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BIOMARKER:
BRAF G469V
i
Other names:
BRAF, B-raf proto-oncogene, B-raf proto-oncogene, Serine/threonine kinase, V-Raf murine sarcoma viral oncogene homolog B, Serine/threonine-protein kinase B-Raf, Proto-oncogene B-Raf, BRAF1, RAFB1, B-raf proto-oncogene Serine/threonine-protein kinase, Murine sarcoma viral (V-Raf) oncogene homolog B1, B-raf serine/threonine-protein, 94 KDa B-raf protein, B-RAF1
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Entrez ID:
673
Related biomarkers:
Expression
Mutation
CNA
Fusion
Others
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Associations
(7)
News
Trials
Search handles
@UmutDisel
@n8pennell
Search handles
@UmutDisel
@n8pennell
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Latest
almost2years
Has anyone tried an EGFR TKI in BRAF G469V mut? I have a pt whose tumor has this mut, came across this paper. #LCSM Lung Cancer Driven by BRAFG469V Mutation Is Targetable by EGFR Kinase Inhibitors https://t.co/lsyYRY65Cq (@n8pennell)
almost 2 years ago
EGFR (Epidermal growth factor receptor) • BRAF (B-raf proto-oncogene)
|
EGFR mutation • BRAF G469V
over3years
78Y M heavy smoker-Stage IV sarcomatoid NSCLC-PD-L1 %100- SD with weekly PaC-Carbo- TMB4-BRAF G469V-ClassII mutation. Started to Pembro-single agent.Any comment about-BRAF inh+MEK inh? @CharuAggarwalMD @StephenVLiu @VivekSubbiah @drgandara @christine_lovly @UmbertoMalapel1 (@UmutDisel)
over 3 years ago
PD(L)-1 Biomarker
|
PD-L1 (Programmed death ligand 1) • BRAF (B-raf proto-oncogene)
|
BRAF mutation • BRAF G469V
|
Keytruda (pembrolizumab)
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