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Show legend
Group by Gene:
Include preclinical:

pembrolizumab
nivolumab
toripalimab
PF-06801591
0
PD1 inhibitor
tislelizumab
AB122
dostarlimab
INCMGA0012
PD1 inhibitor
olaparib
1
PARP inhibitor
rucaparib
niraparib
PARP inhibitor
atezolizumab
2
PD-L1 inhibitor
durvalumab
avelumab
PD-L1 inhibitor
bevacizumab
Mvasi (bevacizumab biosimilar)
3
VEGF-A inhibitor
Bevax (bevacizumab biosimilar)
Zirabev (bevacizumab biosimilar)
Aybintio (bevacizumab biosimilar)
Krabeva (bevacizumab biosimilar)
cisplatin
4
DNA synthesis inhibitor
gemcitabine
cisplatin + gemcitabine
mitomycin urothelial gel
pazopanib
5
Multi-tyrosine kinase inhibitor
cabozantinib tablet
cabozantinib capsule
ponatinib
everolimus
6
mTOR inhibitor
temsirolimus
sirolimus
mTOR inhibitor
triptorelin
7
GnRH agonist
histrelin acetate
goserelin acetate
darolutamide
apalutamide
8
Androgen receptor antagonist
bicalutamide
EPI-7386
BMS-641988
infigratinib
BAY1163877
ABSK-091
9
FGFR inhibitor
pemigatinib
Debio 1347
ARQ 087
AZ8010
FGFR inhibitor
10
PD1 inhibitor, CTLA4 inhibitor
nivolumab + ipilimumab
abiraterone acetate
11
CYP17A1 inhibitor
AST-2970
abiraterone acetate
CYP17A1 inhibitor
carboplatin + gemcitabine
12
Tubulin polymerization promoter, DNA synthesis inhibitor
paclitaxel + gemcitabine
cisplatin + paclitaxel
abiraterone acetate + triptorelin
13
CYP17A1 inhibitor, GnRH agonist
abiraterone acetate + histrelin acetate
abiraterone acetate + goserelin acetate
14
GnRH antagonist
relugolix
degarelix
15
IFNα stimulant, VEGF-A inhibitor
bevacizumab + pegylated interferon α -2a
Aybintio (bevacizumab biosimilar) + pegylated interferon α -2a
leuprolide mesylate injectable suspension
16
GnRH stimulant
leuprolide acetate
GnRH stimulant
mitoxantrone
17
Topoisomerase II inhibitor
etoposide IV
doxorubicin hydrochloride
capecitabine
18
Thymidylate synthase inhibitor
5-fluorouracil
5-fluorouracil
histrelin acetate + nilutamide
bicalutamide + goserelin acetate
19
Androgen receptor antagonist, GnRH agonist
goserelin acetate + nilutamide
bicalutamide + triptorelin
triptorelin + nilutamide
bicalutamide + histrelin acetate
enzalutamide
20
Androgen receptor inhibitor
enzalutamide + EPI-7170
SID 3712502
21
VEGFR inhibitor, PD1 inhibitor
pembrolizumab + axitinib
22
c-MET inhibitor
savolitinib
c-MET inhibitor
23
PD1 inhibitor, Multi-tyrosine kinase inhibitor
nivolumab + cabozantinib tablet
24
Immunostimulant
sipuleucel-T
RV001
25
VEGF-A inhibitor, EGFR inhibitor
bevacizumab + erlotinib
26
Tubulin polymerization promoter
paclitaxel
carboplatin
27
Microtubule inhibitor
cabazitaxel
28
VEGFR inhibitor, PD-L1 inhibitor
avelumab + axitinib
leuprolide acetate + bicalutamide
29
GnRH stimulant, Androgen receptor antagonist
leuprolide acetate + nilutamide
leuprolide acetate + apalutamide
30
VEGFR inhibitor
axitinib
31
EGFR inhibitor
erlotinib
cetuximab
32
