^
    BIOMARKER:

    MDM2 amplification

    i
    Other names: MDM2, HDM2, MGC5370, MDM2 proto-oncogene, E3 ubiquitin protein ligase




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    Include preclinical:
    Solid Tumor
    Liposarcoma
    Biliary Tract Cancer
    Cholangiocarcinoma
    Ampulla of Vater Carcinoma
    Sarcoma
    Hormone Receptor Positive Breast Cancer
    Glioblastoma
    Mucosal Melanoma
    Gastric Adenocarcinoma
    Diffuse Large B Cell Lymphoma
    Melanoma
    Soft Tissue Sarcoma
    Triple Negative Breast Cancer
    BI 907828
    RAIN-32
    APG-115
    BI 907828 + BI 754091
    pembrolizumab
    nivolumab + ipilimumab
    nivolumab
    ipilimumab
    eribulin mesylate
    Immunotherapy
    R-CHOP