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BIOMARKER:
MSH2 mutation
i
Other names:
MSH2, MutS Homolog 2, HMSH2, MutS (E. Coli) Homolog 2, MutS Homolog 2, Nonpolyposis Type 1, DNA Mismatch Repair Protein Msh2, MutS Protein Homolog 2, HNPCC1, HNPCC, LCFS2, COCA1, FCC1
Associations
(7)
News
Trials
C2 | Sensitive
C3 | Sensitive
C4 | Sensitive
C2 | Resistant
C3 | Resistant
C4 | Resistant
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Drug categories
Immune Checkpoint Inhibitors
Immunotherapy
CD Protein Inhibitors
Chemotherapy
DNA
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Gastric Cancer
Adrenal Cortex Carcinoma
Pancreatic Ductal Adenocarcinoma
Urothelial Cancer
Rectal Cancer
Colorectal Cancer
nivolumab + ipilimumab
C3
MSH2 mutation
|
Urothelial Cancer
|
nivolumab + ipilimumab
C3
MSH2 mutation
|
Rectal Cancer
|
nivolumab + ipilimumab
pembrolizumab
C4
MSH2 mutation
|
Adrenal Cortex Carcinoma
|
pembrolizumab
durvalumab
C2
MSH2 mutation
|
Gastric Cancer
|
durvalumab
FOLFIRINOX
C3
MSH2 mutation
|
Pancreatic Ductal Adenocarcinoma
|
FOLFIRINOX
tremelimumab
C2
MSH2 mutation
|
Gastric Cancer
|
tremelimumab
5-fluorouracil + oxaliplatin
C3
MSH2 mutation
|
Colorectal Cancer
|
5-fluorouracil + oxaliplatin
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