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BIOMARKER:

PDGFRA mutation

i
Other names: Platelet Derived Growth Factor Receptor Alpha, Platelet-Derived Growth Factor Receptor Alpha Polypeptide, Alpha-Type Platelet-Derived Growth Factor Receptor, CD140 Antigen-Like Family Member A, CD140a Antigen, PDGF-R-Alpha, PDGFR-2, PDGFR2, Alpha Platelet-Derived Growth Factor Receptor, Platelet-Derived Growth Factor Alpha Receptor, PDGFR-Alpha, RHEPDGFRA, CD140A




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Include preclinical:
Gastrointestinal Stromal Tumor
Non Small Cell Lung Cancer
Gastric Cancer
imatinib
avapritinib
nintedanib
ripretinib
Immunotherapy
AZD1775
AZD1775 + avapritinib