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BIOMARKER:
BRCA1 expression
i
Other names:
BRCA1, BRCC1, PPP1R53, RNF53, Breast cancer 1, early onset
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Entrez ID:
672
Related biomarkers:
Expression
Mutation
CNA
Fusion
Others
‹
HRD + BRCA1 mutation (7)
BRCA1 mutation + HR positive (3)
BRCA1 mutation + TMB-H (3)
BRCA1 2080delA + CCNE1 overexpression (2)
BRCA1 mutation + HER-2 negative (2)
HR negative + BRCA1 mutation (2)
HR positive + BRCA1 mutation (2)
BAP1 negative + BRCA1 mutation (1)
BRCA1 hypermethylation (1)
BRCA1 mutation + AKR1C3 overexpression (1)
BRCA1 mutation + BRCA2 mutation + TMB-H (1)
BRCA1 mutation + HER-2 negative + ER positive + PGR positive (1)
BRCA1 mutation + PD-L1 expression (1)
BRCA1 mutation + RAD51B deletion (1)
BRCA1 mutation + RB1 deletion (1)
BRCA1 promoter methylation (1)
EGFR mutation + BRCA1 overexpression (1)
EGFR mutation + BRCA1 underexpression (1)
HR positive + BRCA1 mutation + PALB2 mutation (1)
PTEN deletion + BRCA1 mutation (1)
ER positive + BRCA1 mutation (0)
HRD + BRCA1 mutation (7)
BRCA1 mutation + HR positive (3)
BRCA1 mutation + TMB-H (3)
BRCA1 2080delA + CCNE1 overexpression (2)
BRCA1 mutation + HER-2 negative (2)
HR negative + BRCA1 mutation (2)
HR positive + BRCA1 mutation (2)
BAP1 negative + BRCA1 mutation (1)
BRCA1 hypermethylation (1)
BRCA1 mutation + AKR1C3 overexpression (1)
BRCA1 mutation + BRCA2 mutation + TMB-H (1)
BRCA1 mutation + HER-2 negative + ER positive + PGR positive (1)
BRCA1 mutation + PD-L1 expression (1)
BRCA1 mutation + RAD51B deletion (1)
BRCA1 mutation + RB1 deletion (1)
BRCA1 promoter methylation (1)
EGFR mutation + BRCA1 overexpression (1)
EGFR mutation + BRCA1 underexpression (1)
HR positive + BRCA1 mutation + PALB2 mutation (1)
PTEN deletion + BRCA1 mutation (1)
ER positive + BRCA1 mutation (0)
›
Associations
(3)
News
Trials
Search handles
@Dr_Ivanoncologo
@cancerassassin1
@weldeiry
Search handles
@Dr_Ivanoncologo
@cancerassassin1
@weldeiry
Filter by
Latest
almost2years
Have read some data suggesting correlation b/w ⬇️ Vit D & breast cancer, not TNBC specific. Also, could you provide more detail about “p53 functions which trigger eventual BRCA1 expression?” Research articles/study links? Thanks! (@JaniceTNBCmets)
almost 2 years ago
BRCA1 (Breast cancer 1, early onset)
|
BRCA1 expression
almost2years
Significant vitamin d deficiency at dx and prior five years super common in my clients w/TNBC sans BRCA1 mutation. VDR needed for important P53 functions which trigger eventual BRCA1 expression. Sure wish we could know D levels in the controls that respond to PARPi. Low? (@nursekristinrn)
almost 2 years ago
BRCA1 (Breast cancer 1, early onset)
|
TP53 mutation • BRCA1 mutation • BRCA1 expression
almost2years
An interesting study shows that patients with mt KRAS #NSCLC could benefit from a #KRAS-targeted treatment strategy in combination with #therapeutic agents based on #markers such as #SRC and #BRCA1 expression levels. @LungCancerDr @Lungsolutions https://t.co/9SKipnlcA6 (@Dr_Ivanoncologo)
almost 2 years ago
Clinical • Combination therapy
|
KRAS (KRAS proto-oncogene GTPase) • BRCA1 (Breast cancer 1, early onset)
|
BRCA1 expression
over2years
Original paper in @Oncotarget from Leaf et al @weldeiry lab: Opposing effects of BRCA1 mRNA expression on patient survival in breast and colorectal cancer and variations among African American, Asian, and younger patients https://t.co/duCkThZ2s7 #bcsm #crcsm #healthdisparities (@cancerassassin1)
over 2 years ago
Clinical
|
BRCA1 (Breast cancer 1, early onset)
|
BRCA1 expression
over2years
News Release @Oncotarget: BRCA1 mRNA expression in breast and colorectal cancer https://t.co/ste3sae9zi #eldeirylab @BrownMedicine @BrownUCancer @BrownPathology @BrownUniversity @BrownUPathoGP (@weldeiry)
over 2 years ago
BRCA1 (Breast cancer 1, early onset)
|
BRCA1 expression
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