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BIOMARKER:
U2AF1 mutation
i
Other names:
U2AF1, U2 Small Nuclear RNA Auxiliary Factor 1, U2(RNU2) Small Nuclear RNA Auxiliary Factor Binding Protein, U2 SnRNP Auxiliary Factor Small Subunit, Splicing Factor U2AF 35 KDa Subunit, U2AFBP, U2AF35, U2 Small Nuclear Ribonucleoprotein Auxillary Factor, 35-KD Subunit, U2(RNU2) Small Nuclear RNA Auxiliary Factor 1, U2 Small Nuclear RNA Auxillary Factor 1, Splicing Factor U2AF 35kDa Subunit, U2 Auxiliary Factor 35 KDa Subunit, RNU2AF1, FP793, RN
Associations
(8)
News
Trials
C2 | Sensitive
C3 | Sensitive
D | Sensitive
C2 | Resistant
C3 | Resistant
D | Resistant
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Include preclinical:
Drug categories
Tyrosine Kinase Inhibitors
Kinase Inhibitors
Chemotherapy
DNA
Other
Epigenetics
BCL Inhibitors
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Acute Myelogenous Leukemia
Myelodysplastic Syndrome
CA-4948
C2
U2AF1 mutation
|
Acute Myelogenous Leukemia
|
CA-4948
C2
U2AF1 mutation
|
Myelodysplastic Syndrome
|
CA-4948
venetoclax + ABBV 075
C3
U2AF1 mutation
|
Acute Myelogenous Leukemia
|
venetoclax + ABBV 075
azacitidine
C3
U2AF1 mutation
|
Myelodysplastic Syndrome
|
azacitidine
decitabine
C3
U2AF1 mutation
|
Myelodysplastic Syndrome
|
decitabine
HPB-092
D
U2AF1 mutation
|
Acute Myelogenous Leukemia
|
HPB-092
cytarabine/daunorubicin liposomal formulation
C3
U2AF1 mutation
|
Acute Myelogenous Leukemia
|
cytarabine/daunorubicin liposomal formulation
cytarabine
C3
U2AF1 mutation
|
Acute Myelogenous Leukemia
|
cytarabine
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