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BIOMARKER:
BCR-ABL1 mutation
i
Other names:
BCR, BCR Activator Of RhoGEF And GTPase, BCR, RhoGEF And GTPase Activating Protein, Breakpoint Cluster Region Protein, Renal Carcinoma Antigen NY-REN-26, Breakpoint Cluster Region, D22S11, BCR1, BCR/FGFR1 Chimera Protein, FGFR1/BCR Chimera Protein, D22S662, ALL, CML, PHL, ABL proto-oncogene 1, ABL, c-ABL, JTK7, p150, ABL1
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Entrez ID:
25
;
613
Related biomarkers:
Expression
Mutation
CNA
Fusion
Others
‹
ABL1 T315I (5)
ABL1 E255K (2)
ABL1 G250E + ABL1 D276G + ABL1 T315I (2)
ABL1 D276G (1)
ABL1 F317L (1)
ABL1 F359V (1)
ABL1 G250E (1)
ABL1 L387M (1)
ABL1 M351T (1)
ABL1 T315I + ABL1 M351T + ABL1 L387M (1)
ABL1 Y253H (1)
BCR-ABL1 A337T (1)
BCR-ABL1 P465S (1)
BCR-ABL1 Q252H + BCR-ABL1 V299L (1)
BCR-ABL1 T315L (1)
BCR-ABL1 Y253H + BCR-ABL1 T315I (1)
ABL1 T315I (5)
ABL1 E255K (2)
ABL1 G250E + ABL1 D276G + ABL1 T315I (2)
ABL1 D276G (1)
ABL1 F317L (1)
ABL1 F359V (1)
ABL1 G250E (1)
ABL1 L387M (1)
ABL1 M351T (1)
ABL1 T315I + ABL1 M351T + ABL1 L387M (1)
ABL1 Y253H (1)
BCR-ABL1 A337T (1)
BCR-ABL1 P465S (1)
BCR-ABL1 Q252H + BCR-ABL1 V299L (1)
BCR-ABL1 T315L (1)
BCR-ABL1 Y253H + BCR-ABL1 T315I (1)
›
Associations
(3)
News
Trials
Search handles
@BldCancerDoc
@jvalentingg
Search handles
@BldCancerDoc
@jvalentingg
Filter by
Latest
over1year
Olverembatinib Benefit Holds Up in BCR-ABL1 T315I-Mutant, TKI-Resistant CML @ASH_hematology #mpnsm #ASH22 https://t.co/d4GwbtyWaV (@OncLive)
over 1 year ago
ABL1 (ABL proto-oncogene 1) • BCR (BCR Activator Of RhoGEF And GTPase)
|
BCR-ABL1 T315I • ABL1 T315I • BCR-ABL1 mutation
|
Nailike (olverembatinib)
2years
CML patients with high risk mutations do well with #BMT - disease control more important than presence of mutations The clinical significance of BCR-ABL1 mutations in patients with Ph+ chronic myeloid leukemia who underwent allo HCT @ASTCT_Journal #leusm https://t.co/maJgRSz9jg (@BldCancerDoc)
2 years ago
Clinical
|
ABL1 (ABL proto-oncogene 1) • BCR (BCR Activator Of RhoGEF And GTPase)
|
BCR-ABL1 mutation
over2years
Paper No: 307 #ASH21 Post Hoc Analysis of Responses to Ponatinib in Patients with Chronic-Phase Chronic Myeloid Leukemia By Baseline BCR-ABL1 Level and Baseline Mutation Status in the Optic Trial #CML @espGELMC (@jvalentingg)
over 2 years ago
Clinical • Retrospective data
|
ABL1 (ABL proto-oncogene 1) • BCR (BCR Activator Of RhoGEF And GTPase)
|
BCR-ABL1 mutation
|
Iclusig (ponatinib)
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