^
    DRUG CLASS:

    HER2 inhibitor





    Show legend
    Group by Gene:
    Include preclinical:

    trastuzumab
    HER2 inhibitor
    trastuzumab + tucatinib
    trastuzumab-pkrb
    trastuzumab-dttb
    trastuzumab-anns
    trastuzumab-dkst
    trastuzumab-qyyp
    Zercepac (trastuzumab biosimilar)
    ZW25
    tucatinib
    margetuximab
    KN026
    LZM-005
    trastuzumab + LZM-005
    TX05 (trastuzumab biosimilar)
    Hervelous (trastuzumab biosimilar)
    		0
    HER2 inhibitor
    Her-VAXX
    DF1001
    AST-301
    inetetamab
    DZD1516
    ZN-A-1041
    IAH0968
    MP0274
    EG12014 (trastuzumab biosimilar)
    Hercease (trastuzumab biosimilar)
    HERtiCAD (trastuzumab biosimilar)
    ACE1702
    trastuzumab / hyaluronidase-oysk
    trastuzumab-IFN-β mutein
    JBJ-08–178–01
    trastuzumab
    AB-201
    VRN101099
    trastuzumab + pertuzumab
    pertuzumab / trastuzumab / hyaluronidase-zzxf
    		1
    HER2 inhibitor, HER2 dimerization inhibitor
    pertuzumab + trastuzumab-pkrb
    pertuzumab + Zercepac (trastuzumab biosimilar)
    pertuzumab + inetetamab
    pertuzumab + trastuzumab-dttb
    2
    HER2 inhibitor, HER3 inhibitor
    MCLA-128
    trastuzumab + MCLA-128
    trastuzumab + abemaciclib
    palbociclib + tucatinib
    		3
    HER2 inhibitor, CDK4 inhibitor, CDK6 inhibitor
    palbociclib + ZW25
    trastuzumab + palbociclib
    tucatinib + PRT3645
    abemaciclib + tucatinib
    4
    HER2 inhibitor, HER4 inhibitor, pan-EGFR inhibitor
    poziotinib
    pembrolizumab + trastuzumab
    pembrolizumab + margetuximab
    nivolumab + trastuzumab
    		5
    HER2 inhibitor, PD1 inhibitor
    trastuzumab + camrelizumab
    trastuzumab + tislelizumab
    tislelizumab + ZW25
    margetuximab + retifanlimab-dlwr
    camrelizumab + inetetamab
    trastuzumab + ramucirumab
    		6
    VEGFR-2 inhibitor, HER2 inhibitor
    trastuzumab + ramucirumab + tucatinib
    trastuzumab + rivoceranib
    7
    HER2 inhibitor, γδ TCR modulator
    Undisclosed allogeneic Vγ9Vδ2 HER2-TAC T
    8
    HER2 inhibitor, mTOR inhibitor
    trastuzumab + everolimus
    sirolimus + inetetamab
    9
    PIK3CA inhibitor, HER2 inhibitor, HER2 dimerization inhibitor
    trastuzumab + pertuzumab + alpelisib
    trastuzumab + lapatinib
    lapatinib
    BDTX-189
    MET306
    		10
    HER2 inhibitor, EGFR inhibitor
    mobocertinib
    trastuzumab + osimertinib + necitumumab
    trastuzumab + erlotinib
    trastuzumab + S-222611
    TAS2940
    Bay846
    11
    VEGF-A inhibitor, HER2 inhibitor
    bevacizumab + trastuzumab
    12
    VEGFR-2 inhibitor, HER2 inhibitor, CD47 inhibitor
    trastuzumab + ramucirumab + ALX148
    trastuzumab + avelumab
    		13
    PD-L1 inhibitor, HER2 inhibitor
    trastuzumab + atezolizumab
    trastuzumab + durvalumab
    D3L-001
    		14
    HER2 inhibitor, CD47 inhibitor
    trastuzumab + GS-4721
    IMM2902
    15
    PIK3CA inhibitor, HER2 inhibitor
