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BIOMARKER:
BRCA1 mutation + BRCA2 mutation
i
Other names:
BRCA2, BRCC2, FACD, FAD, FAD1, FANCD, FANCD1, Breast cancer 2, early onset, BRCA1, BRCC1, PPP1R53, RNF53, Breast cancer 1, early onset
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News alerts, weekly reports and conference planners
Entrez ID:
672
;
675
Related biomarkers:
Expression
Mutation
CNA
Fusion
Others
‹
BRCA1 expression (3)
BRCA1 positive (2)
BRCA1 underexpression (2)
BRCA2 overexpression (2)
BRCA1 negative (1)
BRCA2 expression (1)
BRCA2 positive (1)
BRCA2 underexpression (1)
BRCA1 expression (3)
BRCA1 positive (2)
BRCA1 underexpression (2)
BRCA2 overexpression (2)
BRCA1 negative (1)
BRCA2 expression (1)
BRCA2 positive (1)
BRCA2 underexpression (1)
›
Associations
(4)
News
Trials
Search handles
@0109Ayumi
@BenWestphalen
@jamecancerdoc
Search handles
@0109Ayumi
@BenWestphalen
@jamecancerdoc
Filter by
Latest
over1year
Association of location of BRCA1 and BRCA2 mutations with benefit from olaparib and bevacizumab maintenance in high-grade ovarian cancer: Phase III PAOLA-1/ENGOT-ov25 trial subgroup exploratory analysis - ScienceDirect https://t.co/JyiMoQ8qGH (@0109Ayumi)
over 1 year ago
Clinical
|
BRCA1 (Breast cancer 1, early onset) • BRCA2 (Breast cancer 2, early onset)
|
BRCA2 mutation • BRCA1 mutation • BRCA1 mutation + BRCA2 mutation
|
Avastin (bevacizumab) • Lynparza (olaparib)
over2years
Olaparib in early #breastcancer Excellent practical Q/A tips - for Germline BRCA1 and/or BRCA2 Mutation Carriers https://t.co/8OlrKzCsXo @JCOOP_ASCO @ASCO @OncoAlert (@jamecancerdoc)
over 2 years ago
BRCA1 (Breast cancer 1, early onset) • BRCA2 (Breast cancer 2, early onset)
|
BRCA2 mutation • BRCA1 mutation • BRCA1 mutation + BRCA2 mutation
|
Lynparza (olaparib)
over2years
@Priyabhard of @WeillCornellGS is an #SABCS21 Basic Science Scholar for "Obesity is associated with DNA damage in the breast epithelium of BRCA1 and BRCA2 mutation carriers: A role for estrogens & strategies for prevention," P2-06-03 Wednesday, Dec. 8, 5 p.m. #meetthescholars (@SABCSSanAntonio)
over 2 years ago
BRCA1 (Breast cancer 1, early onset) • BRCA2 (Breast cancer 2, early onset)
|
BRCA2 mutation • BRCA1 mutation • BRCA1 mutation + BRCA2 mutation
over3years
Interesting manuscript on >2800 #pancsm patients in @myESMO @ESMO_Open : 124 patients (4,2%) carried a mutation in BRCA1/2 or PALB2. Mut were associated w distinct mol profile potentially predictive for response to ICI. @weldeiry @agrothey @OncoAlert 🚨 https://t.co/dZXWP9JR5f (@BenWestphalen)
over 3 years ago
Clinical • BRCA Biomarker
|
BRCA1 (Breast cancer 1, early onset) • BRCA2 (Breast cancer 2, early onset) • PALB2 (Partner and localizer of BRCA2)
|
BRCA2 mutation • BRCA1 mutation • PALB2 mutation • BRCA1 mutation + BRCA2 mutation
over3years
Good news: #PARP inhibition is an effective treatment for patients with metastatic #BreastCancer and gPALB2 or sBRCA1/2 mutations @OncoAlert @ASCO_pubs @judygarber5 @DrEricWiner #bcsm #OncoAlert https://t.co/Z2uRxVXUbb (@AlexTihonoff)
over 3 years ago
Clinical • BRCA Biomarker • PARP Biomarker
|
BRCA1 (Breast cancer 1, early onset) • BRCA2 (Breast cancer 2, early onset)
|
BRCA2 mutation • BRCA1 mutation • PALB2 mutation • BRCA1 mutation + BRCA2 mutation
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