Login
Evidence Feed
About
Diagnostics
New
Top genes
FAQ
Contact us
^
Login
Contact us
to learn more about
our Premium Content: News alerts, weekly reports and conference planners
BIOMARKER:
BRCA1 mutation + BRCA2 mutation
i
Other names:
BRCA2, BRCC2, FACD, FAD, FAD1, FANCD, FANCD1, Breast cancer 2, early onset, BRCA1, BRCC1, PPP1R53, RNF53, Breast cancer 1, early onset
Contact us
to learn more about our Premium Content:
News alerts, weekly reports and conference planners
Entrez ID:
672
;
675
Related biomarkers:
Expression
Mutation
CNA
Fusion
Others
‹
HRD + BRCA1 mutation (7)
HRD + BRCA2 mutation (7)
BRCA1 mutation + HR positive (3)
BRCA1 mutation + TMB-H (3)
BRCA2 mutation + HR positive (3)
HR positive + BRCA2 mutation (3)
BRCA1 2080delA + CCNE1 overexpression (2)
BRCA1 mutation + HER-2 negative (2)
HR negative + BRCA1 mutation (2)
HR positive + BRCA1 mutation (2)
BRCA2 mutation + HER-2 negative (2)
HR negative + BRCA2 mutation (2)
BAP1 negative + BRCA1 mutation (1)
BRCA1 hypermethylation (1)
BRCA1 mutation + AKR1C3 overexpression (1)
BRCA1 mutation + BRCA2 mutation + TMB-H (1)
BRCA1 mutation + HER-2 negative + ER positive + PGR positive (1)
BRCA1 mutation + PD-L1 expression (1)
BRCA1 mutation + RAD51B deletion (1)
BRCA1 mutation + RB1 deletion (1)
BRCA1 promoter methylation (1)
EGFR mutation + BRCA1 overexpression (1)
EGFR mutation + BRCA1 underexpression (1)
HR positive + BRCA1 mutation + PALB2 mutation (1)
PTEN deletion + BRCA1 mutation (1)
ALK rearrangement + BRCA2 F2801fs (1)
BRCA2 deletion + ATM mutation (1)
BRCA2 mutation + AKR1C3 overexpression (1)
BRCA2 mutation + ER positive (1)
BRCA2 mutation + ER positive + PGR positive (1)
BRCA2 mutation + RB1 deletion (1)
BRCA2 mutation + TMB-H (1)
BRCA2 mutation + TMB-L (1)
HR positive + BRCA2 mutation + PALB2 mutation (1)
ER positive + BRCA1 mutation (0)
ER positive + BRCA2 mutation (0)
HRD + BRCA1 mutation (7)
HRD + BRCA2 mutation (7)
BRCA1 mutation + HR positive (3)
BRCA1 mutation + TMB-H (3)
BRCA2 mutation + HR positive (3)
HR positive + BRCA2 mutation (3)
BRCA1 2080delA + CCNE1 overexpression (2)
BRCA1 mutation + HER-2 negative (2)
HR negative + BRCA1 mutation (2)
HR positive + BRCA1 mutation (2)
BRCA2 mutation + HER-2 negative (2)
HR negative + BRCA2 mutation (2)
BAP1 negative + BRCA1 mutation (1)
BRCA1 hypermethylation (1)
BRCA1 mutation + AKR1C3 overexpression (1)
BRCA1 mutation + BRCA2 mutation + TMB-H (1)
BRCA1 mutation + HER-2 negative + ER positive + PGR positive (1)
BRCA1 mutation + PD-L1 expression (1)
BRCA1 mutation + RAD51B deletion (1)
BRCA1 mutation + RB1 deletion (1)
BRCA1 promoter methylation (1)
EGFR mutation + BRCA1 overexpression (1)
EGFR mutation + BRCA1 underexpression (1)
HR positive + BRCA1 mutation + PALB2 mutation (1)
PTEN deletion + BRCA1 mutation (1)
ALK rearrangement + BRCA2 F2801fs (1)
BRCA2 deletion + ATM mutation (1)
BRCA2 mutation + AKR1C3 overexpression (1)
BRCA2 mutation + ER positive (1)
BRCA2 mutation + ER positive + PGR positive (1)
BRCA2 mutation + RB1 deletion (1)
