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BIOMARKER:
MSH2 deletion
i
Other names:
MSH2, MutS Homolog 2, HMSH2, MutS (E. Coli) Homolog 2, MutS Homolog 2, Nonpolyposis Type 1, DNA Mismatch Repair Protein Msh2, MutS Protein Homolog 2, HNPCC1, HNPCC, LCFS2, COCA1, FCC1
Associations
(4)
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Trials
C3 | Sensitive
C4 | Sensitive
D | Sensitive
C3 | Resistant
C4 | Resistant
D | Resistant
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Include preclinical:
Drug categories
CD Protein Inhibitors
Immune Checkpoint Inhibitors
Immunotherapy
Chemotherapy
DNA
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Endometrial Adenocarcinoma
Prostate Cancer
Urothelial Cancer
Glioblastoma
nivolumab
C3
MSH2 deletion
|
Endometrial Adenocarcinoma
|
nivolumab
C3
MSH2 deletion
|
Prostate Cancer
|
nivolumab
durvalumab + MEDI0680
C4
MSH2 deletion
|
Urothelial Cancer
|
durvalumab + MEDI0680
temozolomide
D
MSH2 deletion
|
Glioblastoma
|
temozolomide
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