    trastuzumab + alpelisib
    16
    PIK3CA inhibitor, HER2 inhibitor, HER3 inhibitor
    trastuzumab + alpelisib + LJM-716
    17
    AXL inhibitor, HER2 inhibitor
    trastuzumab + TP-0903
    afatinib
    pyrotinib
    neratinib
    trastuzumab + neratinib
    osimertinib + afatinib
    trastuzumab + pyrotinib
    		18
    HER2 inhibitor, HER4 inhibitor, EGFR inhibitor
    ASLAN001
    cetuximab + afatinib
    pyrotinib + inetetamab
    lapatinib + pyrotinib
    afatinib + pyrotinib
    lapatinib + neratinib
    afatinib + gefitinib
    19
    Aromatase inhibitor, HER2 inhibitor, EGFR inhibitor
    Aromatase inhibitor + trastuzumab + lapatinib
    20
    Aromatase inhibitor, HER2 inhibitor
    HER2 inhibitor + Aromatase inhibitor
    21
    HER2 inhibitor, Erythropoiesis stimulating agent
    HER2 inhibitor + Erythropoiesis stimulating agent
    22
    PD-L1 inhibitor, HER2 inhibitor, CTLA4 inhibitor
    KN046 + KN026
    23
    HER2 inhibitor, HER4 inhibitor, pan-EGFR inhibitor, HER2-targeted CAR-T immunotherapy
    HER2-targeted CAR-T immunotherapy + poziotinib
    24
    VEGF-A inhibitor, HER2 inhibitor, HER4 inhibitor, EGFR inhibitor
    bevacizumab + afatinib
    bevacizumab + pyrotinib
    25
    CD137 agonist, HER2 inhibitor
    PRS-343
    ABL105
    26
    HER2 inhibitor, PI3K inhibitor, mTOR inhibitor, mTORC1 inhibitor, mTORC2 inhibitor
    PF-05212384 + trastuzumab-pkrb
    pyrotinib + dalpiciclib
    		27
    HER2 inhibitor, HER4 inhibitor, CDK4 inhibitor, EGFR inhibitor, CDK6 inhibitor
    trastuzumab + palbociclib + pyrotinib
    palbociclib + neratinib
    rivoceranib + pyrotinib
    		28
    VEGFR-2 inhibitor, HER2 inhibitor, HER4 inhibitor, EGFR inhibitor
    afatinib + rivoceranib
    afatinib + ramucirumab
    29
    HER2 inhibitor, EGFR inhibitor, BTK inhibitor
    DZD9008
    30
    Aromatase inhibitor, HER2 inhibitor, HER4 inhibitor, EGFR inhibitor
    pyrotinib + letrozole
    31
    Protein synthesis inhibitor, HER2 inhibitor
    MT-5111
    32
    HER2 inhibitor, HER4 inhibitor, HER2-targeted antibody-drug conjugate, EGFR inhibitor, Microtubule inhibitor
    neratinib + ado-trastuzumab emtansine
    ado-trastuzumab emtansine + pyrotinib
    33
    HER2 inhibitor, HER4 inhibitor, EGFR inhibitor, CD13 inhibitor
    afatinib + DFP-14323
    34
    HER2 inhibitor, PD1 inhibitor, LAG-3 inhibitor
    margetuximab + MGD013
    35
    HER2 inhibitor, HER4 inhibitor, PD1 inhibitor, EGFR inhibitor
    pembrolizumab + afatinib
    camrelizumab + pyrotinib
    36
    Macrophage stimulant, HER2 inhibitor
    CT-0508
    37
    HER2 inhibitor, HER4 inhibitor, EGFR inhibitor, Multi-tyrosine kinase inhibitor
    afatinib + anlotinib
    38
    PD-L1 inhibitor, HER2 inhibitor, HER4 inhibitor, EGFR inhibitor
    atezolizumab + afatinib
    39
    PD-L1 inhibitor, HER2 inhibitor, HER2 dimerization inhibitor
    trastuzumab + atezolizumab + pertuzumab
    40
