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BIOMARKER:

MSI-H/dMMR + MLH1 deletion + PMS2 deletion

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Other names: MSI | Microsatellite instability, MLH1, COCA2, FCC2, HNPCC, HNPCC2, MutL homolog 1, PMS2, PMS1 Homolog 2, Mismatch Repair System Component, PMS1 Homolog 2, Mismatch Repair Protein, Mismatch Repair Endonuclease PMS2, DNA Mismatch Repair Protein PMS2, PMS1 Protein Homolog 2, PMSL2, PMS2 Postmeiotic Segregation Increased 2, Postmeiotic Segregation Increased 2 Nirs Variant 6, PMS2 Postmeiotic Segregation Increased 2, HNPCC4, PMS2CL, MLH4
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Colorectal Cancer
Esophageal Adenocarcinoma
pembrolizumab
Immunotherapy