^
    CANCER:

    Lung Adenocarcinoma





    Show legend
    Group by Gene:
    Include preclinical:

    crizotinib
    alectinib
    		0
    ALK inhibitor
    ceritinib
    ensartinib
    ALK inhibitor
    osimertinib
    gefitinib
    erlotinib
    aumolertinib
    icotinib
    		1
    EGFR inhibitor
    furmonertinib
    tarloxotinib bromide
    erlotinib + gefitinib + icotinib
    icotinib + aumolertinib
    osimertinib + gefitinib
    EGFR inhibitor
    pembrolizumab
    cemiplimab-rwlc
    nivolumab
    		2
    PD1 inhibitor
    toripalimab-tpzi
    sintilimab
    camrelizumab
    PD1 inhibitor
    nintedanib
    cabozantinib tablet
    		3
    Multi-tyrosine kinase inhibitor
    anlotinib
    vandetanib
    midostaurin
    cabozantinib capsule
    4
    Bcl2 inhibitor, Tubulin inhibitor
    albumin-bound paclitaxel
    5
    RET inhibitor
    selpercatinib
    pralsetinib
    savolitinib
    		6
    c-MET inhibitor
    tepotinib
    capmatinib
    bevacizumab + erlotinib
    		7
    VEGF-A inhibitor, EGFR inhibitor
    bevacizumab + osimertinib
    bevacizumab + cetuximab
    bevacizumab + icotinib
    osimertinib + anlotinib
    anlotinib + icotinib
    		8
    EGFR inhibitor, Multi-tyrosine kinase inhibitor
    anlotinib + furmonertinib
    erlotinib + cabozantinib capsule
    osimertinib + cabozantinib tablet
    gefitinib + anlotinib
    9
    VEGF-A inhibitor
    bevacizumab
    brigatinib
    crizotinib + osimertinib
    		10
    ALK inhibitor, EGFR inhibitor
    cetuximab + brigatinib
    crizotinib + icotinib
    alectinib + brigatinib
    11
    CDK4 inhibitor, CDK6 inhibitor
    abemaciclib
    12
    MEK inhibitor, BRAF inhibitor
    trametinib + dabrafenib
    13
    VEGFR-2 inhibitor
    rivoceranib
    atezolizumab
    		14
    PD-L1 inhibitor
    durvalumab
    PD-L1 inhibitor
    15
    EGFR inhibitor, PARP inhibitor
    olaparib + gefitinib
    16
    PARP inhibitor
    olaparib
    talazoparib
    17
    PD1 inhibitor, IDO1 inhibitor
    pembrolizumab + INCB024360
    18
    DNA synthesis inhibitor
    cisplatin
    19
    MEK inhibitor
    trametinib
    AZD8330
    20
    pan-HER inhibitor
    dacomitinib
    21
    BRAF inhibitor, BRAF V600E inhibitor
    vemurafenib
    22
    VEGF-A inhibitor, pan-HER inhibitor
    bevacizumab + dacomitinib
    23
    PIK3CA inhibitor
    alpelisib
    24
    mTOR inhibitor, Multi-tyrosine kinase inhibitor
    everolimus + vandetanib
    25
    TrkB receptor inhibitor, TrkC kinase inhibitor, TrkA receptor inhibitor
    larotrectinib
    26
    PD1 inhibitor, Multi-tyrosine kinase inhibitor
    pembrolizumab + anlotinib
    27
    VEGFR-2 inhibitor, PD1 inhibitor
    toripalimab-tpzi + rivoceranib
    28
    HER2 inhibitor, HER2 dimerization inhibitor
    trastuzumab + pertuzumab
    29
    PD1 inhibitor, PARP inhibitor
    sintilimab + niraparib
    30
    mTORC1 inhibitor, mTORC2 inhibitor
    CB-228
    31
    PD1 inhibitor, CTLA4 inhibitor
    nivolumab + ipilimumab
    32
    HER2-targeted antibody-drug conjugate, Topoisomerase I inhibitor
    fam-trastuzumab deruxtecan-nxki