BRCA2 mutation + TMB-H (1)
BRCA2 mutation + TMB-L (1)
HR positive + BRCA2 mutation + PALB2 mutation (1)
ER positive + BRCA1 mutation (0)
ER positive + BRCA2 mutation (0)
›
Associations
(4)
News
Trials
Search handles
@0109Ayumi
@BenWestphalen
@jamecancerdoc
Search handles
@0109Ayumi
@BenWestphalen
@jamecancerdoc
Filter by
Latest
over1year
Association of location of BRCA1 and BRCA2 mutations with benefit from olaparib and bevacizumab maintenance in high-grade ovarian cancer: Phase III PAOLA-1/ENGOT-ov25 trial subgroup exploratory analysis - ScienceDirect https://t.co/JyiMoQ8qGH (@0109Ayumi)
over 1 year ago
Clinical
|
BRCA1 (Breast cancer 1, early onset) • BRCA2 (Breast cancer 2, early onset)
|
BRCA2 mutation • BRCA1 mutation • BRCA1 mutation + BRCA2 mutation
|
Avastin (bevacizumab) • Lynparza (olaparib)
over2years
Olaparib in early #breastcancer Excellent practical Q/A tips - for Germline BRCA1 and/or BRCA2 Mutation Carriers https://t.co/8OlrKzCsXo @JCOOP_ASCO @ASCO @OncoAlert (@jamecancerdoc)
over 2 years ago
BRCA1 (Breast cancer 1, early onset) • BRCA2 (Breast cancer 2, early onset)
|
BRCA2 mutation • BRCA1 mutation • BRCA1 mutation + BRCA2 mutation
|
Lynparza (olaparib)
over2years
@Priyabhard of @WeillCornellGS is an #SABCS21 Basic Science Scholar for "Obesity is associated with DNA damage in the breast epithelium of BRCA1 and BRCA2 mutation carriers: A role for estrogens & strategies for prevention," P2-06-03 Wednesday, Dec. 8, 5 p.m. #meetthescholars (@SABCSSanAntonio)
over 2 years ago
BRCA1 (Breast cancer 1, early onset) • BRCA2 (Breast cancer 2, early onset)
|
BRCA2 mutation • BRCA1 mutation • BRCA1 mutation + BRCA2 mutation
over3years
Interesting manuscript on >2800 #pancsm patients in @myESMO @ESMO_Open : 124 patients (4,2%) carried a mutation in BRCA1/2 or PALB2. Mut were associated w distinct mol profile potentially predictive for response to ICI. @weldeiry @agrothey @OncoAlert 🚨 https://t.co/dZXWP9JR5f (@BenWestphalen)
over 3 years ago
Clinical • BRCA Biomarker
|
BRCA1 (Breast cancer 1, early onset) • BRCA2 (Breast cancer 2, early onset) • PALB2 (Partner and localizer of BRCA2)
|
BRCA2 mutation • BRCA1 mutation • PALB2 mutation • BRCA1 mutation + BRCA2 mutation
over3years
Good news: #PARP inhibition is an effective treatment for patients with metastatic #BreastCancer and gPALB2 or sBRCA1/2 mutations @OncoAlert @ASCO_pubs @judygarber5 @DrEricWiner #bcsm #OncoAlert https://t.co/Z2uRxVXUbb (@AlexTihonoff)
over 3 years ago
Clinical • BRCA Biomarker • PARP Biomarker
|
BRCA1 (Breast cancer 1, early onset) • BRCA2 (Breast cancer 2, early onset)
|
BRCA2 mutation • BRCA1 mutation • PALB2 mutation • BRCA1 mutation + BRCA2 mutation
Share
^
^
Full access to predictive biomarker details and heatmap analytics are available with a VERI Account.
Sign up for FREE
Already have an account?
Login
Full access to predictive biomarker details and heatmap analytics are available with a VERI Account.
Sign up for FREE
Already have an account?
Login