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BIOMARKER:
ALK I1171S
i
Other names:
NBLST3, CD246, Anaplastic Lymphoma Kinase, Anaplastic Lymphoma Kinase (Ki-1), CD246 Antigen, Mutant Anaplastic Lymphoma Kinase, ALK, ALK Receptor Tyrosine Kinase, Anaplastic Lymphoma Receptor Tyrosine Kinase, ALK Tyrosine Kinase Receptor
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Entrez ID:
238
Related biomarkers:
Expression
Mutation
CNA
Fusion
Others
‹
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Associations
(2)
News
Trials
Search handles
@StephenVLiu
Search handles
@StephenVLiu
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almost4years
#ASCO20 Response to brigatinib (post-alectinib) noted in the presence of various #ALK resistance mutations including G1202R (1/3), L1196M (3/3), I1171N (1/2), I1171S (1/1). Well tolerated. Most common G3 tox were lipase (no pancreatitis), CK (no myalgias), HTN. #OncoAlert #LCSM (@StephenVLiu)
almost 4 years ago
ALK (Anaplastic lymphoma kinase)
|
ALK mutation • ALK G1202R • ALK I1171N • ALK I1171 • ALK L1196M • ALK I1171S • ALK L1196M + ALK G1202R
|
Alecensa (alectinib) • Alunbrig (brigatinib)
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