    33
    VEGFR-2 inhibitor, EGFR inhibitor
    osimertinib + ramucirumab
    34
    KRAS G12C inhibitor
    sotorasib
    adagrasib
    35
    ALK inhibitor, BRAF inhibitor, BRAF V600E inhibitor
    crizotinib + vemurafenib
    afatinib
    cetuximab + afatinib
    pyrotinib
    		36
    HER2 inhibitor, HER4 inhibitor, EGFR inhibitor
    afatinib + pyrotinib
    osimertinib + afatinib
    neratinib
    afatinib + gefitinib
    37
    Notch inhibitor, EGFR inhibitor
    Notch inhibitor + osimertinib
    38
    THF dehydrogenase inhibitor, DNA synthesis inhibitor, Thymidylate synthase inhibitor
    cisplatin + pemetrexed
    39
    PD-L1 inhibitor, CTLA4 inhibitor
    durvalumab + tremelimumab
    lorlatinib
    		40
    ROS1 inhibitor, ALK inhibitor
    iruplinalkib
    SAF-189
    41
    THF dehydrogenase inhibitor, Thymidylate synthase inhibitor
    pemetrexed
    42
    HER2-targeted antibody-drug conjugate, Microtubule inhibitor
    ado-trastuzumab emtansine
    43
    TrkB receptor inhibitor, TrkC kinase inhibitor, ROS1 inhibitor, TrkA receptor inhibitor, ALK inhibitor, JAK2 inhibitor, TNK2 inhibitor
    entrectinib
    crizotinib + entrectinib
    44
    MEK inhibitor, BRAF inhibitor, EGFR inhibitor
    trametinib + osimertinib + dabrafenib
    cetuximab + trametinib + dabrafenib
    45
    VEGF-A inhibitor, HER2 inhibitor, HER4 inhibitor, EGFR inhibitor
    bevacizumab + afatinib
    bevacizumab + pyrotinib
    46
    c-MET inhibitor, CSF-1R inhibitor, Src kinase inhibitor
    TPX-0022
    47
    VEGFR-2 inhibitor, HER2 inhibitor, HER4 inhibitor, EGFR inhibitor
    afatinib + rivoceranib
    48
    THF dehydrogenase inhibitor, Tubulin polymerization promoter, Thymidylate synthase inhibitor
    carboplatin + pemetrexed
    49
    mTORC1 inhibitor, Glutaminase inhibitor, mTORC2 inhibitor
    CB-228 + CB-839
    50
    HER2 inhibitor, HER4 inhibitor, EGFR inhibitor, Multi-tyrosine kinase inhibitor
    afatinib + anlotinib
    51
    HER2 inhibitor, HER4 inhibitor, PD1 inhibitor, EGFR inhibitor, Multi-tyrosine kinase inhibitor
    nivolumab + anlotinib + pyrotinib
    52
    PD-L1 inhibitor, HER2 inhibitor, HER4 inhibitor, EGFR inhibitor
    atezolizumab + afatinib
    53
    pan-RAF inhibitor, Multi-tyrosine kinase inhibitor
    sorafenib
    54
    c-MET inhibitor, EGFR inhibitor
    osimertinib + savolitinib
    55
    RET inhibitor, ALK inhibitor
    crizotinib + pralsetinib
    56
    JAK1 inhibitor, JAK2 inhibitor
    ruxolitinib
    57
    ROS1 inhibitor, PD1 inhibitor, ALK inhibitor
    lorlatinib + camrelizumab
    58
    PD-L1 inhibitor, VEGF-A inhibitor
    bevacizumab + atezolizumab
    59
    pan-HER inhibitor, Multi-tyrosine kinase inhibitor, PARP inhibitor
    olaparib + anlotinib + dacomitinib
    60
    HER2 inhibitor, HER4 inhibitor, ROS1 inhibitor, ALK inhibitor, EGFR inhibitor
    afatinib + lorlatinib
    61
    ROS1 inhibitor, ALK inhibitor, PARP inhibitor
    olaparib + lorlatinib
    62
    Glutamine antagonist
    DRP-104
    63
    HDAC inhibitor, ALK inhibitor, EGFR inhibitor
    brigatinib + vorinostat
    64
