^
    Contact us  to learn more about
    our Premium Content:  News alerts, weekly reports and conference planners
    BIOMARKER:

    ALK V1180L

    i
    Other names: NBLST3, CD246, Anaplastic Lymphoma Kinase, Anaplastic Lymphoma Kinase (Ki-1), CD246 Antigen, Mutant Anaplastic Lymphoma Kinase, ALK, ALK Receptor Tyrosine Kinase, Anaplastic Lymphoma Receptor Tyrosine Kinase, ALK Tyrosine Kinase Receptor
    Entrez ID:
    238
    Related biomarkers:
    Expression
    Mutation
    CNA
    Fusion
    Others
    almost2years
    @DrHendifar @PancPathologist have had success w/ #ALK fusion in metastatic #PDAC following #FOLFIRINOX responsive to #alectinib then acquired alectinib-resistant ALK mutations G1202R and V1180L on G360, then w/benefit to 3rd-gen ALK inh #lorlatinib https://t.co/JnI2dntOfv #pancsm ()
    ALK (Anaplastic lymphoma kinase)
    |
    ALK fusion • ALK mutation • ALK G1202R • ALK V1180L
    |
    Guardant360® CDx
    |
    5-fluorouracil • Alecensa (alectinib) • Lorbrena (lorlatinib) • leucovorin calcium