GnRH stimulant, Androgen receptor inhibitor
leuprolide acetate + flutamide
33
Topoisomerase II inhibitor, DNA inhibitor, DNA synthesis inhibitor
cisplatin + etoposide oral
34
Tubulin polymerization promoter, Microtubule inhibitor
carboplatin + cabazitaxel
35
Bone resorption factor inhibitor, Osteoclast inhibitor
zoledronic acid
36
PI3K inhibitor, AKT inhibitor
GDC-0068
37
CXCL12 inhibitor, Farnesyl transferase inhibitor
tipifarnib
38
FGFR inhibitor, PD-L1 inhibitor
atezolizumab + BAY1163877
durvalumab + ABSK-091
39
PD1 inhibitor, PI3Kγ inhibitor
nivolumab + IPI-549
40
HIF-2α inhibitor
belzutifan
PT2385
41
CTLA4 inhibitor
ipilimumab
42
Ionizing radiation emitter, PSMA inhibitor
177 Lu PSMA-617
43
ALK inhibitor
crizotinib
alectinib
44
IL-15R agonist
inbakicept
45
PARP inhibitor, AKT inhibitor
olaparib + AZD5363
46
PLK1 inhibitor
PCM-075
47
Androgen receptor inhibitor, mTOR inhibitor, DNA PK inhibitor
enzalutamide + CC-115
48
FGFR3 inhibitor
B-701
FGFR3 inhibitor
49
FGFR antagonist
TAS 120
50
HER2 inhibitor, HER2 dimerization inhibitor
trastuzumab + pertuzumab
51
PD1 inhibitor, IDO1 inhibitor
nivolumab + BMS-986205
pembrolizumab + INCB024360
52
ALK inhibitor, Multi-tyrosine kinase inhibitor
crizotinib + pazopanib
53
HDAC inhibitor, Multi-tyrosine kinase inhibitor
pazopanib + CG-781
54
mTORC1 inhibitor, mTORC2 inhibitor
TAK-228
55
PI3K inhibitor
BKM120
MEN1611
56
RORγ inverse agonist
XY123
57
VEGF-A inhibitor, PI3Kγ inhibitor, Tubulin inhibitor
bevacizumab + albumin-bound paclitaxel + IPI-549
58
BRAF inhibitor
vemurafenib
59
VEGFR-2 inhibitor, c-MET inhibitor
GSK1363089
60
PD1 inhibitor, EphB4 inhibitor
pembrolizumab + sEphB4-HSA
61
MEK inhibitor
trametinib
62
PD1 inhibitor, ICOS agonist
pembrolizumab + GSK3359609
63
CDC7 kinase inhibitor
LY3143921
64
HER2 inhibitor
trastuzumab
65
VEGFR inhibitor, mTOR inhibitor
temsirolimus + axitinib
66
CYP17A1 inhibitor, PARP inhibitor
olaparib + abiraterone acetate
67
PI3Kβ inhibitor
GSK2636771
68
VEGFR inhibitor, PDGFR inhibitor, c-KIT inhibitor
sunitinib
69
FGFR inhibitor, VEGFR inhibitor, RET inhibitor, c-KIT inhibitor, PDGFR α antagonist
lenvatinib
70
Microtubule stabilizer, Tubulin polymerization promoter
docetaxel
carboplatin + docetaxel
71
FGFR2 inhibitor, FGFR inhibitor, FGFR1 inhibitor, FGFR3 inhibitor, FGFR4 inhibitor
erdafitinib
72
VEGFR-2 inhibitor, RAF kinase inhibitor, BRAF inhibitor, PDGFR β antagonist
sorafenib
73
FGFR inhibitor, VEGFR inhibitor, RET inhibitor, PD1 inhibitor, c-KIT inhibitor, PDGFR α antagonist
pembrolizumab + lenvatinib
74
Nectin-4-targeted antibody-drug conjugate, Microtubule inhibitor
enfortumab vedotin
75
Trop-2-targeted antibody-drug conjugate, Topoisomerase I inhibitor
sacituzumab govitecan-hziy
goserelin acetate + flutamide
76
Androgen receptor inhibitor, GnRH agonist
triptorelin + flutamide
histrelin acetate + flutamide
77
