1)
BRCA1 mutation + ATM mutation (1)
BRCA1 mutation + TP53 R248Q (1)
BRCA1 rearrangement (1)
MSH2 mutation + MSH6 mutation + BRCA1 mutation (1)
BRCA1 mutation (196)
BRCA wild-type (19)
BRCA1 2110_2111delAA + BRCA1 4071_4096 +14del40 + TP53 R342P + NOTCH2 Q1310H (7)
BRCA1 mutation + BRCA2 mutation (4)
BRCA1 L1780P (2)
BRCA1 R1443* (2)
BRCA1 mutation + TP53 mutation (2)
EGFR mutation + TP53 mutation + BRCA1 mutation (2)
BRCA1 2080delA (1)
BRCA1 307 T> A (L63*) (1)
BRCA1 3363delGAAA (1)
BRCA1 5396insC (1)
BRCA1 E1446* (1)
BRCA1 N1018fs*8 (1)
BRCA1 Q858 (1)
BRCA1 S451Lfs*20 (1)
BRCA1 biallelic inactivation (1)
BRCA1 mutation + ATM mutation (1)
BRCA1 mutation + TP53 R248Q (1)
BRCA1 rearrangement (1)
MSH2 mutation + MSH6 mutation + BRCA1 mutation (1)
›
Associations
(2)
News
Trials
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Latest
2years
My grandma, my mom, my aunt & my cousin only 41, all passed away from breast cancer. Diagnose stage 4 Inflammatory BC at 45. My mom didn’t want to be tested. I did the BRCA1/BRCA2 gene test, I’m BRCA1 positive. I could of been saved if I known this earlier.🤬 (@Thinkpin2018)
2 years ago
BRCA1 (Breast cancer 1, early onset) • BRCA2 (Breast cancer 2, early onset)
|
BRCA1 positive
over2years
@DrAhmedAlShehri دكتور أحمد .. اذا كانت المريضة عمرها ٢٦ و هي BRCA 1 positive و امها جاها breast cancer في عمر اقل من ٤٥ و الحين اكتشفوا عندها nodule circumscribed sized 1.3*0.5 cm What will be the plan of treatment? (@soul_taichi)
over 2 years ago
BRCA1 (Breast cancer 1, early onset) • BRCA (Breast cancer early onset)
|
BRCA1 positive
over2years
@JenniferLitton discusses the rationale for examining neoadjuvant talazoparib in patients with BRCA1/2-positive, early HER2-negative breast cancer, safety and efficacy results from NEOTALA, and next steps for research. @MDAndersonNews #bcsm https://t.co/6s87V37LgT (@OncLive)
over 2 years ago
Clinical
|
HER-2 (Human epidermal growth factor receptor 2) • BRCA1 (Breast cancer 1, early onset) • BRCA2 (Breast cancer 2, early onset)
|
HER-2 negative • BRCA1 positive • BRCA2 positive
|
Talzenna (talazoparib)
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