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BIOMARKER:
LMNA-NTRK1 fusion
i
Other names:
LMNA, Prelamin-A/C, LMN1, Mandibuloacral dysplasia type A, Limb girdle muscular dystrophy 1B (autosomal dominant), Cardiomyopathy dilated 1A (autosomal dominant), Lamin A/C, FPLD2, LGMD1B, CMT2B1, Renal carcinoma antigen NY-REN-32, Progeria 1 (hutchinson-gilford type), NTRK1, MTC, TRK, TRKA, Neurotrophic tyrosine kinase, receptor, type 1
Associations
(3)
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Trials
C3 | Sensitive
C4 | Sensitive
D | Sensitive
C3 | Resistant
C4 | Resistant
D | Resistant
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Include preclinical:
Drug categories
Tyrosine Kinase Inhibitors
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Breast Cancer
Soft Tissue Sarcoma
larotrectinib
C3
LMNA-NTRK1 fusion
|
Breast Cancer
|
larotrectinib
C4
LMNA-NTRK1 fusion
|
Soft Tissue Sarcoma
|
larotrectinib
ceritinib
D
LMNA-NTRK1 fusion
|
Breast Cancer
|
ceritinib
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