    EGFR antagonist, c-MET inhibitor
    CKD-702
    gefitinib + selumetinib
    		65
    MEK inhibitor, EGFR inhibitor
    gefitinib + CI-1040
    trametinib + erlotinib
    66
    Alkylating agent
    STAR-001
    67
    MEK inhibitor, AKT inhibitor
    selumetinib + MK-2206
    68
    HER2 inhibitor, HER4 inhibitor, pan-EGFR inhibitor
    poziotinib
    69
    HER2 inhibitor, HER2-targeted antibody-drug conjugate, EGFR inhibitor, Microtubule inhibitor
    ado-trastuzumab emtansine + mobocertinib
    70
    HER2 inhibitor, EGFR inhibitor
    mobocertinib
    lapatinib
    71
    STAT5 inhibitor, MEK inhibitor, JAK2 inhibitor, FLT3 inhibitor
    trametinib + CEP-701
    72
    FGFR inhibitor
    infigratinib
    ABSK091
    73
    MEK2 inhibitor, MEK1 inhibitor
    REC-4881
    74
    PI3K inhibitor, mTOR inhibitor
    PF-04691502
    GSK2126458
    75
    PRMT5 inhibitor, KRAS G12C inhibitor
    sotorasib + TNG908
    76
    STAT3 inhibitor
    TTI-101 oral
    77
    AXL inhibitor, PD1 inhibitor
    pembrolizumab + BGB324
    78
    CDK4 inhibitor, EGFR inhibitor, CDK6 inhibitor
    osimertinib + abemaciclib
    79
    KRAS G12C inhibitor, Multi-tyrosine kinase inhibitor
    midostaurin + adagrasib
    sotorasib + midostaurin
    80
    VEGFR-2 inhibitor, AXL inhibitor, Tyrosine kinase inhibitor, FLT3 inhibitor
    KC1036
    81
    TrkB receptor inhibitor, TrkC kinase inhibitor, TrkA receptor inhibitor, EGFR inhibitor
    osimertinib + larotrectinib
    82
    ROS1 inhibitor, Trk inhibitor, ALK inhibitor, Multi-tyrosine kinase inhibitor
    repotrectinib
    83
    ATR inhibitor, PARP inhibitor
    olaparib + VE-821
    84
    MYC inhibitor
    OMO-103
    85
    Tubulin polymerization inhibitor
    vinorelbine tartrate
    86
    Topoisomerase II inhibitor
    doxorubicin hydrochloride
    87
    VEGFR inhibitor, PDGFR inhibitor, c-KIT inhibitor
    sunitinib
    88
    Tubulin polymerization promoter, Bcl2 inhibitor
    paclitaxel
    89
    Topoisomerase II inhibitor, DNA inhibitor
    etoposide oral
    90
    Hedgehog cell-signalling pathway inhibitor
    cyclopamine
    91
    CLDN18.2-targeted antibody-drug conjugate, DNA replication inhibitor
    SOT102
    92
    MAT2A inhibitor
    IDE397
    93
    MEK inhibitor, MDM2 inhibitor
    trametinib + RAIN-32
    94
    CDK12 inhibitor, EGFR inhibitor, CDK13 inhibitor
    osimertinib + AU-16770
    osimertinib + AU-15506
    everolimus + ARS-1620
    		95
    KRAS G12C inhibitor, mTOR inhibitor
    everolimus + sotorasib
    everolimus + adagrasib
    96
    Bcr-abl tyrosine kinase inhibitor, Src kinase inhibitor
    bosutinib
    97
    MEK inhibitor, Multi-tyrosine kinase inhibitor
    trametinib + midostaurin
    98
    EGFR inhibitor, γ-secretase inhibitor
    gefitinib + nirogacestat
    99
    Bcr-abl tyrosine kinase inhibitor, Src kinase inhibitor, c-KIT inhibitor, PDGFR β antagonist, EphA2 receptor antagonist
    dasatinib
    100
    RNA polymerase inhibitor, Alkylating agent, Apoptosis stimulant
    lurbinectedin
    101
    HSP90 inhibitor, mTOR inhibitor
    sirolimus + IPI-504