Bifunctional alkylating agent, Topoisomerase II inhibitor, DNA synthesis inhibitor
gemcitabine + ifosfamide + pegylated liposomal doxorubicin
cisplatin + doxorubicin hydrochloride + ifosfamide + etoposide IV
78
GnRH stimulant, CYP17A1 inhibitor
abiraterone acetate + leuprolide acetate
79
DNA synthesis inhibitor, Thymidylate synthase inhibitor
cisplatin + 5-fluorouracil
80
VEGFR-3 antagonist, VEGFR-2 inhibitor, VEGFR-1 antagonist
tivozanib
81
FGFR inhibitor, VEGFR inhibitor, RET inhibitor, mTOR inhibitor, c-KIT inhibitor, PDGFR α antagonist
everolimus + lenvatinib
82
Microtubule stabilizer, Tubulin polymerization promoter, Steroid receptor agonist
docetaxel + prednisone
83
Topoisomerase II inhibitor, Tubulin polymerization promoter, DNA inhibitor
carboplatin + etoposide oral
84
Topoisomerase II inhibitor, Tubulin polymerization promoter
carboplatin + etoposide IV
85
CD122 agonist, IL-2 stimulant
aldesleukin
86
GnRH antagonist, CYP17A1 inhibitor
abiraterone acetate + degarelix
87
HER2 inhibitor, HER4 inhibitor, EGFR inhibitor
afatinib
88
PARP2 inhibitor, PARP inhibitor
talazoparib
89
PD-L1 inhibitor, CTLA4 inhibitor
durvalumab + CP-675206
90
PD-L1 inhibitor, VEGF-A inhibitor
bevacizumab + atezolizumab
91
GCR agonist, CYP17A1 inhibitor, PI3K inhibitor, AKT inhibitor
GDC-0068 + AST-2970 + prednisolone
92
PD-L1 inhibitor, PD1 inhibitor
durvalumab + MEDI0680
93
Tubulin polymerization promoter, PARP inhibitor
PARP inhibitor + carboplatin
94
PD1 inhibitor, Androgen receptor inhibitor
pembrolizumab + enzalutamide
95
HER2-targeted antibody-drug conjugate, Microtubule inhibitor
disitamab vedotin
96
PD1 inhibitor, HER2-targeted antibody-drug conjugate, Microtubule inhibitor
toripalimab + disitamab vedotin
97
FGFR2 inhibitor, FGFR inhibitor, FGFR1 inhibitor, FGFR3 inhibitor, PD1 inhibitor, FGFR4 inhibitor
erdafitinib + JNJ-63723283
98
GnRH antagonist, CYP17A1 inhibitor, Androgen receptor antagonist
abiraterone acetate + degarelix + bicalutamide implant
99
TIM-1-targeted antibody-drug conjugate, Microtubule inhibitor
CDX-014
100
PD-L1 inhibitor, VEGF-A inhibitor, PI3Kγ inhibitor
bevacizumab + atezolizumab + IPI-549
101
Alkylating agent, GCR agonist, Immunomodulator
cyclophosphamide oral + dexamethasone
102
Topoisomerase II inhibitor, DNA synthesis inhibitor
etoposide IV + bleomycin
103
Ionizing radiation emitter, Androgen receptor inhibitor, PSMA inhibitor
enzalutamide + 177 Lu PSMA-617
104
PLK1 inhibitor, CYP17A1 inhibitor, Steroid receptor agonist
prednisone + AST-2970 + PCM-075
105
CDK4 inhibitor, CDK6 inhibitor
palbociclib
abemaciclib
106
Topoisomerase II inhibitor, Microtubule stabilizer, Tubulin polymerization promoter
paclitaxel + docetaxel + etoposide IV
107
PD-L1 inhibitor, mTOR inhibitor, mTORC2 inhibitor
durvalumab + AZD2014
108
CD137 agonist, HER2 inhibitor
PRS-343
109
STAT3 inhibitor, PD1 inhibitor
pembrolizumab + BBI608
110
