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BIOMARKER:

PLK1 overexpression

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Other names: PLK1, Polo Like Kinase 1, Serine/Threonine-Protein Kinase PLK1, Serine/Threonine-Protein Kinase 13, Polo-Like Kinase 1, STPK13, PLK-1, Cell Cycle Regulated Protein Kinase, Polo-Like Kinase (Drosophila), Polo (Drosophia)-Like Kinase




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Include preclinical:
Hormone Receptor Positive Breast Cancer
Renal Cell Carcinoma
Colorectal Cancer
Estrogen Receptor Positive Breast Cancer
Lung Cancer
palbociclib
sunitinib
anastrozole
trametinib + pralsetinib
Immunotherapy + PLK1 inhibitor