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    BIOMARKER:

    PIK3CA E542K

    i
    Other names: PIK3CA, Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha, Phosphoinositide-3-kinase, catalytic, alpha polypeptide, Serine/threonine protein kinase PIK3CA, PtdIns-3-kinase subunit P110-alpha, PI3K-alpha, Phosphatidylinositol-4,5-bisphosphate 3-kinase 110 KDa catalytic subunit alpha, Phosphatidylinositol 3-kinase, Catalytic, 110-KD, alpha, PI3-kinase P110 subunit alpha, PI3-kinase subunit alpha, PtdIns-3-kinase subunit alpha, PI3Kalpha, P110alpha, PI3K




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    Include preclinical:
    HER2 Positive Breast Cancer
    Squamous Cell Carcinoma of Head and Neck
    Soft Tissue Sarcoma
    Lung Adenocarcinoma
    Breast Cancer
    Colorectal Cancer
    Gastric Cancer
    trastuzumab
    PF-05212384 + trastuzumab-pkrb
    crizotinib
    GDC-0980
    trametinib + pazopanib
    cetuximab
    CYH33
    GDC-0032
    RTB101