STEAP1-targeted antibody-drug conjugate, Microtubule inhibitor
RG7450
111
Ionizing radiation emitter, PD1 inhibitor, PSMA inhibitor
pembrolizumab + 177 Lu PSMA-617
112
B7-H3-targeted antibody-drug conjugate, Topoisomerase I inhibitor
DS-7300
113
OGT inhibitor
OSMI-1
114
MCL1 inhibitor, XIAP antagonist, MDMX inhibitor, ABCG2 inhibitor, Survivin inhibitor
FL118
115
FGFR inhibitor, VEGFR inhibitor, PDGFR inhibitor, pan-TRK inhibitor
TKI258
116
Tyrosine kinase inhibitor
PD 0173074
Tyrosine kinase inhibitor
117
PPAR γ agonist
rosiglitazone
118
Ferroptosis inducer
RSL3
erastin
119
Glutathione peroxidase 4 inhibitor, Ferroptosis inducer
ML210
120
VEGFR inhibitor, PDGFR inhibitor, Multi-tyrosine kinase inhibitor, c-KIT inhibitor
sunitinib + pazopanib
121
PIK3C3 inhibitor, FGFR inhibitor
MPT0L145
122
RAC1 inhibitor
NSC23766
123
C4.4a-targeted antibody-drug conjugate, Microtubule inhibitor
BAY1129980
124
MAT2A inhibitor
IDE397
125
EZH2 inhibitor
CPI-0209
GSK2816126
126
Bcr-abl tyrosine kinase inhibitor
INNO-406
127
AKT inhibitor
MK-2206
128
p53 reactivator
APR-246
129
VEGFR inhibitor, PDGFR inhibitor, VEGFR-2 inhibitor, RAF kinase inhibitor, BRAF inhibitor, c-KIT inhibitor, PDGFR β antagonist
sorafenib + sunitinib
130
WEE1 inhibitor
AZD1775
131
WDR5 inhibitor
OICR-9429
132
FGFR inhibitor, Bcr-abl tyrosine kinase inhibitor, Src kinase inhibitor, c-KIT inhibitor, PDGFR β antagonist, EphA2 receptor antagonist
dasatinib + infigratinib
133
Alkylating agent
LP-184
134
VEGFR-2 inhibitor, RAF kinase inhibitor, Hyaluronic acid synthase inhibitor, BRAF inhibitor, PDGFR β antagonist
sorafenib + 4-methylumbelliferone
135
α1 adrenergic receptor antagonist
silodosin
136
PDE5 inhibitor
sildenafil
137
Microtubule stabilizer, Tubulin polymerization promoter, Microtubule inhibitor
docetaxel + cabazitaxel
138
CD3 agonist, PSMA inhibitor
JNJ-63898081
139
Chk1 inhibitor
LY2606368
140
PSMA-targeted CAR-T immunotherapy
AUTO7
141
HER2 inhibitor, EGFR inhibitor
lapatinib
142
CD3 agonist, STEAP1 inhibitor
AMG 509
143
GnRH stimulant, CYP17A1 inhibitor, Androgen receptor antagonist
AST-2970 + bicalutamide implant + leuprorelin depot
144
ERK inhibitor, Androgen receptor antagonist, AKT inhibitor
darolutamide + ONC201
145
DNA synthesis inhibitor, Cytidine deaminase inhibitor, DNA methylation inhibitor
gemcitabine + EPI01
146
Adenosine A2A receptor antagonist, Androgen receptor antagonist
apalutamide + AZD4635
147
Adenosine A2A receptor antagonist
AZD4635
148
Bcr-abl tyrosine kinase inhibitor, mTOR inhibitor, Src kinase inhibitor, c-KIT inhibitor, PDGFR β antagonist, EphA2 receptor antagonist
dasatinib + AZD8055
149
B7-H3-targeted antibody-drug conjugate, DNA replication inhibitor
MGC018
150
CDK7 inhibitor
YPN005
SY‑079
151
DOT1L inhibitor
EPZ-5676
EPZ004777
152
SLC44A4-targeted antibody-drug conjugate, Microtubule inhibitor
ASG 5ME
153
DNA methylation inhibitor
TdCyd
154
Steroid receptor agonist
