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BIOMARKER:

SMO D473H

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Other names: SMO, Smoothened Frizzled Class Receptor, Smoothened Seven Transmembrane Spanning Receptor, Smoothened Frizzled Family Receptor, Frizzled Family Member 11, Smoothened Homolog, Protein Gx, SMOH, Seven Transmembrane Helix Receptor, Smoothened (Drosophila) Homolog, Smoothened Homolog (Drosophila), FZD11, CRJS, Gx
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Include preclinical:
Basal Cell Carcinoma
Medulloblastoma
sonidegib
vismodegib
IPI 926 oral