    VEGFR inhibitor, HER2 inhibitor, EGFR inhibitor, EphB4 inhibitor
    KD019
    41
    HER2 inhibitor, PI3K inhibitor
    trastuzumab + MEN1611
    trastuzumab + SAR245408
    42
    Topoisomerase II inhibitor, HER2 inhibitor, HER2-targeted antibody-drug conjugate
    trastuzumab + MM-302
    43
    HER2 inhibitor, HER4 inhibitor, MEK inhibitor, EGFR inhibitor
    afatinib + selumetinib
    trametinib + neratinib
    44
    PIK3CA inhibitor, HER2 inhibitor, PI3Kδ inhibitor
    trastuzumab + copanlisib
    45
    AKT3 inhibitor, HER2 inhibitor, AKT1 inhibitor, AKT inhibitor, p70S6K inhibitor
    trastuzumab + DIACC3010
    46
    HER2 inhibitor, TLR7 agonist, TLR8 agonist
    BDC-1001
    47
    HER2 inhibitor, HER4 inhibitor, mTOR inhibitor, EGFR inhibitor
    neratinib + temsirolimus
    everolimus + neratinib
    48
    HER2 inhibitor, CD20 inhibitor
    trastuzumab + TQB2303 (rituximab biosimilar)
    49
    HER2 inhibitor, PD1 inhibitor, TLR7 agonist, TLR8 agonist
    nivolumab + BDC-1001
    50
    VEGF-A inhibitor, HER2 inhibitor, EGFR inhibitor
    bevacizumab + mobocertinib
    51
    HER2 inhibitor, EGFR inhibitor, HER2 exon 20 mutation inhibitor
    BAY 2927088
    52
    FGFR inhibitor, VEGFR inhibitor, RET inhibitor, HER2 inhibitor, HER4 inhibitor, PD1 inhibitor, EGFR inhibitor, c-KIT inhibitor, PDGFR α antagonist
    pembrolizumab + lenvatinib + pyrotinib
    53
    HER2 inhibitor, CTLA4 inhibitor
    trastuzumab + tremelimumab
    54
    HER2 inhibitor, DNA synthesis inhibitor, EGFR inhibitor
    trastuzumab + erlotinib + gemcitabine
    55
    HER2 inhibitor, HER4 inhibitor, ROS1 inhibitor, ALK inhibitor, EGFR inhibitor
    afatinib + lorlatinib
    56
    HER2 inhibitor, HER4 inhibitor, PD1 inhibitor, EGFR inhibitor, Multi-tyrosine kinase inhibitor
    nivolumab + anlotinib + pyrotinib
    57
    HER2 inhibitor, ALK inhibitor
    trastuzumab + crizotinib
    ado-trastuzumab emtansine + tucatinib
    		58
    HER2 inhibitor, HER2-targeted antibody-drug conjugate, Microtubule inhibitor
    tucatinib + disitamab vedotin
    ado-trastuzumab emtansine + AST-301
    59
    HER2 inhibitor, JAK1 inhibitor, JAK2 inhibitor
    trastuzumab + ruxolitinib
    60
    HER2 inhibitor, CDK4 inhibitor, CDK6 inhibitor, HER2 dimerization inhibitor
    trastuzumab + palbociclib + pertuzumab
    palbociclib + pertuzumab + abemaciclib + ribociclib + trastuzumab / hyaluronidase-oysk
    61
    HER2 inhibitor, HER4 inhibitor, JAK1 inhibitor, EGFR inhibitor, JAK2 inhibitor
    afatinib + ruxolitinib
    62
    HER2 inhibitor, PD1 inhibitor, HER2 dimerization inhibitor
    pembrolizumab + pertuzumab + trastuzumab-qyyp
    63
    HER2 inhibitor, HER2-targeted antibody-drug conjugate, Microtubule inhibitor, HER2 dimerization inhibitor
    trastuzumab + pertuzumab + ado-trastuzumab emtansine
    64
    HER2 inhibitor, HER4 inhibitor, EGFR inhibitor, HER2 dimerization inhibitor
    afatinib + pertuzumab