prednisone
155
PD1 inhibitor, PARP inhibitor
pembrolizumab + olaparib
156
MAPK inhibitor, p38 inhibitor
SB202190
157
MEK2 inhibitor, MEK1 inhibitor
U0126
158
BTK inhibitor
ibrutinib
159
PRC2 inhibitor
MRTX2219
160
CYP17A1 inhibitor, PI3K inhibitor, AKT inhibitor
abiraterone acetate + GDC-0068
161
Androgen receptor inhibitor, AKT inhibitor
enzalutamide + AZD5363
162
AKT2 inhibitor, AKT1 inhibitor
BAY 1125976
163
Androgen receptor antagonist, TMPRSS2 inhibitor
GT0918
164
CYP17A1 inhibitor, Androgen receptor inhibitor
enzalutamide + abiraterone acetate
enzalutamide + abiraterone acetate
165
Immunotherapy
Immunotherapy
166
VEGF inhibitor
VEGF inhibitor
167
Src kinase inhibitor, PARP inhibitor
PARP inhibitor + Src kinase inhibitor
168
ATM kinase inhibitor
ATM kinase inhibitor
169
FGFR2 inhibitor
FGFR2 inhibitor
170
mTORC1 inhibitor
mTORC1 inhibitor
171
Chemotherapy
EP
172
Glutamate inhibitor
Glutamate inhibitor
No biomarker
PD-L1 expression
TMB-H + PD-L1 expression
PD-L1 overexpression
PD-L1 negative
PD-L1-H
DDR + PD-L1 expression
PD-L1 underexpression
PD-L1 expression + T-cell gene signature
FGFR3 mutation
FGFR3 fusion
FGFR3 A393E
FGFR3 S249C
FGFR3 expression
FGFR3 Y373C
FGFR3 overexpression
FGFR3 Y375C
FGFR3 R248C
FGFR3 G380R
FGFR3 G370C
FGFR3 V443L
FGFR3 L496V
FGFR3 V443M
MET amplification
PTEN deletion
MET mutation
PTEN mutation
PTEN loss
PTEN negative
MET fusion
PTEN expression
PTEN N323fs*21
BRCA2 mutation
BRCA2 deletion
BRCA2 positive
BRCA2 L557*
BRCA2 biallelic inactivation
BRCA2 A902fs*2
BRCA2 amplification
BRCA2 exon 11 deletion
BRCA2 underexpression
RAD54L mutation
FANCL mutation
BRCA1 mutation
BRCA1 positive
ERCC2 N238S
ERCC2 E606Q
BRCA1 deletion
ERCC2 Y24C
ERCC2 D609E
ERCC2 D609G
ERCC2 G665A
BRCA1 N1018fs*8
ERCC2 E606G
BRCA1 biallelic inactivation
ERCC2 P463L
ERCC2 V242F
BRCA1 underexpression
HER-2 amplification
HER-2 positive
HER-2 overexpression
HER-2 expression
HER-2 mutation
MTOR mutation
ATM positive
ATM mutation
MTOR E2419K
HRAS Q61R
HRAS H27_28fs*
HRAS G12S
ATM deletion
HRAS G12C
HRAS mutation
MTOR Q2223K
MTOR E2014K
HRAS G13R
ATM underexpression
ATM biallelic inactivation
MSI-H/dMMR
KDR rs2071559
FGFR mutation
FGFR overexpression
AR overexpression
AR positive
AR mutation
KDR expression
FGFR fusion
AR T878A
AR elevation
KDR C482R
FGFR expression
AR T877A
AR L702H
AR splice variant 7 expression
AR F877L
AR expression
AR splice variant 9
AR amplification
AR W741C
AR W741L
AR F877L + AR T878A
AR F876L
AR splice variant 7
TMB-H
FLT1 rs9554320
PBRM1 mutation
TSC1 mutation
PBRM1 overexpression
FGFR1 mutation
FGFR1 amplification
ERBB3 mutation
FGFR1 expression
PBRM1 deletion
FGFR1 overexpression
PBRM1 negative
TSC1 deletion
TSC1 1907_1908del
FLT1 expression
TSC1 deletion
ERBB3 G284R
ERBB3 V104M
ERBB3 R103G
PBRM1 underexpression
ERBB3 expression
ARID1A mutation
AXL-L
ROBO3 mutation
PD-1 expression
FGFR3-TACC3 fusion
