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BIOMARKER:
HRAS mutation
i
Other names:
HRAS, HRAS1, Harvey rat sarcoma viral oncogene homolog
Associations
(11)
News
Trials
B | Sensitive
C2 | Sensitive
C3 | Sensitive
D | Sensitive
B | Resistant
C2 | Resistant
C3 | Resistant
D | Resistant
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Include preclinical:
Drug categories
Chemokine
EGFR
Tyrosine Kinase Inhibitors
Threonine-Tyrosine Kinase Inhibitors
Serine-Threonine Kinase Inhibitors
Other
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Squamous Cell Carcinoma of Head and Neck
Urothelial Cancer
Salivary Gland Cancer
Melanoma
Rhabdomyosarcoma
Endometrial Cancer
Bladder Cancer
Solid Tumor
tipifarnib
B
HRAS mutation
|
Squamous Cell Carcinoma of Head and Neck
|
tipifarnib
C2
HRAS mutation
|
Urothelial Cancer
|
tipifarnib
C3
HRAS mutation
|
Salivary Gland Cancer
|
tipifarnib
D
HRAS mutation
|
Rhabdomyosarcoma
|
tipifarnib
cobimetinib + RG6185
C3
HRAS mutation
|
Melanoma
|
cobimetinib + RG6185
selumetinib
C3
HRAS mutation
|
Solid Tumor
|
selumetinib
cetuximab
C3
HRAS mutation
|
Squamous Cell Carcinoma of Head and Neck
|
cetuximab
AZ 628
D
HRAS mutation
|
Endometrial Cancer
|
AZ 628
PD-0325901
D
HRAS mutation
|
Endometrial Cancer
|
PD-0325901
FL118
D
HRAS mutation
|
Bladder Cancer
|
FL118
trametinib + tipifarnib
D
HRAS mutation
|
Rhabdomyosarcoma
|
trametinib + tipifarnib
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