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    BIOMARKER:

    MLL-AFF1 fusion

    i
    Other names: HTRX1, HTRX, MLL1A, Mixed Lineage Leukemia 1, Myeloid/Lymphoid Or Mixed-Lineage Leukemia Protein 1, CXXC7, MLL1, TRX1, Zinc Finger Protein HRX, Trithorax-Like Protein, ALL-1, Lysine (K)-Specific Methyltransferase 2A, CXXC-Type Zinc Finger Protein 7, Histone-Lysine N-Methyltransferase 2A, Myeloid/Lymphoid Or Mixed-Lineage Leukemia, Lysine Methyltransferase 2A, MLL, Myeloid/Lymphoid Or Mixed-Lineage Leukemia, KMT2A, AFF1, AF4/FMR2 Family Member 1, ALL1-Fused Gene From Chromosome 4 Protein, Pre-B-C
    Associations
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    Include preclinical:
    Acute Lymphocytic Leukemia
    B Acute Lymphoblastic Leukemia
    etoposide oral
    venetoclax
    panobinostat
    selumetinib + GS-9973
    GS-9973