Group by Gene: Include preclinical: Chemotherapy Epigenetics Wnt Signaling Inhibitors DNA CD Protein Inhibitors Immune Checkpoint Inhibitors Immunotherapy Cyclin Dependent Kinase Inhibitors Serine-Threonine Kinase Inhibitors MDM2/MDMX Other PI3 Kinase Inhibitors PARP Inhibitors FGF Tyrosine Kinase Inhibitors | XPO1 inhibitor selinexor | CDK4 inhibitor, CDK6 inhibitor palbociclib | Alkylating agent, DNA inhibitor trabectedin | PD1 inhibitor pembrolizumab | RAIN-32 | MDM2 inhibitor APG-115 | MK-8242 | HDM201 | MDM2-p53 antagonist BI 907828 | LSD1 inhibitor SP2577 | PIK3CA inhibitor, PI3Kδ inhibitor copanlisib | β-catenin inhibitor, CBP inhibitor, Microtubule inhibitor eribulin mesylate | PARP inhibitor PARP inhibitor | FGFR2 inhibitor, FGFR inhibitor, FGFR1 inhibitor, FGFR3 inhibitor, FGFR4 inhibitor, MDM2 inhibitor erdafitinib + RG7388 | FGFR2 inhibitor, FGFR inhibitor, FGFR1 inhibitor, FGFR3 inhibitor, FGFR4 inhibitor erdafitinib | β-catenin inhibitor, Microtubule stabilizer, Tubulin polymerization promoter, CBP inhibitor, Microtubule inhibitor docetaxel + eribulin mesylate | HDAC inhibitor romidepsin |
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No biomarker | |||||||||||||||||
CALB1 deletion | |||||||||||||||||
CALB1 underexpression | |||||||||||||||||
MDM2 amplification | |||||||||||||||||
GRM1 overexpression | |||||||||||||||||
MDM2 overexpression | |||||||||||||||||
TP53 wild-type | |||||||||||||||||
PIK3CA mutation | |||||||||||||||||
CDK4 amplification | |||||||||||||||||
RB1 expression | |||||||||||||||||
FUS-DDIT3 translocation | |||||||||||||||||
MCM4 overexpression | |||||||||||||||||
MDM2 amplification + TP53 wild-type | |||||||||||||||||
FGFR1 overexpression | |||||||||||||||||
FGFR4 overexpression | |||||||||||||||||
MDM2 amplification + CDK4 amplification | |||||||||||||||||
PIK3CA mutation + TERT promoter mutation |