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BIOMARKER:
PDGFRA mutation
i
Other names:
Platelet Derived Growth Factor Receptor Alpha, Platelet-Derived Growth Factor Receptor Alpha Polypeptide, Alpha-Type Platelet-Derived Growth Factor Receptor, CD140 Antigen-Like Family Member A, CD140a Antigen, PDGF-R-Alpha, PDGFR-2, PDGFR2, Alpha Platelet-Derived Growth Factor Receptor, Platelet-Derived Growth Factor Alpha Receptor, PDGFR-Alpha, RHEPDGFRA, CD140A
Associations
(8)
News
Trials
A2 | Sensitive
B | Sensitive
C2 | Sensitive
C3 | Sensitive
D | Sensitive
A2 | Resistant
B | Resistant
C2 | Resistant
C3 | Resistant
D | Resistant
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Include preclinical:
Drug categories
Tyrosine Kinase Inhibitors
Immunotherapy
Epigenetics
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Gastrointestinal Stromal Tumor
Non Small Cell Lung Cancer
Gastric Cancer
imatinib
A2
PDGFRA mutation
|
Gastrointestinal Stromal Tumor
|
imatinib
B
PDGFRA mutation
|
Gastric Cancer
|
imatinib
avapritinib
C2
PDGFRA mutation
|
Gastrointestinal Stromal Tumor
|
avapritinib
nintedanib
C3
PDGFRA mutation
|
Non Small Cell Lung Cancer
|
nintedanib
ripretinib
B
PDGFRA mutation
|
Gastrointestinal Stromal Tumor
|
ripretinib
Immunotherapy
C3
PDGFRA mutation
|
Non Small Cell Lung Cancer
|
Immunotherapy
AZD1775
D
PDGFRA mutation
|
Gastrointestinal Stromal Tumor
|
AZD1775
AZD1775 + avapritinib
D
PDGFRA mutation
|
Gastrointestinal Stromal Tumor
|
AZD1775 + avapritinib
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