    65
    HER2 inhibitor, PD1 inhibitor, EGFR inhibitor
    nivolumab + lapatinib
    66
    HER2 inhibitor, HER2-targeted antibody-drug conjugate, EGFR inhibitor, Microtubule inhibitor
    lapatinib + ado-trastuzumab emtansine
    ado-trastuzumab emtansine + mobocertinib
    67
    Bcr-abl tyrosine kinase inhibitor, HER2 inhibitor, EGFR inhibitor, Src kinase inhibitor, c-KIT inhibitor, PDGFR β antagonist, EphA2 receptor antagonist
    dasatinib + lapatinib
    68
    HER2 inhibitor, HER4 inhibitor, PI3K inhibitor, EGFR inhibitor
    AN2025 + ASLAN001
    69
    KRAS G12D inhibitor, HER2 inhibitor, HER4 inhibitor, EGFR inhibitor
    afatinib + MRTX1133
    70
    HER2 inhibitor, HER4 inhibitor, PTPN11 inhibitor, EGFR inhibitor
    afatinib + SHP099
    71
    HER2 inhibitor, HER4 inhibitor, PI3K inhibitor, mTOR inhibitor, EGFR inhibitor, mTORC1 inhibitor, mTORC2 inhibitor
    neratinib + PF-05212384
    72
    HER2 inhibitor, HER4 inhibitor, HER2-targeted antibody-drug conjugate, EGFR inhibitor, Topoisomerase I inhibitor
    neratinib + fam-trastuzumab deruxtecan-nxki
    73
    HER2 inhibitor, CD47 inhibitor, HER2 dimerization inhibitor
    pertuzumab + D3L-001
    74
    c-MET inhibitor, HER2 inhibitor, EGFR inhibitor
    amivantamab-vmjw + mobocertinib
    75
    HER2 inhibitor, HER4 inhibitor, EGFR inhibitor, PARP inhibitor
    olaparib + neratinib
    neratinib + niraparib
    76
    HER2 inhibitor, EGFR inhibitor, Multi-tyrosine kinase inhibitor
    AEE788
    77
    HER2 inhibitor, WEE1 inhibitor
    trastuzumab + ZN-c3
    78
    HER2 inhibitor, NRF2 inhibitor
    trastuzumab + brusatol
    79
    TNFα inhibitor, HER2 inhibitor, HER4 inhibitor, NF-κB inhibitor, EGFR inhibitor
    afatinib + omtriptolide
    80
    HER2 inhibitor, PI3Kα H1047R mutation inhibitor
    tucatinib + OKI-219
    81
    Retinoid X receptor agonist, HER2 inhibitor, HER4 inhibitor, EGFR inhibitor
    neratinib + IRX4204
    82
    Retinoid X receptor agonist, HER2 inhibitor
    tucatinib + IRX4204
    trastuzumab + IRX4204
    83
    HER2 inhibitor, CDK4 inhibitor, EGFR inhibitor, CDK6 inhibitor
    palbociclib + lapatinib
    84
    PD-L1 inhibitor, HER2 inhibitor, PD1 inhibitor
    trastuzumab + BMS-202
    85
    HER2 inhibitor, HER4 inhibitor, Androgen receptor inhibitor, EGFR inhibitor
    afatinib + enzalutamide capsule
    86
    PIK3CA inhibitor, HER2 inhibitor, HER4 inhibitor, EGFR inhibitor
    alpelisib + pyrotinib
    87
    HER2 inhibitor, HER2-targeted antibody-drug conjugate, Topoisomerase I inhibitor
    fam-trastuzumab deruxtecan-nxki + tucatinib
    88
    c-MET inhibitor, HER2 inhibitor
    trastuzumab + savolitinib
    89
    HER2 inhibitor, NK cell stimulant
    trastuzumab + CYNK-101
    90
    HER2 inhibitor, Cytotoxic T lymphocyte stimulant, CD3 agonist
    SAR446309
    91
    T-cell stimulant, HER2 inhibitor, CD3 agonist, CD28 agonist
    SAR443216
    92
