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BIOMARKER:
BRAF K601E
i
Other names:
BRAF, B-raf proto-oncogene, B-raf proto-oncogene, Serine/threonine kinase, V-Raf murine sarcoma viral oncogene homolog B, Serine/threonine-protein kinase B-Raf, Proto-oncogene B-Raf, BRAF1, RAFB1, B-raf proto-oncogene Serine/threonine-protein kinase, Murine sarcoma viral (V-Raf) oncogene homolog B1, B-raf serine/threonine-protein, 94 KDa B-raf protein, B-RAF1
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Entrez ID:
673
Related biomarkers:
Expression
Mutation
CNA
Fusion
Others
‹
KIAA1549-BRAF fusion (10)
BRAF fusion (9)
AGK-BRAF fusion (5)
SKAP2-BRAF fusion (4)
TARDBP-BRAF fusion (4)
FKBP15-BRAF fusion (3)
PPFIBP2-BRAF fusion (3)
CUL1-BRAF fusion (2)
SLC45A3-BRAF fusion (2)
SND1-BRAF fusion (2)
BRAF-MAD1L1 fusion (1)
BRAF-ZC3H7A fusion (1)
CUX1-BRAF fusion (1)
EXOC4-BRAF fusion (1)
NRF1-BRAF fusion (1)
TRIM33-BRAF fusion (1)
ZKSCAN1-BRAF fusion (1)
KIAA1549-BRAF fusion (10)
BRAF fusion (9)
AGK-BRAF fusion (5)
SKAP2-BRAF fusion (4)
TARDBP-BRAF fusion (4)
FKBP15-BRAF fusion (3)
PPFIBP2-BRAF fusion (3)
CUL1-BRAF fusion (2)
SLC45A3-BRAF fusion (2)
SND1-BRAF fusion (2)
BRAF-MAD1L1 fusion (1)
BRAF-ZC3H7A fusion (1)
CUX1-BRAF fusion (1)
EXOC4-BRAF fusion (1)
NRF1-BRAF fusion (1)
TRIM33-BRAF fusion (1)
ZKSCAN1-BRAF fusion (1)
›
Associations
(7)
News
Trials
Search handles
@StephenVLiu
Search handles
@StephenVLiu
Filter by
Latest
1year
Unique spectrum of BRAF alts in prostate cancer! 👉3% BRAF activated, mostly rearrangements and K601E. 👉Diverse BRAF fusions detected both in tissue DNA (F1CDx) and liquid ctDNA (F1LCDx). Love the teamwork here!🙌 @neerajaiims @montypal @EAntonarakis @HTukachinsky ()
1 year ago
Circulating tumor DNA
|
BRAF (B-raf proto-oncogene)
|
BRAF fusion • BRAF K601E • BRAF K601
|
FoundationOne® CDx • FoundationOne® Liquid CDx
over3years
#OncoAlert Case in #JCOPO @ASCO_pubs of #BRAF K601E NSCLC. No response to chemo/IO or 2L docetaxel but rapid response to trametinib. Unfortunately, fairly transient (4m). Need better options, more trials for BRAF non-V600E drivers. #LCSM https://t.co/HrAnmGpChI (@StephenVLiu)
over 3 years ago
Clinical
|
BRAF (B-raf proto-oncogene)
|
BRAF V600E • BRAF K601E • BRAF K601
|
Mekinist (trametinib) • docetaxel
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