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BIOMARKER:
KRAS G12V
i
Other names:
KRAS, KRAS1, KRAS2, Kirsten rat sarcoma viral oncogene homolog
Associations
(36)
News
Trials
B | Sensitive
C2 | Sensitive
C3 | Sensitive
C4 | Sensitive
D | Sensitive
B | Resistant
C2 | Resistant
C3 | Resistant
C4 | Resistant
D | Resistant
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Include preclinical:
Drug categories
EGFR
Tyrosine Kinase Inhibitors
Serine-Threonine Kinase Inhibitors
Threonine-Tyrosine Kinase Inhibitors
Immunotherapy
CD Protein Inhibitors
Immune Checkpoint Inhibitors
Kinase Inhibitors
Other
PI3 Kinase Inhibitors
RAS
Chemotherapy
DNA
BCL Inhibitors
Cyclin Dependent Kinase Inhibitors
Epigenetics
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Colorectal Cancer
Non Small Cell Lung Cancer
Solid Tumor
Pancreatic Ductal Adenocarcinoma
Ovarian Cancer
Ovarian Serous Adenocarcinoma
Hepatocellular Cancer
Spindle Cell Sarcoma
Lung Non-Squamous Non-Small Cell Cancer
Pancreatic Cancer
Lung Adenocarcinoma
Colon Cancer
VS-6766 + VS-6063
C2
KRAS G12V
|
Non Small Cell Lung Cancer
|
VS-6766 + VS-6063
C2
KRAS G12V
|
Ovarian Serous Adenocarcinoma
|
VS-6766 + VS-6063
C2
KRAS G12V
|
Ovarian Cancer
|
VS-6766 + VS-6063
panitumumab
B
KRAS G12V
|
Colorectal Cancer
|
panitumumab
bevacizumab
C3
KRAS G12V
|
Colorectal Cancer
|
bevacizumab
AFNT-211
C2
KRAS G12V
|
Solid Tumor
|
AFNT-211
selumetinib
D
KRAS G12V
|
Colorectal Cancer
|
selumetinib
C3
KRAS G12V
|
Non Small Cell Lung Cancer
|
selumetinib
BAL3833
C3
KRAS G12V
|
Spindle Cell Sarcoma
|
BAL3833
sorafenib + BAY86-9766
C3
KRAS G12V
|
Hepatocellular Cancer
|
sorafenib + BAY86-9766
VS-6766
C3
KRAS G12V
|
Non Small Cell Lung Cancer
|
VS-6766
RGX-202
C3
KRAS G12V
|
Colorectal Cancer
|
RGX-202
bevacizumab + PCM-075
C3
KRAS G12V
|
Colorectal Cancer
|
bevacizumab + PCM-075
nivolumab + rigosertib
C3
KRAS G12V
|
Non Small Cell Lung Cancer
|
nivolumab + rigosertib
anlotinib
C4
KRAS G12V
|
Pancreatic Ductal Adenocarcinoma
|
anlotinib
erlotinib
C3
KRAS G12V
|
Non Small Cell Lung Cancer
|
erlotinib
ME-522
D
KRAS G12V
|
Colorectal Cancer
|
ME-522
pembrolizumab
D
KRAS G12V
|
Non Small Cell Lung Cancer
|
pembrolizumab
BMF-219
D
KRAS G12V
|
Pancreatic Cancer
|
BMF-219
gemcitabine + paclitaxel
C3
KRAS G12V
|
Pancreatic Ductal Adenocarcinoma
|
gemcitabine + paclitaxel
osimertinib
C4
KRAS G12V
|
Lung Adenocarcinoma
|
osimertinib
QTX3034
D
KRAS G12V
|
Solid Tumor
|
QTX3034
AZ 628
D
KRAS G12V
|
Colorectal Cancer
|
AZ 628
panitumumab + VS-6766
D
KRAS G12V
|
Colorectal Cancer
|
panitumumab + VS-6766
selumetinib + AZ 628
D
KRAS G12V
|
Colorectal Cancer
|
selumetinib + AZ 628
BI-2493
D
KRAS G12V
|
Solid Tumor
|
BI-2493
palbociclib
D
KRAS G12V
|
Non Small Cell Lung Cancer
|
palbociclib
JQ-1
D
KRAS G12V
|
Non Small Cell Lung Cancer
|
JQ-1
sunitinib
D
KRAS G12V
|
Colorectal Cancer
|
sunitinib
cetuximab
B
KRAS G12V
|
Colorectal Cancer
|
cetuximab
trametinib
D
KRAS G12V
|
Ovarian Cancer
|
trametinib
Immunotherapy
C3
KRAS G12V
|
Non Small Cell Lung Cancer
|
Immunotherapy
C3
KRAS G12V
|
Lung Non-Squamous Non-Small Cell Cancer
|
Immunotherapy
CDK9 inhibitor
D
KRAS G12V
|
Colon Cancer
|
CDK9 inhibitor
PD-L1 inhibitor
C3
KRAS G12V
|
Non Small Cell Lung Cancer
|
PD-L1 inhibitor
FOLFOX
C3
KRAS G12V
|
Colorectal Cancer
|
FOLFOX
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