    HER2 inhibitor, KRAS G12C inhibitor, HER4 inhibitor, EGFR inhibitor
    afatinib + sotorasib
    93
    HER2 inhibitor, EGFR inhibitor, Bcl2 inhibitor, Bcl-xL inhibitor
    lapatinib + APG-1252
    94
    HER2 inhibitor, EGFR C797S inhibitor
    ER121
    95
    HER2 inhibitor, HER4 inhibitor, pan-EGFR inhibitor, EGFR inhibitor
    lapatinib + poziotinib
    96
    Bcr-abl tyrosine kinase inhibitor, HER2 inhibitor, HER4 inhibitor, EGFR inhibitor, Src kinase inhibitor, c-KIT inhibitor, PDGFR β antagonist, EphA2 receptor antagonist
    dasatinib + neratinib
    97
    PIK3CA inhibitor, HER2 inhibitor, HER4 inhibitor, EGFR inhibitor, PI3Kδ inhibitor
    neratinib + copanlisib
    98
    HER2 inhibitor, α radiation emission
    BAY2701439
    99
    HER2 inhibitor, BRAF inhibitor, EGFR inhibitor
    lapatinib + PLX4720
    100
    HER2 inhibitor, PARP inhibitor
    trastuzumab + talazoparib
    101
    Estrogen receptor antagonist, HER2 inhibitor, Selective estrogen receptor degrader
    HER2 inhibitor + OP-1250
    No biomarker
    HER-2 positive
    HER-2 overexpression
    HER-2 amplification
    HER-2 mutation
    HER-2 expression
    HER-2 exon 20 insertion
    HER-2 S310F
    HER-2 positive + HER-2 amplification
    HER-2 A775_G776insYVMA
    HER-2 L755S
    HER-2 exon 20 mutation
    HER-2 E395K
    HER-2 Q57R
    HER-2 D769Y
    HER-2 G778_P780dup
    HER-2 negative
    HER-2 underexpression
    HER-2 V777L
    HER-2 L755_T759del
    HER-2 I655V
    HER-2 expression + HER-2 amplification
    HER-2 R896G
    HER-2 elevation
    HER-2 amplification + HER-2 L755S
    HER-2 S310F + HER-2 amplification
    HER-2 amplification + HER-2 mutation
    HER-2 YVMA
    HER-2 A1170P
    HER-2 Y772_A775dup
    HER-2 mutation + HER-2 positive
    HER-2 overexpression + HER-2 amplification
    HER-2 G778_S779insCPG
    HER-2 G780_P781dupGSP
    HER-2 778insGSP
    HER-2 fusion
    HER-2 amplification + HER-2 R157W
    HER-2 V659D
    HER-2 exon 20 G776delinsVC
    HER-2 G776L
    HER-2 L755P
    HER-2 S335C
    HER-2 V842I
    HER-2 R896C
    HER-2 D769H
    HER-2 mutation + HER-2 T798I
    HER-2 G660D + HER-2 S310F
    HER-2 exon 17 mutation
    HER-2 V658E
    HER-2 G766V
    HER-2 exon 19 deletion
    HER-2 C634R
    HER-2 exon 19 mutation
    HER-2 V773A
    HER-2 T862A + HER-2 L755S
    HER-2 H878Y
    HER-2 G776insV_C
    HER-2 G776insV_G
    HER-2 expression + HER-2 D769H
    HER-2 expression + HER-2 L869R
    HER-2 1899‐1G>A
    HER-2 K753E
    HER-2 L768S
    HER-2 K676R
    HER-2 Q680R
    HER-2 R647K
    HER-2 V773L
    HER-2 T798I
    HER-2 R678Q
    HER-2 755_759del
    HER-2 G309A
    HER-2 P780ins
    HER-2 N857S
    HER-2 L869R
    HER-2 T862A
    HER-2 S310Y
    HER-2 exon 20G776>VC insertion
    HER-2 exon 20 YVMA insertion
    HER-2 G776S
    p95HER2 mutation
    EGFR mutation
    EGFR expression
    EGFR amplification
    EGFR exon 20 insertion
    EGFR exon 19 deletion
