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BIOMARKER:
NUP98-NSD1 fusion + FLT3-ITD mutation
i
Other names:
NSD1, Nuclear Receptor Binding SET Domain Protein 1, ARA267, KMT3B, Histone-Lysine N-Methyltransferase H3 Lysine-36 Specific, Nuclear Receptor-Binding SET Domain-Containing Protein 1, Androgen Receptor-Associated Protein Of 267 KDa, Androgen Receptor Coactivator 267 KDa Protein, NR-Binding SET Domain-Containing Protein, Lysine N-Methyltransferase 3B, H3-K36-HMTase, Histone-Lysine N-Methyltransferase H3 Lysine-36 And H4 Lysine-20 Specific, Truncated Nuclear Receptor Binding SET Domain Protein 1,
Associations
(3)
News
Trials
C3 | Sensitive
D | Sensitive
C3 | Resistant
D | Resistant
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Include preclinical:
Drug categories
Tyrosine Kinase Inhibitors
Serine-Threonine Kinase Inhibitors
Chemotherapy
Other
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Acute Myelogenous Leukemia
sorafenib
C3
NUP98-NSD1 fusion + FLT3-ITD mutation
|
Acute Myelogenous Leukemia
|
sorafenib
mitoxantrone
D
NUP98-NSD1 fusion + FLT3-ITD mutation
|
Acute Myelogenous Leukemia
|
mitoxantrone
SNDX-5613
D
NUP98-NSD1 fusion + FLT3-ITD mutation
|
Acute Myelogenous Leukemia
|
SNDX-5613
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