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    BIOMARKER:

    FGFR2-SORBS1 fusion

    i
    Other names: SORBS1, Sorbin And SH3 Domain Containing, Ponsin, Sorbin And SH3 Domain-Containing Protein 1, C-Cbl-Associated Protein, SH3 Domain Protein 5, SH3P12, SH3D5, Fas-Ligand Associated Factor 2, SH3-Domain Protein 5 (Ponsin), C-Cbl Associated Protein, FLJ12406, Sh3p12, FLAF2, R85FL 1, FGFR2, BEK, CD332, CEK3, CFD1, ECT1, JWS, K-SAM, KGFR, TK14, TK25, Fibroblast growth factor receptor 2
    Entrez ID:
    2263; 10580
    Related biomarkers:
    Expression
    Mutation
    CNA
    Fusion
    Others
    Associations
    News
    Trials
    over2years
    Genomic Profiling of Pancreatic Ductal Adenocarcinoma, Intrahepatic and Extrahepatic Cholangiocarcinoma (USCAP 2022)
    "Our data show that the presence of IDH1, BAP1 mutation and FGFR2 fusion supports the diagnosis of iCCA. Tumors with loss of CDKN2A/B and/or SMAD4 and ATM mutations were most likely PDC. Our results support the previous molecular findings in CCA and PDC."
    KRAS (KRAS proto-oncogene GTPase) • TP53 (Tumor protein P53) • FGFR2 (Fibroblast growth factor receptor 2) • IDH1 (Isocitrate dehydrogenase (NADP(+)) 1) • IDH2 (Isocitrate Dehydrogenase (NADP(+)) 2) • ATM (ATM serine/threonine kinase) • CDKN2A (Cyclin Dependent Kinase Inhibitor 2A) • BAP1 (BRCA1 Associated Protein 1) • SMAD4 (SMAD family member 4) • CDKN2B (Cyclin Dependent Kinase Inhibitor 2B) • BICC1 (BicC Family RNA Binding Protein 1) • SORBS1 (Sorbin And SH3 Domain Containing 1)
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    TP53 mutation • KRAS mutation • KRAS G12C • IDH1 mutation • ATM mutation • FGFR2 mutation • FGFR2 fusion • KRAS G12R • FGFR fusion • BAP1 mutation • KRAS G12 • KRAS Q61H • TP53 mutation + KRAS mutation • FGFR2-SORBS1 fusion • BAP1 mutation + FGFR2 fusion
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    Archer® FusionPlex® Comprehensive Thyroid & Lung (CTL) Kit