    EGFR L858R
    EGFR G719X
    EGFR L858R + EGFR T790M
    EGFR L861Q
    EGFR exon 19 deletion + EGFR T790M
    EGFR R1052K
    EGFR exon 18 mutation
    EGFR S768I
    EGFR T790M
    EGFR L861Q + EGFR G719X
    EGFR L833V + EGFR H835L
    EGFR G719X + EGFR S768I
    EGFR N771delinsKG
    EGFR A767_V769dup
    EGFR E709_T710delinsD
    EGFR L747P
    EGFR G719A + EGFR R776C
    EGFR L861R
    EGFR E690K
    EGFR overexpression
    EGFR exon 18-25 duplication
    EGFR R776H + EGFR L861Q
    EGFR G719X + EGFR E709F
    EGFR L858R + EGFR S765I
    EGFR D770_N771insSVD
    EGFR L858R + EGFR S768I
    EGFR R776C + EGFR L861Q
    EGFR exon 19 deletion + EGFR L747S
    EGFR exon 19 deletion + EGFR S768I
    EGFR L833V
    EGFR H835L
    EGFR G2607A
    EGFR delE709_T710insD
    EGFR exon 18 deletion
    EGFR exon 19 insertion
    EGFR T854A
    EGFR exon 20 insertion + EGFR G719X + EGFR L858R
    EGFR L718Q
    EGFR negative
    EGFR G724S + EGFR R776H
    EGFR K745_E746insIPVAIK
    EGFR exon 19 deletion + EGFR K754E
    EGFR G719S + EGFR S768I
    EGFR L747S
    EGFR A763_Y764insFQEA
    EGFR E746_A750del
    EGFR exon 19 deletion + EGFR G724S
    EGFR exon 20 mutation
    EGFR C797S
    EGFR exon 19 mutation
    EGFR exon 21 mutation
    EGFR exon 19 deletion + EGFR G724S + EGFR T790M
    EGFR T263P
    EGFR G724S
    EGFR mutation + EGFR T790M
    EGFR L858R + EGFR L718Q
    EGFR L858R + EGFR L747V
    EGFR G719C + EGFR E709V
    EGFR exon 18 mutation + EGFR exon 21 mutation
    EGFR M277E
    EGFR G719A + EGFR T790M
    EGFR G719C
    EGFR G719A
    EGFR C797S + EGFR exon 20 insertion
    EGFR G729A + EGFR L858R
    EGFR L858R + EGFR M766Q
    EGFRvIII mutation
    EGFR A289V
    EGFR exon 20 insertion + EGFR T790M
    EGFR T790M + EGFR L833V + EGFR H835L
    EGFR T790M + EGFR S768I + EGFR L858R
    EGFR exon 19 deletion + EGFR L861Q
    EGFR A767dupASV
    EGFR S768dupSVD
    EGFR L833F + EGFR L861Q
    HR positive
    HR negative
    ER positive + PGR positive
    HER-2 amplification + RAS wild-type + BRAF wild-type
    BRAF wild-type + HER-2 positive
    PIK3CA mutation
    PIK3CA E542K
    PIK3CA H1047
    PIK3CA G1049R
    PIK3CA E545
    PIK3CA Q546
    PIK3CA M1043I
    PIK3CA amplification
    PIK3CA H1047L
    PIK3CA E542Q
    PIK3CA wild-type
    PIK3CA H1047R
    PIK3CA N345K
    PIK3CA E453K
    PIK3CA E545K
    PIK3CA mutation + HR negative
    ER positive
    ER negative
    ERBB3-L
    ERBB3 mutation
    ERBB3 amplification
    ERBB3 G284R
    ERBB3 V659E
    ERBB3 R103G
    ERBB3 V104L
    ERBB3 V104L + HER-2 negative
    ERBB3 amplification + ERBB3 mutation
    ERBB3 V104M
    ERBB3 E952Q
    ERBB3 expression
    NRG1 fusion
    NRG1 overexpression
    NRG1 mutation
    NRG1 fusion
    NRG1 rearrangement
    HER-2 positive + PD-L1 expression
    HER-2 amplification + PD-L1 expression
    PD-L1 expression + HER-2 overexpression
    PD-L1 expression
    FCGR3A 158V
