Group by Gene: Include preclinical: Serine-Threonine Kinase Inhibitors Threonine-Tyrosine Kinase Inhibitors Chemotherapy Hormone Therapy PARP Inhibitors Immune Checkpoint Inhibitors Immunotherapy Tyrosine Kinase Inhibitors CD Protein Inhibitors Epigenetics Other PI3 Kinase Inhibitors DNA | Topoisomerase II inhibitor, Tubulin polymerization promoter carboplatin + pegylated liposomal doxorubicin | PD1 inhibitor pembrolizumab | PARP inhibitor olaparib | VEGF-A inhibitor bevacizumab | MEK inhibitor, BRAF inhibitor trametinib + dabrafenib | MEK inhibitor trametinib | WEE1 inhibitor AZD1775 | ALK inhibitor crizotinib | Selective estrogen receptor degrader fulvestrant | Aromatase inhibitor, Microtubule stabilizer, Tubulin polymerization promoter carboplatin + docetaxel + letrozole | Microtubule stabilizer, Tubulin polymerization promoter carboplatin + docetaxel | Aromatase inhibitor, Topoisomerase II inhibitor, Tubulin polymerization promoter carboplatin + letrozole + pegylated liposomal doxorubicin | cRAF inhibitor, MEK inhibitor, BRAF inhibitor, FAK inhibitor VS-6766 + VS-6063 | VS-6766 + VS-4718 | Chk1 inhibitor, Chk2 inhibitor ACR-368 | MEK inhibitor, PTPN11 inhibitor binimetinib + PF-07284892 | Chk1 inhibitor, Chk2 inhibitor, PARP inhibitor olaparib + ACR-368 | cRAF inhibitor, MEK inhibitor, BRAF inhibitor binimetinib + encorafenib | Tubulin polymerization promoter carboplatin | DNA synthesis inhibitor cisplatin | FAK inhibitor VS-4718 | Chk1 inhibitor, Chk2 inhibitor, PI3K inhibitor, mTOR inhibitor ACR-368 + LY3023414 | pan-RAF inhibitor LY3009120 |
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No biomarker | |||||||||||||||||||||||
BRCA1 mutation | |||||||||||||||||||||||
KRAS G12D | |||||||||||||||||||||||
KRAS G12V | |||||||||||||||||||||||
KRAS G12A | |||||||||||||||||||||||
BRCA1 deletion | |||||||||||||||||||||||
KRAS wild-type | |||||||||||||||||||||||
BRCA2 mutation | |||||||||||||||||||||||
BRCA2 deletion | |||||||||||||||||||||||
BRAF V600E | |||||||||||||||||||||||
BRAF L485-P490 deletion | |||||||||||||||||||||||
SERPINE1 expression | |||||||||||||||||||||||
GOPC-ROS1 fusion | |||||||||||||||||||||||
ER Y537N | |||||||||||||||||||||||
TMB-H + MSH6 F1088fs | |||||||||||||||||||||||
Choline elevation | |||||||||||||||||||||||
PRMT1 underexpression | |||||||||||||||||||||||
RAF1 V207G |