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BIOMARKER:
ABL2 fusion
i
Other names:
ABL2, ABL Proto-Oncogene 2, Non-Receptor Tyrosine Kinase, V-Abl Abelson Murine Leukemia Viral Oncogene Homolog 2, C-Abl Oncogene 2, Non-Receptor Tyrosine Kinase, Abelson Tyrosine-Protein Kinase 2, Abelson-Related Gene Protein, Tyrosine-Protein Kinase ABL2, Tyrosine-Protein Kinase ARG, ABLL, ARG, V-Abl Abelson Murine Leukemia Viral Oncogene Homolog 2 (Arg, Abelson-Related Gene), Abelson Murine Leukemia Viral Oncogene Homolog 2, Abelson-Related Gene, Lnc-ANGPTL1-6
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Entrez ID:
27
Related biomarkers:
Fusion
‹
›
Associations
(2)
News
Trials
Search handles
@FadiHaddad_MD
@NitinJainMD
Search handles
@FadiHaddad_MD
@NitinJainMD
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Latest
9ms
Summary on the management of Ph-like #ALL ➡️ TKIs effective in patients with ABL1 or ABL2 fusions, mostly in the first-line setting ➡️ ANTIBODIES (InO, blina) improve outcomes ➡️ Favor transplant in CR1 #leusm @NitinJainMD @jayastuMD @_MDEducation (@FadiHaddad_MD)
9 months ago
Clinical
|
ABL1 (ABL proto-oncogene 1) • ABL2 (ABL Proto-Oncogene 2, Non-Receptor Tyrosine Kinase)
|
ABL2 fusion
over2years
Here is a summary of ABL1 and ABL2 fusions seen in Ph-Like ALL. Important to know these translocations as conventional cytogenetics may give a clue | Preclinical and anecdotal clinical data to support TKI use #leusm @MDAndersonNews (@NitinJainMD)
over 2 years ago
Clinical data
|
ABL1 (ABL proto-oncogene 1) • ABL2 (ABL Proto-Oncogene 2, Non-Receptor Tyrosine Kinase)
|
ABL2 fusion
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