    102
    Immunotherapy
    Immunotherapy
    103
    Immunotherapy, Angiogenesis inhibitor
    Immunotherapy + Angiogenesis inhibitor
    104
    KRAS inhibitor
    KRAS inhibitor
    105
    FASN inhibitor
    FASN inhibitor
    106
    Tyrosine kinase inhibitor
    Tyrosine kinase inhibitor
    107
    Trk inhibitor
    Trk inhibitor
    ABCP
    		108
    Chemotherapy
    GC
    DP
    109
    CFTR potentiator
    CFTR potentiator
    110
    Angiogenesis inhibitor
    Angiogenesis inhibitor
    No biomarker
    EGFR mutation
    EGFR L858R
    EGFR exon 19 deletion
    EGFR exon 21 mutation
    EGFR exon 20 insertion
    EGFR T790M
    EGFR exon 19 insertion
    EGFR T854A
    EGFR V769A
    EGFR E709A + EGFR G719C
    EGFR L718Q
    EGFR exon 19 deletion + EGFR C797S
    EGFR L861Q + EGFR G719X
    EGFR I744_K745insKIPVAI
    EGFR T854A + EGFR T790M
    EGFR G719S
    EGFR exon 19 deletion + EGFR T790M + EGFR C797S
    EGFR E709_T710delinsD
    EGFR T790M + EGFR C797S
    EGFR wild-type
    EGFR exon 19 mutation
    EGFR D770_N771insSVD
    EGFR exon 18-25 duplication
    EGFR L861Q
    EGFR G719X
    EGFR L747P
    EGFR G729A + EGFR L858R
    EGFR exon 19 deletion + EGFR T790L
    EGFR overexpression
    EGFR L858R + EGFR V843I
    EGFR G719A + EGFR S768I
    EGFR G719C + EGFR S768I
    EGFR L858R + EGFR R776H
    EGFR G719S + EGFR L861Q
    EGFR Q787Q
    EGFR L858R + EGFR exon 19 deletion
    EGFR expression
    EGFR L858R + EGFR A871G
    EGFR L833V + EGFR H835L
    EGFR A767_V769dup
    EGFR C797S
    EGFR V786M
    EGFR G719A + EGFR L833V
    EGFR L858R + EGFR T790M
    EGFR S768_D770dupSVD
    EGFR N771_P772insVal
    EGFR T790I
    EGFR exon 19 deletion + EGFR G724S + EGFR T790M
    EGFR exon 21 deletion
    EGFR G719S + EGFR S768I
    EGFR L858R + EGFR L718Q
    EGFR exon 19 deletion + EGFR K754E
    EGFR G724S + EGFR R776H
    EGFR T263P
    EGFR exon 18 mutation
    EGFR amplification
    EGFR N771delinsKG
    EGFR G719X + EGFR S768I
    EGFR exon 19 deletion + EGFR T790M
    EGFR A859T
    EGFR exon 18 deletion
    EGFR L858R + EGFR M766Q
    EGFR C797S + EGFR T790M + EGFR L858R
    EGFR exon 19 deletion + EGFR L861Q
    EGFR A763_Y764insFQEA
    EGFR E746_S752delinsV
    EGFR T790M + EGFR L833V + EGFR H835L
    EGFR T790L
    EGFR M766Q
    EGFR T790M + EGFR S768I + EGFR L858R
    EGFR L747-S752 del
    EGFR L860R
    EGFR L861R
    EGFR mutation + EGFR amplification
    EGFR S768I
    EGFR D761Y
    EGFR S645C + EGFR L858R
    HER-2 exon 20 insertion
    HER-2 amplification
    HER-2 mutation
    HER-2 G778_S779insCPG
    HER-2 G780_P781dupGSP
    HER-2 overexpression
    HER-2 A775_G776insYVMA
    HER-2 V659D
    HER-2 S335C
    HER-2 G776L
    HER-2 D769Y
    HER-2 underexpression
    HER-2 S310F
    HER-2 G778_P780dup
    HER-2 Y772_A775dup
    HER-2 exon 20 YVMA insertion
    HER-2 exon 20G776>VC insertion
    MET exon 14 mutation
    MET amplification
    MET amplification + MET Exon 14 mutation
    MET amplification + MET exon 14 mutation + EGFR exon 20 insertion
    MET H1094Y
    MET F1200I
    MET D1028N
