^
    BIOMARKER:

    KMT2A rearrangement

    i
    Other names: KMT2A, Lysine Methyltransferase 2A, Histone-Lysine N-Methyltransferase 2A, CXXC7, TRX1, Myeloid/Lymphoid Or Mixed-Lineage Leukemia (Trithorax Homolog, Drosophila), Lysine (K)-Specific Methyltransferase 2A, CXXC-Type Zinc Finger Protein 7, Lysine N-Methyltransferase 2A, Zinc Finger Protein HRX, Trithorax-Like Protein, HTRX1, MLL1A, MLL1, MLL, Myeloid/Lymphoid Or Mixed-Lineage Leukemia (Trithorax (Drosophila) Homolog), Myeloid/Lymphoid Or Mixed-Lineage Leukemia Protein 1, Myeloid/Lymphoid Or Mixed




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    Include preclinical:
    Acute Myelogenous Leukemia
    Acute Lymphocytic Leukemia
    B Acute Lymphoblastic Leukemia
    Childhood B Acute Lymphoblastic Leukemia
    CEP-701
    SNDX-5613
    blinatumomab
    bortezomib + vorinostat + mitoxantrone
    azacitidine
    venetoclax + SNDX-5613
    KO-539
    gemtuzumab ozogamicin
    venetoclax
    venetoclax + sunitinib + I-BET151
    DS-1594
    PRT2527
    SNDX-5613 + ORY-1001
    FLT3 inhibitor + gilteritinib
    Menin-MLL inhibitor