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BIOMARKER:
BCL2 mutation
i
Other names:
BCL2, Bcl-2, PPP1R50, B-cell CLL/lymphoma 2
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Entrez ID:
596
Related biomarkers:
Expression
Mutation
CNA
Fusion
Others
‹
MYC rearrangement + BCL2 rearrangement (22)
MYC rearrangement + BCL2 rearrangement + BCL6 rearrangement (6)
BCL2 G101V (4)
BCL2 rearrangement (3)
MYC translocation + BCL2 translocation (3)
BCL2 D103Y (2)
BCL2 F104I (1)
BCL2 G101V + SF3B1 mutation (1)
BCL2 N103E (1)
BCL2 N103Y (1)
BCL2 N107_N110dup (1)
BCL2 V156N (1)
EZH2 mutation + BCL2 translocation (1)
MYC translocation + BCL6 translocation + BCL2 translocation (1)
TP53 mutation + BCL2 rearrangement (1)
BCL2 translocation (0)
MYC rearrangement + BCL2 rearrangement+ BCL6 rearrangement (0)
MYC rearrangement + BCL2 rearrangement (22)
MYC rearrangement + BCL2 rearrangement + BCL6 rearrangement (6)
BCL2 G101V (4)
BCL2 rearrangement (3)
MYC translocation + BCL2 translocation (3)
BCL2 D103Y (2)
BCL2 F104I (1)
BCL2 G101V + SF3B1 mutation (1)
BCL2 N103E (1)
BCL2 N103Y (1)
BCL2 N107_N110dup (1)
BCL2 V156N (1)
EZH2 mutation + BCL2 translocation (1)
MYC translocation + BCL6 translocation + BCL2 translocation (1)
TP53 mutation + BCL2 rearrangement (1)
BCL2 translocation (0)
MYC rearrangement + BCL2 rearrangement+ BCL6 rearrangement (0)
›
Associations
(6)
News
Trials
Search handles
@MichaelDJain
Search handles
@MichaelDJain
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Latest
over2years
#ASH21 @BrianHill_MDPhD presents a multicentre exome seq of DLBCL biopsies prior to car t. Myc and BCL2 mutations associated with worse outcome. But interesting (to me) that KLHL6 was also bad, which we predicted causes resistance by tumor IFN signaling https://t.co/JSZu0OJYJd (@MichaelDJain)
over 2 years ago
Clinical • IO biomarker
|
BCL2 (B-cell CLL/lymphoma 2) • KLHL6 (Kelch Like Family Member 6)
|
BCL2 mutation
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