    MET D1010N
    MET Y1021H
    MET overexpression
    ALK positive
    ALK rearrangement
    ALK fusion
    ALK G1202K
    LOC101927285-ALK fusion
    ALK G1202L
    ALK exon 23 C1156Y missense mutation+ LOC101927285-ALK fusion
    ALK C1156Y + ALK I1171T
    EML4-ALK fusion + ALK I1171N
    EML4-ALK variant 2
    EML4-ALK fusion + ALK I1171T
    EML4-ALK rearrangement
    EML4-ALK E13;A20
    EML4-ALK fusion
    EML4-ALK fusion + ALK F1174L + ALK S1189C
    EML4-ALK variant 3
    EML4-ALK L1196M
    EML4-ALK C1156Y
    PD-L1 expression
    KRAS mutation
    EGFR L858R + MET amplification
    BRAF V600E
    KRAS G12C
    EGFR exon 19 deletion + PD-L1 overexpression
    PD-L1 overexpression
    PD-L1 underexpression
    EGFR mutation + PD-L1 expression
    EGFR exon 19 deletion + EGFR T790M + PD-L1 expression
    BRAF mutation
    EGFR exon 19 deletion + MET Amplification + MET D1228V
    BRAF G596V
    KRAS A146V
    EGFR G719A + PD-L1 overexpression
    EGFR exon 19 deletion + MET amplification
    EGFR L858R + MET overexpression
    BRAF V600
    BRAF G469V
    BRAF mutation + MSI-L/dMMR
    EGFR mutation + PD-L1 overexpression
    EGFR exon 19 deletion + MET amplification +  MET D1228H + MET D1228N +  MET D1228Y
    EGFR exon 19 deletion + MET amplification +  MET D1228H + MET D1228N +  MET D1228Y +  MET Y1230C
    KRAS G12V
    EGFR exon 19 deletion + MET amplification
    KRAS G12S
    HER-2 exon 20 insertion + TMB-L + PD-L1 negative
    TP53 mutation
    RET fusion
    EGFR exon 19 deletion + BRAF V600E
    TP53 R333Vfs*12
    BRAF V600E + EGFR expression
    RET rearrangement
    POLD1 E374K
    POLD1 Y956N
    POLD1 C284Y
    EGFR mutation + BRAF V600
    TP53 W146*
    EGFR mutation + BRAF V600E
    EGFR mutation + BRAF G469A
    EGFR exon 19 deletion + BRAF G464A
    TP53 N263D
    KIF5B-RET fusion
    MUTYH Q324H
    BRCA2 mutation
    EGFR C797S + EGFR T790M + EGFR exon 19 deletion + TMB-L
    EGFR L858R + ALK rearrangement
    ROS1 rearrangement
    BRAF E501Q + PD-L1 negative
    PD-L1 overexpression + BRAF V600E
    MET exon 14 mutation + MET amplification + PD-L1 overexpression
    TTF1 expression + PD-L1 expression
    TTF1 expression + PD-L1 overexpression
    ANK2 mutation
    EGFR exon 19 deletion + TP53 exon 8 mutation
    KIF5B-ALK fusion
    ANK2 overexpression
    KIF5B-ALK fusion + ALK L1196M
    PIK3CA E542K
    PIK3CA mutation
    ROS1 rearrangement + ROS1 F2004L
    EGFR wild-type + ALK wild-type
    PD-L1 overexpression + MET exon 14 mutation
    EGFR L858R + TP53 wild-type
    EGFR mutation + TP53 mutation
    EGFR mutation + TP53 exon 6 mutation
    EGFR mutation + TP53 exon 7 mutation
    TMB-H + EGFR exon 19 deletion
    TMB-H + EGFR mutation
    EGFR L858R + TP53 mutation
    EGFR exon 19 deletion + EGFR exon 21 mutation + TP53 mutation
    ROS1 G2032R
    RMST-ALK rearrangement
    CD74-ROS1 F2004L + PD-L1 expression
    CD47-MET fusion
    CD74-ROS1 fusion + TMB-H
    EGFR V843I + KRAS G13D + AKT1 E17K + PD-L1 overexpression
    CD74-NRG1 fusion + EGFR mutation + HER-2 mutation
    ROS1 fusion + NBN mutation
