^
    BIOMARKER:

    PTPN11 mutation

    i
    Other names: PTPN11, Protein Tyrosine Phosphatase Non-Receptor Type 11, Tyrosine-Protein Phosphatase Non-Receptor Type 11, Protein-Tyrosine Phosphatase 1D, Protein-Tyrosine Phosphatase 2C, SH-PTP2, SH-PTP3, PTP-1D, PTP2C, Protein Tyrosine Phosphatase Non-Receptor Type 11, Noonan Syndrome 1, METCDS, PTP-2C, SHPTP2, BPTP3, SHP-2, JMML, SHP2, Shp2, CFC, NS1




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    Include preclinical:
    Acute Myelogenous Leukemia
    Juvenile Myelomonocytic Leukemia
    Non Small Cell Lung Cancer
    HIA + azacitidine
    HDA + azacitidine
    cytarabine + daunorubicin + mitoxantrone
    LY3009120
    venetoclax + ABBV 075
    trametinib
    nivolumab + ipilimumab
    dasatinib
    venetoclax
    ivosidenib
    gilteritinib