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BIOMARKER:
MCL1 underexpression
i
Other names:
MCL1, MCL1 Apoptosis Regulator BCL2 Family Member, Induced Myeloid Leukemia Cell Differentiation Protein Mcl-1, Myeloid Cell Leukemia Sequence 1 (BCL2-Related), MCL1 BCL2 Family Apoptosis Regulator, Bcl-2-Related Protein EAT/Mcl1, Myeloid Cell Leukemia 1, Bcl-2-Like Protein 3, Bcl2-L-3, Mcl1/EAT, BCL2L3, BCL2 Family Apoptosis Regulator, Myeloid Cell Leukemia ES, MCL1-ES, MCL1L, MCL1S, Mcl-1, EAT, TM
Associations
(4)
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Trials
C3 | Sensitive
D | Sensitive
C3 | Resistant
D | Resistant
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Include preclinical:
Drug categories
Chemotherapy
DNA
BCL Inhibitors
Proteasome Inhibitors
Serine-Threonine Kinase Inhibitors
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Small Cell Lung Cancer
Multiple Myeloma
T Acute Lymphoblastic Leukemia
cisplatin
C3
MCL1 underexpression
|
Small Cell Lung Cancer
|
cisplatin
venetoclax
D
MCL1 underexpression
|
Multiple Myeloma
|
venetoclax
bortezomib + A-1331852
D
MCL1 underexpression
|
Multiple Myeloma
|
bortezomib + A-1331852
venetoclax + NBL-001
D
MCL1 underexpression
|
T Acute Lymphoblastic Leukemia
|
venetoclax + NBL-001
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