    CCDC85A-ALK fusion
    STRN-ALK fusion
    KIF5B-RET fusion + MET amplification
    RET-MIR4299-MIR8070 fusion + RET amplification
    PD-L1 overexpression + TMB-H + ARID1A F2141fs*59
    EML4-NTRK3 fusion
    KRAS G12C + PD-L1 overexpression
    CD74-ROS1 fusion
    EML4-ALK gene fusion + EGFR exon 19 deletion + EGFR T790M + EGFR C797G
    ERCC2 positive + SYP negative + EGFR exon 21 mutation
    EML4-ALK fusion v1insLTBP1
    SETD3-ALK fusion
    ROS1 rearrangement + PD-L1 overexpression
    LINC01264-RET fusion + SEMA5A-RET fusion + CCDC6-RET fusion
    ATM mutation
    STK11 mutation
    EGFR L858R + EGFR E709X + CTNNB1 mutation
    EML6-ALK fusion + FBXO11-ALK fusion
    SLC3A2-NRG1 fusion
    MET-ATXN7L1 fusion
    KIF5B-MET fusion
    ARAF S214C
    RICTOR amplification
    SQSTM1-NTRK1 fusion
    EML4-ALK fusion + CDK15-ALK fusion
    EGFR-GRB2 fusion
    AKT2 amplification
    COX7A2L-ALK fusion
    KIF13A-RET fusion
    SETD2-ALK fusion + EML4-ALK fusion
    TNIP2-ALK fusion
    KIF5B-RET fusion + EGFR exon 19 deletion
    PRDX1 exon 5-NTRK1 exon 12 fusion
    ALK positive + EML4-ALK fusion + TP53 mutation
    KIDINS220-ALK fusion
    SDC4-ROS1 fusion
    EML4-ALK + ALK G1202R + LIPI-NTRK1
    UGP2-ALK fusion
    PTPRC expression
    NPTN-NRG1 fusion
    ALK expression + RSRC1-ALK fusion
    TLR8 expression
    CCR5 expression
    POTEE mutation
    ALK rearrangement + EML4-ALK fusion + CCDC148-ALK fusion + PKDCC-ALK fusion + VIT-ALK fusion
    TTF1 expression
    KIF13A-ALK fusion
    EZR-ROS1 fusion
    CCL21 elevation
    SLC35A2 overexpression
    KEAP1 mutation
    LRP1B mutation
    CTSL overexpression
    GIMAP6 overexpression
    TP53 mutation + KRAS mutation
    ARID1A underexpression + EGFR mutation
    CD276 underexpression + EGFR mutation
    PILRA overexpression
    PSTPIP1 overexpression
    MTAP deletion
    MGA mutation + TMB-L
    TTN mutation
    SPTA1 mutation
    EGFR mutation + TSLP underexpression
    PCSK9 underexpression
    PXDNL P1460T
    POLE4 A59E
    PAPPA2 Y1520X
    SCN8A Q225X
    SDC4-NRG1 fusion
    CD74-NRG1 fusion
    STK11 deletion + KRAS mutation
    IFI27 underexpression
    EGFR mutation + MDM4 *32C>A
    OGG1 S326C
    PIK3CA mutation + PTEN deletion
    SNX20 overexpression + PD-L1 overexpression
    SDC4-ROS1 fusion + ROS1-GK fusion
    EGFR exon 19 deletion + BRCA2 mutation
    EGFR L858R + PIK3CA H1047R + PIK3CA E545K
    BRAF V600E + ROS1 fusion
    STRN-ALK fusion + EML4-ALK fusion + EGFR T790M
    NBEA-ALK fusion + EML4-ALK fusion
    PD-L1 overexpression + RET-KIF5B fusion + TP53 mutation + AR mutation + RET rearrangement
    MRPS9-ALK fusion
    PTH2R-ALK fusion
    DCTN1-ALK fusion
    WNK1-ROS1 fusion
    DCTN1-ALK rearrangement + ALK-CLIP4 rearrangement
    ALK-HLA-DRB1 fusion
    LDLR-ROS1 fusion
    ALK-HIP1 fusion
    LTBP1-ALK fusion
    LTBP1-ALK fusion + HIP1-ALK fusion
    TTF1 expression + NAPSA expression + PD-L1 expression + TMB-H
    EGFR L858R + ROS1-ADGRG6 fusion
    SDK1-ALK fusion
    ALK rearrangement + BRCA2 F2801fs
    ALK rearrangement + ALK I1171N + ALK V1180L + BRCA2 F2801fs
