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BIOMARKER:
BAP1 mutation
i
Other names:
BAP1, BRCA1 Associated Protein 1, BRCA1 Associated Protein-1 (Ubiquitin Carboxy-Terminal Hydrolase), Ubiquitin Carboxyl-Terminal Hydrolase BAP1, Cerebral Protein 6, Ubiquitin Carboxy-Terminal Hydrolase, BRCA1-Associated Protein 1, Cerebral Protein-13, HUCEP-13, KIAA0272, Hucep-6, UCHL2
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Entrez ID:
8314
Related biomarkers:
Expression
Mutation
CNA
Others
‹
›
Associations
(14)
News
Trials
Search handles
@DrJNaidoo
@DrYukselUrun
@FunchainMD
@LindaMileshkin
@PauloBergerot
@StephenVLiu
@TiansterZhang
@drenriquegrande
Search handles
@DrJNaidoo
@DrYukselUrun
@FunchainMD
@LindaMileshkin
@PauloBergerot
@StephenVLiu
@TiansterZhang
@drenriquegrande
Filter by
Latest
1year
🔘 Exploration of Morphological Features of Clear Cell Renal Cell Carcinoma With PBRM1, SETD2, BAP1, or KDM5C Mutations #kidneycancer @IJSPjournal https://t.co/BfSG2ZNQU8 (@drenriquegrande)
1 year ago
PBRM1 (Polybromo 1) • BAP1 (BRCA1 Associated Protein 1) • SETD2 (SET Domain Containing 2, Histone Lysine Methyltransferase) • KDM5C (Lysine Demethylase 5C)
|
PBRM1 mutation • BAP1 mutation • KDM5C mutation
over1year
4-6% of our CUP cases were likely kidney cancer. May have NF2, FH and BAP1 mutations. Important to find these as they need immunotherapy or targeted therapy rather than chemotherapy (@LindaMileshkin)
over 1 year ago
Clinical • IO biomarker
|
BAP1 (BRCA1 Associated Protein 1)
|
BAP1 mutation
over1year
🚨 Our trial using a PARP+IO combination is still open to accrual to melanomas with any HRD mutation including any metastatic uveal melanoma with a BAP1 (or other HRD) mutation #SMR2022 🚨 https://t.co/2m5qbHaKks @ta_sussman @BrianGastmanMD (@FunchainMD)
over 1 year ago
HRD (Homologous Recombination Deficiency) • BAP1 (BRCA1 Associated Protein 1) • PARP1 (Poly(ADP-Ribose) Polymerase 1)
|
BAP1 mutation
almost2years
Could there finally be a drug to slow and stop mesotheliomas from growing and spreading? Encouraging research led by @MGZauderer shows promise for patients containing a BAP1 mutation.https://t.co/x9GIATwjMw (@MSKCancerCenter)
almost 2 years ago
Clinical
|
BAP1 (BRCA1 Associated Protein 1)
|
BAP1 mutation
2years
Clinical presentation, diagnostic & treatment challenges, & expert recommendations of the best care for patients with #mesothelioma who carry inactivating germline BAP1 mutations: https://t.co/NJnTv8CWBW @JTOonline @MCarboneMD @theNCI #LCSM (@DrJNaidoo)
2 years ago
Clinical
|
BAP1 (BRCA1 Associated Protein 1)
|
BAP1 mutation
over2years
Report in #JTOCRR @JTOonline: Phase II study of olaparib 300mg bid in mesothelioma. Promising rationale but limited efficacy: RR 4%, PFS 3.6m, OS 8.7m. Worse outcomes associated with #BAP1 germline mutations. #MPM @OncoAlert @IASLC https://t.co/fCpX7MfNNn (@StephenVLiu)
over 2 years ago
Clinical
|
BAP1 (BRCA1 Associated Protein 1)
|
BAP1 mutation
|
Lynparza (olaparib)
almost3years
Melanoma vs bap1 mutated neoplasm vs spitz vs reticulohistiocytoma vs some other histiocytosis (@et565)
almost 3 years ago
BAP1 (BRCA1 Associated Protein 1)
|
BAP1 mutation
3years
Discovery of BAP1 mutated aggressive #kidneycancers from @JBrugarolas lab. Loving this March series from @KimrynRathmell @brian_rini of key papers for #RCCawareness month!! (@TiansterZhang)
3 years ago
BAP1 (BRCA1 Associated Protein 1)
|
BAP1 mutation
3years
Congratulations former Brugarolas Lab trainee @Sam_PenaLlopis @DKTK_ on recent paper highlighting pathological potential of synonymous BAP1 mutations in kidney cancer. @JBrugarolas discusses findings in @TheScientistLLC https://t.co/d58RZtP2hX @UTSWNews https://t.co/QZlhAJBGlo (@KCPUTSW)
3 years ago
BAP1 (BRCA1 Associated Protein 1)
|
BAP1 mutation
3years
▶️ Radiomic features of RCC primary & metastatic sites as predictors of TERT & BAP1 mutations: a non-invasive method of discerning mutational status in pts w mRCC @LuisMezaco @arafflemd @NazliDizman @ammar_rad @montypal @CityofHopeCME #GU21 @ASCO 👉 https://t.co/mhN3XBKo36 (@PauloBergerot)
3 years ago
Clinical
|
TERT (Telomerase Reverse Transcriptase) • BAP1 (BRCA1 Associated Protein 1)
|
BAP1 mutation
over3years
Smells like high grade clear cell RCC Also consider BAP1 mutated RCC (novel; see below) (@slusagar)
over 3 years ago
BAP1 (BRCA1 Associated Protein 1)
|
BAP1 mutation
over3years
Biological Mechanisms and Clinical Significance of BAP1 Mutations in Human Cancer! @CD_AACR #michelecarbone @UHCancerCenter @JBrugarolas @MDAndersonNews @CancerAlliance @KidneyCancer @OncoAlert https://t.co/3oDR9v6Kvy (@DrYukselUrun)
over 3 years ago
Clinical
|
BAP1 (BRCA1 Associated Protein 1)
|
BAP1 mutation
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