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    BIOMARKER:

    PIK3CA E545K

    i
    Other names: PIK3CA, Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha, Phosphoinositide-3-kinase, catalytic, alpha polypeptide, Serine/threonine protein kinase PIK3CA, PtdIns-3-kinase subunit P110-alpha, PI3K-alpha, Phosphatidylinositol-4,5-bisphosphate 3-kinase 110 KDa catalytic subunit alpha, Phosphatidylinositol 3-kinase, Catalytic, 110-KD, alpha, PI3-kinase P110 subunit alpha, PI3-kinase subunit alpha, PtdIns-3-kinase subunit alpha, PI3Kalpha, P110alpha, PI3K




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    Include preclinical:
    Breast Cancer
    Ovarian Cancer
    HER2 Negative Breast Cancer
    Cervical Cancer
    Gastric Cancer
    Hepatocellular Cancer
    Hormone Receptor Positive Breast Cancer
    Colorectal Cancer
    Non Small Cell Lung Cancer
    HER2 Positive Breast Cancer
    Thyroid Gland Papillary Carcinoma
    Squamous Cell Carcinoma of Head and Neck
    Melanoma
    CYH33
    pembrolizumab
    TAS-117
    olaparib + durvalumab + capivasertib
    MK-2206
    RTB101
    BMS-722782
    trametinib
    GDC-0941
    rigosertib
    GDC-0032
    vemurafenib
    alpelisib
    abemaciclib + RLY-2608
    palbociclib + RLY-2608
    cetuximab
    RLY-2608
    osimertinib
    lapatinib
    ado-trastuzumab emtansine
    trastuzumab + lapatinib