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    BIOMARKER:

    MLL rearrangement

    i
    Other names: HTRX1, HTRX, MLL1A, Mixed Lineage Leukemia 1, Myeloid/Lymphoid Or Mixed-Lineage Leukemia Protein 1, CXXC7, MLL1, TRX1, Zinc Finger Protein HRX, Trithorax-Like Protein, ALL-1, Lysine (K)-Specific Methyltransferase 2A, CXXC-Type Zinc Finger Protein 7, Histone-Lysine N-Methyltransferase 2A, Myeloid/Lymphoid Or Mixed-Lineage Leukemia, Lysine Methyltransferase 2A, MLL, Myeloid/Lymphoid Or Mixed-Lineage Leukemia, KMT2A




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    Include preclinical:
    Acute Myelogenous Leukemia
    Leukemia
    Acute Lymphocytic Leukemia
    B Acute Lymphoblastic Leukemia
    SNDX-5613
    CB-659
    irinotecan
    doxorubicin hydrochloride
    OSE-127
    D0060-319
    selinexor + KO-539
    SNDX-5613 + ORY-1001
    VTP-50469 + EPZ-5676