    FCGR3A 158F
    HR positive + HER-2 positive
    PD-L1 overexpression
    HR positive + HER-2 amplification
    HR positive + HER-2 mutation
    HER-2 amplification + ER positive + PGR negative
    PD-L1 elevation
    PTEN overexpression
    HER-2 expression + TMB-H
    PTEN expression
    TMB-H + HER-2 positive
    HER-2 elevation + TMB-L
    EGFR amplification + ERBB2 amplification
    EGFR exon 19 deletion + HER-2 amplification
    HER-2 amplification + EGFR-ZNF880 fusion + EGFR E114K
    EGFR exon 19 deletion + EGFR T790M + EGFR C797S + HER-2 amplification
    EGFR expression + HER-2 expression
    EGFR overexpression + HER-2 overexpression
    HER-2 V777L + EGFR L858R
    PTEN deletion
    PTEN rs701848
    RAS wild-type + HER-2 positive
    HR-positive + PIK3CA wild-type
    ERBB4 G668V
    PIK3CA mutation + HR positive
    ABCB1 G2677T
    ABCB1 C1236T
    ABCB1 C3435T
    ERBB4 mutation
    ABCB1 G1236T + ABCB1 G2677T
    ERBB4 G1109C
    ERBB4 expression
    ABCB1 overexpression
    ATP1B1-NRG1 fusion
    CD74-NRG1 fusion
    ACTA2 elevation
    ADRB2 overexpression
    CDKN2A negative
    MYBL2 overexpression
    PD-1 overexpression
    HER-2 overexpression + KRAS wild-type
    HER-2 amplification + KRAS wild-type
    HER-2 amplification + KRAS exon 2 wild-type
    KRAS mutation + HER-2 positive
    CDKN2A deletion
    ACTA2 overexpression
    HER-2 amplification + KRAS G12D
    MUC16 mutation
    YAP1 overexpression
    KMT2B mutation
    KIR3DL2 mutation
    RAS wild-type + BRAF wild-type + HER-2 positive
    MET N375S
    APP-NRG1 fusion
    SLC3A2-NRG1 fusion
    FGFR1 amplification
    PIK3CA H1047R + HER-2 amplification
    POMK‐NRG1 fusion + KRAS G12D
    POMK-NRG1 fusion + KRAS mutation
    PIK3CA mutation + HER-2 positive
    MET amplification
    HER-2 V777L + PIK3CA H1047R
    AXL-L
    EGFR exon 19 deletion + PD-L1 overexpression
    EGFR L858R + ALK rearrangement
    KRAS mutation
    HER-2 mutation + CDK6 mutation
    MAF1 overexpression
    miR-21 overexpression
    MLL2 mutation
    NF1 mutation + HER-2 positive
    ERBB4 mutation + HER-2 positive
    HER-2 mutation + TP53 wild-type
    PIK3C3 mutation + HER-2 positive
    PIK3R1 mutation + HER-2 positive
    TGFBI promoter hypermethylation
    IRF8 overexpression + ER negative
    POLE E790Q + ERBB2 amplification + TMB-H
    PIK3R1 EY451delinsD
    ALK rearrangement + ALK I1171N + ALK V1180L + BRCA2 F2801fs
    MSI-H/dMMR + TMB-H
    SDC4-NRG1 fusion
    MCM10 overexpression
    HER-2 amplification + MET amplification
    KIF5B-EGFR fusion
    ER negative + HER-2 positive + PGR positive + PIK3CA mutation
    GRB7 positive
    CD74-NRG1 fusion + EGFR mutation + HER-2 mutation
    WBP2 overexpression
    CD8-H
    PGR positive
    TP53 mutation
    EGF overexpression
    EGFR exon 20 insertion + TP53 G244A + SPTA1 mutation
    POLE mutation + PD-L1 negative + TMB-H
    ERBB3 R135C + TMB-H
