Group by Gene: Include preclinical: CD Protein Inhibitors Immune Checkpoint Inhibitors Immunotherapy Chemotherapy DNA Tyrosine Kinase Inhibitors Cytokine MDM2/MDMX Other | nivolumab | PD1 inhibitor retifanlimab-dlwr | pembrolizumab | PD-L1 inhibitor avelumab | Topoisomerase II inhibitor, DNA inhibitor, DNA synthesis inhibitor cisplatin + etoposide oral | DNA synthesis inhibitor cisplatin | Tubulin polymerization promoter carboplatin | Topoisomerase I inhibitor topotecan | Multi-tyrosine kinase inhibitor pazopanib | GM-CSF agonist talimogene laherparepvec | PD1 inhibitor, CTLA4 inhibitor nivolumab + ipilimumab | CTLA4 inhibitor ipilimumab | TLR9 agonist AST-008 | Immunostimulant ITI-3000 | MDM2 inhibitor KRT-232 | RAIN-32 | Immunotherapy Immunotherapy | Chemotherapy CAV | EP | Topoisomerase II inhibitor, Tubulin polymerization promoter, DNA inhibitor carboplatin + etoposide oral | DLL3-targeted antibody-drug conjugate, DNA replication inhibitor rovalpituzumab tesirine | CD56-targeted antibody-drug conjugate, Microtubule inhibitor McSAF 03 |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
No biomarker | ||||||||||||||||||||||
PD-L1 negative | ||||||||||||||||||||||
PD-L1 expression | ||||||||||||||||||||||
NTRK1 mutation | ||||||||||||||||||||||
PD-1 expression | ||||||||||||||||||||||
TP53 wild-type | ||||||||||||||||||||||
DLL3 expression | ||||||||||||||||||||||
NCAM1 expression | ||||||||||||||||||||||
NKX2-1 expression | ||||||||||||||||||||||
ARID2 mutation |