    MYH9-ROS1 fusion
    BRAF G466E + NF1 Y2285fs*5 + NF1 Y2640fs*3 + TP53 D281Y
    EGFR exon 19 deletion + EGFR T790M + EGFR C797S + HER-2 amplification
    EML4-ALK fusion + ARID2-ALK fusion
    EML4-ALK fusion + ALK-SSH2 fusion
    NCOR2-NTRK1 fusion + TMB-H
    EGFR L858R + TP53 R273C + HER-2 S442L
    CTNND1-ALK fusion
    KLHL31-LRRC1-ALK fusion
    PMS2 1144+1G>A
    LMO7-ALK rearrangement
    FGFR2-ERC1 fusion
    HIVEP1-ALK fusion
    EGFR-SEPTIN14 rearrangement
    CCDC6-RET fusion + RET-NRG3 fusion
    SLC8A1-PKDCC-ALK fusion + ALK overexpression
    STARD3NL-MET fusion
    EGFR exon 19 deletion + ATM S1455fs*36 + MYC E62K
    BAIAP2-ROS1 fusion
    MET-UBE2H fusion
    EGFR G719D + EGFR L861Q + CUX1-MET fusion
    PRKCB-ALK fusion
    SND1-BRAF fusion
    EGFR exon 19 deletion + EGFR T790M + EGFR C797S + CTNNB1 exon 3 mutation
    EML4-ALK variant 3 + TP53 mutation
    KEAP1 deletion
    WNK1-ROS1 fusion + ROS1 G2032R
    EGFR mutation + PIK3CA mutation
    KRAS G12D + TP53 deletion
    CD74-ROS1 D2033N fusion
    KRAS G12C + STK11 mutation
    ATM deletion
    KRAS mutation + STK11 mutation
    KEAP1 mutation + MSI-L/dMMR
    SERPINH1 overexpression
    TPM3-NTRK1 fusion + ALK L1196M
    TMB-H
    CD74-ROS1 fusion + MET D1228N + MET amplification
    CLDN18.2 expression
    UPP1 overexpression
    CDH2 overexpression + KRAS wild-type
    EGFR mutation + TTF1 negative
    RBM10 deletion + EGFR mutation
    MTAP deletion + KRAS G12C
    PBRM1 mutation + TMB-L + MSI-L/dMMR
    KRAS mutation + STK11 mutation + AXL expression
    EGFR mutation + RPS6KB1 amplification
    EGFR mutation + ANKRD1 overexpression
    BRAF mutation + TMB-L + MSI-L/dMMR
    EGFR mutation + IDH1 mutation
    KIF5B-RET fusion + TP53 H193R + MYC amplification
    PBRM1 mutation + MSI-L/dMMR
    TRIM33-RET fusion
    BRAF-ZC3H7A fusion
    KLC1-ALK fusion
    EGFR mutation + LANCL2 overexpression
    EGFR mutation + PTEN mutation
    ARID1A mutation + MSI-H
    EGFR mutation + ATM mutation
    HRAS Q61L + NRAS Q61K
    SLC8A1-ALK fusion
    CCDC6-RET fusion
    PBRM1 mutation
    SMARCA4 mutation
    YBX1 overexpression
    ALDH1A1 overexpression
    BLK underexpression
    CDC25C overexpression
    EGFR exon 19 deletion + CCND1 overexpression
    CFTR expression
    EGFR exon 19 deletion + NRAS Q61K
    PTEN deletion
    EGFR mutation + KRAS mutation
    FGFR3 G691R
    FGFR3 S249C
    EGFR-RAD51 fusion
    EGFR mutation + NRAS Q61K
    PD-L1 expression + PVR expression
    EGFR mutation + ROMO1 overexpression
    EGFR mutation + YAP1 overexpression
    EGFR mutation + YES1 overexpression
    ALK positive + YES1 overexpression
    KEAP1 mutation + KRAS mutation
    UHRF1 rs2261988C>A
    GHR-ALK fusion
    ALK-LIMS1 fusion
    NOTCH2-NTRK1 fusion + EGFR L858R
    ALK positive + YAP1 overexpression
    ARF1 rs11541557G>T
    PAPSS1 underexpression
    KIAA1217-RET fusion
    DVL2 rs2074216G>A
    EGFR mutation + BRAF mutation + TP53 mutation
    SPTA1 mutation + KEAP1 mutation
    PTGR1 elevation + HRD
    ERO1A overexpression
    NRG1 rearrangement