PD-1 overexpression
FGFR3-TACC3 F17T8
BAP1 I696T
BAP1 mutation
FGFR2 fusion
FGFR2 mutation
FGFR2 A391E
BAP1 negative
FGFR2 underexpression
AXL expression
PD-1-H
BAP1 deletion
FGFR3-TACC3 fusion
AXL overexpression
RB1 mutation
VHL mutation
ALK rearrangement
MSH2 deletion
MLH1 deletion
CDK12 mutation
MSH2 mutation + MSH6 mutation
FANCA deletion
FANCA mutation
FOLH1 expression
PALB2 mutation
PIK3CA M1043I
MLH1 mutation
TSC2 H1620R + TSC2 Y1650C
TSC2 mutation
HMOX1-L
IFNG expression
HGF-L
PALB2 deletion
HGF expression
HMOX1 expression
CDK12 deletion
CYP17A1 V366M
PIK3CA mutation
HDAC2 mutation
IFNG RNA sig
MSH2 negative + MSH6 negative
FOLH1 positive
CYP17A1 expression
HDAC2 expression
VHL promoter methylation
RB1 expression
HGF-H
RB1 deletion
PIK3CA mutation + MSI-L/dMMR
FGF mutation
LRP1B mutation
STEAP1 expression
ATRX mutation
RAD50 mutation
WRN mutation
CPM elevation
FANCG mutation
FANCI mutation
FANCM mutation
TUBB3 overexpression
Apolipoprotein B elevation
TP53 mutation
HRD
CA9 expression
CD31 expression
GNAQ mutation
IKZF2-L
KDM5C mutation
YBX1 rs10493112
PDGFRA expression
CD8 expression
CXCL10 overexpression
CEACAM1 overexpression
PD-L2 overexpression
BRIP1 mutation
HIF1A expression
CYB5A rs1790834
ELTD1 expression
FGFR2-CASP7 fusion
IFNA1 expression
FGFR2-BICC1 fusion
TGFB1 underexpression
FGF10 amplification
CDKN2A mutation
IL6R L
IL6-L
IL6ST-H
BRCA2 mutation + TP53 mutation
BRCA1 mutation + TP53 mutation
BRCA2 deletion + ATM mutation
TERT promoter mutation
CDKN2B mutation
TFEB translocation
SYNE1 mutation
CXCL13 mutation + ARID1A mutation
SPOP mutation + CHD1 deletion
CHD1 deletion
SPOP mutation
PCSK9 underexpression
LRP1B mutation + TMB-H
CXCL13 expression
IL18BP expression
CXCL9 expression
VEGFA expression
CSF1 expression
TIMP1 expression
EWSR1-POU5F1 fusion
ANGPT2 expression
RNF43 mutation
IL18 expression
RB1 mutation + PD-L1 expression
KMT2C mutation
CXCL8-L
SPP1-L
TLR4-L
LDH elevation
BRAF mutation
SNAI2 deletion
CTLA4 promoter hypomethylation
NANOGNB mutation
HAVCR2 expression
ERVE-4 expression
CD276 overexpression
EPHB2 expression
FH mutation
PBRM1 mutation + SETD2 mutation
MSI-H + MSH2 expression + MSH6 expression
ARID2 H1495fs*8
SMARCB1 deletion
RB1 mutation + TP53 mutation
BIRC5 expression
NRF1-BRAF fusion
MSH6 deletion
FGFR3-BAIAP2L1 fusion
MSH4 L359I
AFP elevation
MSI-H/dMMR + TMB-H
miR138 underexpression + miR497 overexpression
TET1 mutation
HRD + BRCA2 mutation
PMS2 mutation + MLH1 mutation
MSH2 mutation + MSH6 mutation + BRCA1 mutation
NF2 mutation
PD-L1 expression + TMB-H
NECTIN4 expression
TFE3 translocation
FANCF mutation
FLCN mutation
KIM1 expression
BARD1 mutation
RAD51D mutation
RAD51C mutation
RAD51B mutation
CHEK1 mutation
CHEK2 mutation
TP53 expression
KIM1 elevation
VEGFA-H
CXCL13 elevation
CD276 expression
IL6 elevation
IL6-H
FLCN deletion
TERT overexpression
CXCL10-H
CXCL8 elevation