    VHL mutation
    AKT2 expression
    ANXA6 underexpression
    IL18 elevation
    CDK12 amplification
    NPTN-NRG1 fusion
    ER positive + HER-2 D769H + HER-2 V777L
    TNFA elevation
    IL6 elevation
    BARD1 T351T
    EGFR L858R + EGFR E709X + CTNNB1 mutation
    ERBB3 mutation + HER-2 amplification
    VEGFA overexpression
    TET1 mutation
    KRAS G12C
    MET overexpression + HER-2 overexpression
    KRAS G12D
    HER-2 positive + TP53 mutation
    EGFR mutation + PD-L1 overexpression
    AXL overexpression
    MET expression + HER-2 expression
    AXL underexpression
    ERBB3 mutation + HER-2 mutation
    Rbsig overexpression
    Low PLR
    MAF1 expression
    EGFR L861Q + TP53 mutation
    EGFR S768I + TP53 mutation
    DLD overexpression
    CD47 positive + HER-2 positive
    CD47 positive
    TSC2 C1450G
    IGF2 overexpression
    miR-98-5p underexpression
    CDYL2 overexpression
    MYC amplification
    RAD21 amplification
    MYC amplification + HER-2 amplification
    MYC mutation
    MTAP deletion
    MTAP mutation
    MALAT1 overexpression
    ER-CCDC170 fusion
    ER negative + PIK3CA H1047R
    MSLN overexpression
    QPRT overexpression
    KMT5C deletion
    QPRT expression
    SOCS2 expression
    TM4SF19 expression
    miR-155 overexpression
    AFAP1-AS1 overexpression
    NCAPG overexpression
    PPP2R2B underexpression
    YES1 amplification
    HER-2 overexpression + PTEN deletion
    STK33 underexpression
    miR‐223 overexpression
    SPP1 elevation
    SPP1 mutation
    CCND1 amplification
    miR-1246 overexpression
    CEACAM6 positive + HER-2 positive
    EGFR mutation + ANKRD1 overexpression
    RET fusion + TP53 mutation
    NRG1 overexpression + ERBB3 expression
    CUL7 overexpression
    BRAF V600E
    ARPP19 overexpression
    CD44 expression
    ZNF649-AS1 overexpression
    STAT6 underexpression
    MET exon 14 mutation + EGFR exon 20 insertion
    HOTAIR overexpression
    SORL1 deletion
    PIK3CA mutation + PTEN underexpression
    BIRC5 overexpression
    BRCA1 mutation
    HGF amplification
    PTPN2 amplification
    CLU-NRG1 fusion
    CD36 overexpression
    STAT6 deletion + HER-2 overexpression
    ERBB4 H809G + ER positive
    BCL2 overexpression
    ERCC1 negative
    ERCC1 overexpression
    ANXA1 expression
    XRCC1 overexpression
    MUC4 expression
    High NLR
    High MLR
    miR-101-5p overexpression
    High PLR
    TROP2 expression
    BCL6 overexpression
    IL21R overexpression
    HER-2 positive + MYC amplification
    HER-2 positive + APC mutation
    HER-2 positive + GATA6 amplification
    HER-2 amplification + AXL expression
    HER-2 positive + CAV1 overexpression
    MPZL3 overexpression
    MLH1 mutation
    SMARCB1 mutation
    SMO mutation
    ATM mutation
    TCEAL9 overexpression
    KMT2D mutation
    SERPINH1 overexpression
    LDH elevation
    NDUFA4L2 overexpression
    EGFR G719X + TP53 mutation